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Protein Overview: SpdS-PB

General Information:
Name(s) found: SpdS-PB / FBpp0081557 [FlyBase]
Description(s) found:
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  • gi|23170822|gb|AAF54418.2| spermidine synthase, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|21355941|ref|NP_649921.1| spermidine synthase, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|16076872|gb|AAL13346.1| GH08387p [Drosophila melanogaster] [NCBI NR]
  • The gene Spermidine Synthase is referred to in FlyBase by the symbol Dmel\SpdS (CG8327, FBgn0037723). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5457361..5459395. It has the cytological map location 85E1-85E2. Based on sequence similarity, it is predicted to have molecular function</span>: spermidine synthase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: spermidine biosynthetic process. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG8327-PB translation from_gene[CG8327 CG8327 FBgn0037723] seq_release:3 mol_weight=24167 cds_boundaries:(3R:5,458,191..5,458,841[+]) aa_length:217 transcript_info:[CG8327-RB seq_release:3] gene_info:[gene symbol:CG8327 FBgn0037723 gene_boundaries:(3R [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VHA2) CG8327 protein (GH08387p) [DrosMelano7227.FASTAC.txt]
  • CG8327-PB, isoform B [Drosophila melanogaster]gi|16076872|gb|AAL13346.1| GH08387p [Drosophila melanogaster]gi|21355941|ref|NP_649921.1| CG8327-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:5458175..5458828; ID=FBpp0081557; name=SpdS-PB; parent=FBgn0037723,FBtr0082079; dbxref=FlyBase:FBpp0081557,FlyBase_Annotation_IDs:CG8327-PB,GB_protein:AAF54418.2,REFSEQ:NP_649921,GB_protein:AAF54418; MD5=10fa84956928ba46b817028a760692 [fly-100309-contam.fasta]
  • Spermidine Synthase CG8327-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH08387p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG8327-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:5458175..5458828; ID=FBpp0081557; name=SpdS-PB; parent=FBgn0037723,FBtr0082079; dbxref=FlyBase:FBpp0081557,FlyBase_Annotation_IDs:CG8327-PB,GB_protein:AAF54418.2,REFSEQ:NP_649921,GB_protein:AAF54418; MD5=10fa84956928ba46b817028a76069292; length=217; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:5458175..5458828; ID=FBpp0081557; name=SpdS-PB; parent=FBgn0037723,FBtr0082079; dbxref=FlyBase:FBpp0081557,FlyBase_Annotation_IDs:CG8327-PB,GB_protein:AAF54418.2,REFSEQ:NP_649921,GB_protein:AAF54418; MD5=10fa84956928ba46b817028a76069292; length=217; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • GH08387p OS=Drosophila melanogaster GN=SpdS PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:5458175..5458828; ID=FBpp0081557; name=SpdS-PB; parent=FBgn0037723,FBtr0082079; dbxref=FlyBase:FBpp0081557,FlyBase_Annotation_IDs:CG8327-PB,GB_protein:AAF54418.2,REFSEQ:NP_649921,GB_protein:AAF54418,FlyMine:FBpp0081557,modMine:FBpp0081557; MD5=10fa84956928ba46b817028a76069292; length=217; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:9632453..9633106; ID=FBpp0081557; name=SpdS-PB; parent=FBgn0037723,FBtr0082079; dbxref=FlyBase:FBpp0081557,FlyBase_Annotation_IDs:CG8327-PB,GB_protein:AAF54418.2,REFSEQ:NP_649921,GB_protein:AAF54418,FlyMine:FBpp0081557,modMine:FBpp0081557; MD5=10fa84956928ba46b817028a76069292; length=217; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:9632453..9633106; ID=FBpp0081557; name=SpdS-PB; parent=FBgn0037723,FBtr0082079; dbxref=FlyBase:FBpp0081557,FlyBase_Annotation_IDs:CG8327-PB,GB_protein:AAF54418.2,REFSEQ:NP_649921,GB_protein:AAF54418,FlyMine:FBpp0081557,modMine:FBpp0081557; MD5=10fa84956928ba46b817028a76069292; length=217; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VHA1, GH08387p OS=Drosophila melanogaster GN=SpdS PE=1 SV=2 [DROME.fasta.20160308]
  • FBpp0081557 type=protein; loc=3R:9632453..9633106; ID=FBpp0081557; name=SpdS-PB; parent=FBgn0037723,FBtr0082079; dbxref=FlyBase:FBpp0081557,FlyBase_Annotation_IDs:CG8327-PB,GB_protein:AAF54418.2,REFSEQ:NP_649921,GB_protein:AAF54418,FlyMine:FBpp0081557,modMine:FBpp0081557; MD5=10fa84956928ba46b817028a76069292; length=217; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:9632453..9633106; ID=FBpp0081557; name=SpdS-PB; parent=FBgn0037723,FBtr0082079; dbxref=FlyBase:FBpp0081557,FlyBase_Annotation_IDs:CG8327-PB,GB_protein:AAF54418.2,REFSEQ:NP_649921,GB_protein:AAF54418,UniProt/TrEMBL:Q9VHA2,FlyMine:FBpp0081557,modMine:FBpp0081557; MD5=10fa84956928ba46b817028a76069292; length=217; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 217 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: spermidine biosynthetic process [ISS]
    Molecular Function: spermidine synthase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISFLPLCAH PNPKKVLIVG GGDGGVAREV VKHPLVEEVH QVEIDDRVVE LSKQYLPAMA  60
   61 CGFANEKLKL TIGDGFDYMK KHKNEFDVII TDSSDPIGPA VSLFQESYYE LMKHALKDDG 120
  121 IVCSQGGSFW LDLDYIKKTM SGCKEHFAKV AYAVTSVPSY PCGHIGFVMG SLNKNQDFAT 180
  181 PKLGKSEIDS IDLRYYSSEV HSAAFALPRW VQKHFYE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..217] PSI-BLAST 48.30103 No description for 2o05A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • spermidine synthase activity
    		•  2.31131562815571 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • transferase activity
    		•  1.07321114919891 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.644010137949015 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.635463629299812 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.181420092548185 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle