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Protein Overview: AP-47-PA

General Information:
Name(s) found: AP-47-PA / FBpp0081592 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene AP-47 is referred to in FlyBase by the symbol Dmel\AP-47 (CG9388, FBgn0024833). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5383437..5385245. It has the cytological map location 85D24. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. It is reported to be involved in the biological process</span>: vesicle coating; neurotransmitter secretion; synaptic vesicle coating. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 426 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [TAS]
    clathrin adaptor complex [IEA]
    coated vesicle [TAS]
    Biological Process: vesicle coating [TAS]
    vesicle-mediated transport [IEA]
    synaptic vesicle coating [TAS]
    intracellular protein transport [IEA]
    neurotransmitter secretion [NAS]
    Molecular Function: protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSAIFVLD VKGKVLISRN YRGDNIDMAV IDKFMPLLME REEEGLITPI LQTAETTFAY  60
   61 IKTNNLYIVS TTPRNKNVNI ALVFVFLHKI AQVFVEYFKE LEEESIRDNF VIIYELLDEL 120
  121 LDFGYPQTTD SKILQEYITQ EGHKLELQPR IPVAVTNAVS WRSEGIKYRK NEVFLDVIES 180
  181 VNLLANANGN VLRSEIVGAI KMRVYLSGMP ELRLGLNDKV LFESTGRGKS KSVELEDVKF 240
  241 HQCVRLSRFE NDRTISFIPP DGEFELMSYR LNTHVKPLIW IESVIERHAH SRVEYMIKAK 300
  301 SQFKRRSTAN NVEIVIPVPA DADSPKFKTT IGSCKYAPEQ NAIIWTIKSF PGGKEYLMRA 360
  361 HFGLPSVESE DNTEGKPPIQ VRFEIPYFTT SGIQVRYLKI IEKSGYQALP WVRYITQNGD 420
  421 YQLRTN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..426] PSI-BLAST 129.0 AP1 clathrin adaptor core


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle