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Protein Overview: Sym-PA

General Information:
Name(s) found: Sym-PA / FBpp0078372 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Symplekin is referred to in FlyBase by the symbol Dmel\Sym (CG2097, FBgn0037371). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1563900..1568168. It has the cytological map location 83C1-83C2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: histone mRNA 3'-end processing. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1165 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    tight junction [ISS]
    mRNA cleavage stimulating factor complex [ISS]
    Biological Process: histone mRNA 3'-end processing [IMP]
    mRNA cleavage [ISS]
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSIIGRSQF VSETANLFTD EKTATARAKV VDWCNELVIA SPSTKCELLA KVQETVLGSC  60
   61 AELAEEFLES VLSLAHDSNM EVRKQVVAFV EQVCKVKVEL LPHVINVVSM LLRDNSAQVI 120
  121 KRVIQACGSI YKNGLQYLCS LMEPGDSAEQ AWNILSLIKA QILDMIDNEN DGIRTNAIKF 180
  181 LEGVVVLQSF ADEDSLKRDG DFSLADVPDH CTLFRREKLQ EEGNNILDIL LQFHGTTHIS 240
  241 SVNLIACTSS LCTIAKMRPI FMGAVVEAFK QLNANLPPTL TDSQVSSVRK SLKMQLQTLL 300
  301 KNRGAFEFAS TIRGMLVDLG SSTNEIQKLI PKMDKQEMAR RQKRILENAA QSLAKRARLA 360
  361 CEQQDQQQRE MELDTEELER QKQKSTRVNE KFLAEHFRNP ETVVTLVLEF LPSLPTEVPQ 420
  421 KFLQEYTPIR EMSIQQQVTN ISRFFGEQLS EKRLGPGAAT FSREPPMRVK KVQAIESTLT 480
  481 AMEVDEDAVQ KLSEEEFQRK EEATKKLRET MERAKGEQTV IEKMKERAKT LKLQEITKPL 540
  541 PRNLKEKFLT DAVRRILNSE RQCIKGGVSS KRRKLVTVIA ATFPDNVRYG IMEFILEDIK 600
  601 QRIDLAFSWL FEEYSLLQGF TRHTYVKTEN RPDHAYNELL NKLIFGIGER CDHKDKIILI 660
  661 RRVYLEAPIL PEVSIGHLVQ LSLDDEFSQH GLELIKDLAV LRPPRKNRFV RVLLNFSVHE 720
  721 RLDLRDLAQA HLVSLYHVHK ILPARIDEFA LEWLKFIEQE SPPAAVFSQD FGRPTEEPDW 780
  781 REDTTKVCFG LAFTLLPYKP EVYLQQICQV FVSTSAELKR TILRSLDIPI KKMGVESPTL 840
  841 LQLIEDCPKG METLVIRIIY ILTERVPSPH EELVRRVRDL YQNKVKDVRV MIPVLSGLTR 900
  901 SELISVLPKL IKLNPAVVKE VFNRLLGIGA EFAHQTMAMT PTDILVALHT IDTSVCDIKA 960
  961 IVKATSLCLA ERDLYTQEVL MAVLQQLVEV TPLPTLMMRT TIQSLTLYPR LANFVMNLLQ1020
 1021 RLIIKQVWRQ KVIWEGFLKT VQRLKPQSMP ILLHLPPAQL VDALQQCPDL RPALSEYAES1080
 1081 MQDEPMNGSG ITQQVLDIIS GKSVDVFVTD ESGGYISAEH IKKEAPDPSE ISVISTVPVL1140
 1141 TSLVPLPVPP PIGSDLNQPL PPGED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] MSA 2.038976 View MSA. No confident structure predictions are available.
    2 View Details [145..359] deduced N/A No confident structure predictions are available.
    3 View Details [360..565] MSA 11.204997 View MSA. No confident structure predictions are available.
    4 View Details [566..632] deduced N/A No confident structure predictions are available.
    5 View Details [633..778] MSA 1.044991 View MSA. No confident structure predictions are available.
    6 View Details [779..951] deduced N/A No confident structure predictions are available.
    7 View Details [952..1091] MSA 3.030978 View MSA. No confident structure predictions are available.
    8 View Details [1092..1165] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle