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Protein Overview: Alh-PD

General Information:
Name(s) found: Alh-PD / FBpp0081130 [FlyBase]
Description(s) found:
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  • gi|8101613|gb|AAF72595.1|AF217960_1 Alhambra [Drosophila melanogaster] [NCBI NR]
  • gi|24644741|ref|NP_731132.1| alhambra, isoform D [Drosophila melanogaster] [NCBI NR]
  • gi|23170585|gb|AAN13343.1| alhambra, isoform D [Drosophila melanogaster] [NCBI NR]
  • The gene Alhambra is referred to in FlyBase by the symbol Dmel\Alh (CG1070, FBgn0261238). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2920318..2949907. It has the cytological map location 84B6-84C3. There is experimental evidence that it has the molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: instar larval development; haltere development; molting cycle, chitin-based cuticle. 72 alleles are reported. The phenotypes of these alleles are annotated with: larva; RP2 neuron; larval nervous system; wing. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
  • >CG1070-PA translation from_gene[CG1070 Alhambra FBgn0037471] seq_release:3 mol_weight=132884 cds_boundaries:(3R:2,924,037..2,947,370[-]) aa_length:1323 transcript_info:[CG1070-RA seq_release:3] gene_info:[gene symbol:Alhambra FBgn0037471 gene_boundari [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG1070-PD translation from_gene[CG1070 Alhambra FBgn0037471] seq_release:3 mol_weight=132884 cds_boundaries:(3R:2,924,037..2,947,370[-]) aa_length:1323 transcript_info:[CG1070-RD seq_release:3] gene_info:[gene symbol:Alhambra FBgn0037471 gene_boundari [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VI63) CG1070 protein (Alhambra) [DrosMelano7227.FASTAC.txt]
  • (AAN13343) CG1070-PD [DrosMelano7227.FASTAC.txt]
  • CG1070-PD, isoform D [Drosophila melanogaster]gi|8101613|gb|AAF72595.1| Alhambra [Drosophila melanogaster]gi|24644741|ref|NP_731132.1| CG1070-PD [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(2924033..2924205,2924277..2924454,2924548..2925244,2926859..2927219,2927321..2927819,2944680..2944770,2945184..2946604,2946664..2946860,2946997..2947351); ID=FBpp0081130; name=Alh-PD; parent=FBgn0037471,FBtr0081613; dbxref= [fly-100309-contam.fasta]
  • Alhambra CG1070-PD, isoform D [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Alhambra [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG1070-PD, isoform D [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(2924033..2924205,2924277..2924454,2924548..2925244,2926859..2927219,2927321..2927819,2944680..2944770,2945184..2946604,2946664..2946860,2946997..2947351); ID=FBpp0081130; name=Alh-PD; parent=FBgn0037471,FBtr0081613; dbxref=FlyBase:FBpp0081130,FlyBase_Annotation_IDs:CG1070-PD,GB_protein:AAN13343.1,REFSEQ:NP_731132,GB_protein:AAN13343; MD5=4b7810603bdc7ff9ae2af256e199695b; length=1323; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(2924033..2924205,2924277..2924454,2924548..2925244,2926859..2927219,2927321..2927819,2944680..2944770,2945184..2946604,2946664..2946860,2946997..2947351); ID=FBpp0081130; name=Alh-PD; parent=FBgn0261238,FBtr0081613; dbxref=FlyBase:FBpp0081130,FlyBase_Annotation_IDs:CG1070-PD,GB_protein:AAN13343.1,REFSEQ:NP_731132,GB_protein:AAN13343; MD5=4b7810603bdc7ff9ae2af256e199695b; length=1323; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Alhambra OS=Drosophila melanogaster GN=Alh PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(2924033..2924205,2924277..2924454,2924548..2925244,2926859..2927219,2927321..2927819,2944680..2944770,2945184..2946604,2946664..2946860,2946997..2947351); ID=FBpp0081130; name=Alh-PD; parent=FBgn0261238,FBtr0081613; dbxref=FlyBase:FBpp0081130,FlyBase_Annotation_IDs:CG1070-PD,GB_protein:AAN13343.1,REFSEQ:NP_731132,GB_protein:AAN13343,FlyMine:FBpp0081130,modMine:FBpp0081130; MD5=4b7810603bdc7ff9ae2af256e199695b; length=1323; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(7121275..7121629,7120942..7121138,7119462..7120882,7118958..7119048,7101599..7102097,7101137..7101497,7098826..7099522,7098555..7098732,7098311..7098483)); ID=FBpp0081130; name=Alh-PD; parent=FBgn0261238,FBtr0081613; dbxref=FlyBase:FBpp0081130,FlyBase_Annotation_IDs:CG1070-PD,GB_protein:AAN13343.1,REFSEQ:NP_731132,GB_protein:AAN13343,FlyMine:FBpp0081130,modMine:FBpp0081130; MD5=4b7810603bdc7ff9ae2af256e199695b; length=1323; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(7121275..7121629,7120942..7121138,7119462..7120882,7118958..7119048,7101599..7102097,7101137..7101497,7098826..7099522,7098555..7098732,7098311..7098483)); ID=FBpp0081130; name=Alh-PD; parent=FBgn0261238,FBtr0081613; dbxref=FlyBase:FBpp0081130,FlyBase_Annotation_IDs:CG1070-PD,GB_protein:AAN13343.1,REFSEQ:NP_731132,GB_protein:AAN13343,FlyMine:FBpp0081130,modMine:FBpp0081130; MD5=4b7810603bdc7ff9ae2af256e199695b; length=1323; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A0A0B4KGP1, Alhambra OS=Drosophila melanogaster GN=Alh PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0081130 type=protein; loc=3R:complement(join(7121275..7121629,7120942..7121138,7119462..7120882,7118958..7119048,7101599..7102097,7101137..7101497,7098826..7099522,7098555..7098732,7098311..7098483)); ID=FBpp0081130; name=Alh-PD; parent=FBgn0261238,FBtr0081613; dbxref=FlyBase:FBpp0081130,FlyBase_Annotation_IDs:CG1070-PD,GB_protein:AAN13343.1,REFSEQ:NP_731132,GB_protein:AAN13343,FlyMine:FBpp0081130,modMine:FBpp0081130; MD5=4b7810603bdc7ff9ae2af256e199695b; length=1323; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(7121275..7121629,7120942..7121138,7119462..7120882,7118958..7119048,7101599..7102097,7101137..7101497,7098826..7099522,7098555..7098732,7098311..7098483)); ID=FBpp0081130; name=Alh-PD; parent=FBgn0261238,FBtr0081613; dbxref=FlyBase:FBpp0081130,FlyBase_Annotation_IDs:CG1070-PD,GB_protein:AAN13343.1,REFSEQ:NP_731132,GB_protein:AAN13343,UniProt/TrEMBL:Q7KSZ0,FlyMine:FBpp0081130,modMine:FBpp0081130; MD5=4b7810603bdc7ff9ae2af256e199695b; length=1323; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1323 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS]
    Biological Process: molting cycle, chitin-based cuticle [IMP]
    haltere development [IGI]
    regulation of transcription, DNA-dependent [ISS]
    instar larval development [IMP]
    Molecular Function: DNA binding [ISS]
    transcription factor activity [IMP][ISS]
    zinc ion binding [IEA]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEMVGGCCV CSDERGWPEN PLVYCDGQNC TVAVHQACYG IVTVPTGPWY CRKCESQERT  60
   61 SRVRCELCPS RDGALKKTDN SGWAHVVCAL YIPEVRFGNV TTMEPIILSL IPQERYSKTC 120
  121 YICQEIGKPN RANVGACMQC NKSNCKQQFH VTCAQSLGLL CEEAGNYLDN VKYCGYCQHH 180
  181 YSKLKKGGNV KTIPPYKPIQ HDTSSDSCSS PEKEIDSTMN SATTSATIIK ITSSSGSAGG 240
  241 SSNVLNASSS AGISAGSSSG SGVSSSAKQR KSNASSKSSS SSSSSSSSST GGAPNPSSSS 300
  301 VHSGSASNMT GGGSVLPGSS NIGNISNSLN NNLPGGSSST SSAGNVPGGS GGIISASSGG 360
  361 ATQSTSSQSS TAPGTTKSSA SSSSSSSNSY KEKHSKSLSK STSSKDKDGK DSSTNSANNN 420
  421 FTNSSASSTS SNSSSTREKS SSKLSKNKDS NQVPSATSSL STTSSINTQP SSSTSTATAG 480
  481 SGGTGTHVSS SAASGLNSAP STTNEHSNHA HTLSTNGTGA GSAAGKLQSV SNLSNSSSGF 540
  541 GSDLRSVSTS SSSTVNDSTG GFGSNSNSER ENLSGAGSSA SNMPGTIAPG TGGVSSSAAT 600
  601 NLSTNKGGSS SSTANSLTST STSSGSSSNS SSKKRKADSA KSTSSISTSG SALEDNNSLI 660
  661 SRYDIKDVQV ALTPLTDFEK EIEKSSKRQR TELSPPTHQT SATAEVNAPL ASSTSASIAV 720
  721 TASATAASAP PATGTTTLGS SISGNAGSTS SGNSSGVSAT GGAQSAVGSG GYPKTESSKS 780
  781 SGTASAGSGS GSSSNTSSTK HGSNIKDISS SSNQQASTAS SSSAPSLYVS VPLSTANVPG 840
  841 INLPTSSTSS STTSESHSAS SRSSGAQSQH QQQLSNALVG PPMGGSAGAF HGGTTSAGSS 900
  901 SVIQQQSGKS SPALGTLVSG NSGGSIISAS GFPLPSGNLT ATTTESGNLK ISYEKQTTRV 960
  961 QQLQEQEAPP ARRSRTLDLS TASASSSSPS AVPATTSPLV VLSNQLPLNS VAASSSTGGL1020
 1021 KFTYESQTQM DVPMMPVSAI KDSPPSSPGS EIGSAMHSAT TAPGSLTGAS TAATAQPGNV1080
 1081 RKRGRKAKDA TIAAAAAAAA AAAALSNSQQ DLKDVRILQN GASNTPGNPA GSTPTPPATP1140
 1141 ASSNAVSSAS SIITHTAAHM LGNQINPNSS VAQKLSEQLH MEVQDHSIYT PDSMNSQYAG1200
 1201 VPFPGKQRNS TAVPSNATPA QNPLQSMFSG GGMNGNMPIP QSLEQLLERQ WEQGSQFLME1260
 1261 QAQHFDIASL LNCLHQLQSE NLRLEEHVTS LIARRDHLLA VNARLQIPLS TIASNTKAEA1320
 1321 HGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..60] PSI-BLAST 5.39794 No description for 2e6rA was found.
    2 View Details [61..274] FFAS03 0.995 No description for 2dfyX was found.
    3 View Details [275..513] deduced N/A No confident structure predictions are available.
    4 View Details [514..724] deduced N/A No confident structure predictions are available.
    5 View Details [725..899] MSA 1.143994 View MSA. No confident structure predictions are available.
    6 View Details [900..1067] MSA 2.13699 View MSA. No confident structure predictions are available.
    7 View Details [1068..1165] deduced N/A No confident structure predictions are available.
    8 View Details [1166..1323] MSA 1.106988 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle