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Protein Overview: CRMP-PA

General Information:
Name(s) found: CRMP-PA / FBpp0088628 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Collapsin Response Mediator Protein is referred to in FlyBase by the symbol Dmel\CRMP (CG1411, FBgn0023023). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1396830..1404913. It has the cytological map location 83B2. Based on sequence similarity, it is predicted to have molecular function</span>: dihydropyrimidinase activity. There is experimental evidence that it is involved in the biological process</span>: 'de novo' pyrimidine base biosynthetic process. 14 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 589 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: 'de novo' pyrimidine base biosynthetic process [IGI]
    Molecular Function: dihydropyrimidinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSPKPVKK VPIHLQSAQN RVYIKNGEIV NHDKSFKADV YIEDGIIKFV GPSSEITIPG  60
   61 GVRTIDASGL MIIPGGIDPH THMQLPFGGA VAVDDFYHGT KAAVAGGTTM IIDFVLPNKH 120
  121 ESMIEAYDKW RSWADPKVCC DYGLHVGITW WSKSVSEEIG ILCKELGVNS FKTFMAYKGL 180
  181 YQLNDSDLLD VFERIRHLNG VAMVHAENGD IIAKNTQRLL AEGINGPEGH ELSRPEEVEA 240
  241 EAVHRACVLA HQMKTPLFVS GLTSKSSAEL VGRARRSGYC VFGETLASSL GRSMSAVPKG 300
  301 DRIYAITSPP IRESAETPRQ LMKSLAYDDL QLTGSDNCTF NKEHKALGKG DFTKIPNGVN 360
  361 GVEDRMSLVW EKGVHAGLLD PCRFVAVTST NAAKIFNIYP QKGRIAVGSD ADIVIWNPNA 420
  421 TRTISKDTHH HACDFNIFEG MTVHGVCEFV LVRGRICAER GNVRVAEGFG RFIPTPVRPP 480
  481 FVYDIIEGKV QSQPEEQHEE KQNGSMAKRF AELDIQIPVQ EPISAMLAGN LAMPAEGSLC 540
  541 STPSVRGRVD GKRDLQESSF SISEELDRSG VRACIKVKNP PGGKSSGFW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..589] PSI-BLAST 103.0 X-ray structure of NYSGRC target T-45


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle