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Protein Overview: RacGAP84C-PA

General Information:
Name(s) found: RacGAP84C-PA / FBpp0081099 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • The gene RacGAP84C is referred to in FlyBase by the symbol Dmel\RacGAP84C (CG2595, FBgn0045843). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3110655..3113354. It has the cytological map location 84D3. There is experimental evidence that it has the molecular function</span>: GTPase activator activity. It is reported to be involved in the biological process</span>: imaginal disc-derived limb morphogenesis. 5 alleles are reported. The phenotypes of these alleles are annotated with: abdomen; dorsal closure embryo; embryonic/first instar larval cuticle; wing; wing vein; embryonic leading edge cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 384 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: intracellular signaling pathway [IEA]
    imaginal disc-derived limb morphogenesis [NAS]
    Molecular Function: GTPase activator activity [IDA][NAS]
    Ras GTPase activator activity [ISS]
    diacylglycerol binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISGSGSRTP SNRLYLSPVR PTMQNKRRLL REYRSYDDLS EHYRMFGSQS LDSLQDRVDM  60
   61 NPSGCDGLST DGLDFCSQSH SGLLREHNFK IKSYYYNVGN CVHCRKRIRF AMASLRCRAC 120
  121 PLRCHIGCCR QLTVNCIPQP QIGTKRGCLS DYAPRVAPMV PALIVHCVTE IEARGLQQEG 180
  181 LYRVSSTREK CKRLRRKLLR GKSTPHLGNK DTHTLCCCVK DFLRQLVHPL IPIYHRRDFE 240
  241 EATRHEDRLA VEMAVYLAVL ELHQAHRDTL AYLMLHWQKI AESPAVRMTV NNLAVIFAPT 300
  301 LFGDLDLTLE NVVTWQRVLK VLLLMPAGFW SQFLEVHPLP TSLGSTYDFE DRYNHRHWDS 360
  361 SSNLGWSSVK TYFRSMVNLS STHL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] PSI-BLAST 3.69897 NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE
    2 View Details [145..384] PSI-BLAST 25.30103 No description for 2ovjA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.30378408278683 bayes_pls_golite062009
  • protein binding
    		•  0.595458677481796 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle