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Protein Overview: ash1-PA

General Information:
Name(s) found: ash1-PA / FBpp0074738 [FlyBase]
Description(s) found:
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  • gi|17737643|ref|NP_524160.1| absent, small, or homeotic discs 1 [Drosophila melanogaster] [NCBI NR]
  • gi|10727819|gb|AAF49140.2| absent, small, or homeotic discs 1 [Drosophila melanogaster] [NCBI NR]
  • The gene absent, small, or homeotic discs 1 is referred to in FlyBase by the symbol Dmel\ash1 (CG8887, FBgn0005386). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19583873..19591848. It has the cytological map location 76B8-76B9. There is experimental evidence that it has the molecular function</span>: histone-lysine N-methyltransferase activity; single-stranded RNA binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: histone methylation; oviposition; embryonic development via the syncytial blastoderm; chromatin-mediated maintenance of transcription; oogenesis; regulation of transcription. 43 alleles are reported. The phenotypes of these alleles are annotated with: abdominal segment 6; haltere; abdominal segment 2; embryonic heart; dorsal metathoracic disc; wing; imaginal disc. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG8887-PA translation from_gene[CG8887 ash1 FBgn0005386] seq_release:3 mol_weight=245722 cds_boundaries:(3L:19,541,262..19,548,177[-]) aa_length:2217 transcript_info:[CG8887-RA seq_release:3] gene_info:[gene symbol:ash1 FBgn0005386 gene_boundaries:(3L [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VW15) Ash1 protein [DrosMelano7227.FASTAC.txt]
  • (AE003516) ash1 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8887-PA [Drosophila melanogaster]gi|17737643|ref|NP_524160.1| CG8887-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:complement(19584402..19584581,19584652..19584858,19584918..19586387,19586451..19591193,19591267..19591320); ID=FBpp0074738; name=ash1-PA; parent=FBgn0005386,FBtr0074970; dbxref=GB_protein:AAF49140.2,FlyBase:FBpp0074738,FlyBase_Annotat [fly-100309-contam.fasta]
  • absent, small, or homeotic discs 1 CG8887-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG8887-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • absent, small, or homeotic discs 1 [Drosophila melanogaster] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • type=protein; loc=3L:complement(19584402..19584581,19584652..19584858,19584918..19586387,19586451..19591193,19591267..19591320); ID=FBpp0074738; name=ash1-PA; parent=FBgn0005386,FBtr0074970; dbxref=GB_protein:AAF49140.2,FlyBase:FBpp0074738,FlyBase_Annotation_IDs:CG8887-PA,REFSEQ:NP_524160,GB_protein:AAF49140; MD5=5e73b1c37da2e87ef50be4600724a6de; length=2217; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(19584402..19584581,19584652..19584858,19584918..19586387,19586451..19591193,19591267..19591320); ID=FBpp0074738; name=ash1-PA; parent=FBgn0005386,FBtr0074970; dbxref=GB_protein:AAF49140.2,FlyBase:FBpp0074738,FlyBase_Annotation_IDs:CG8887-PA,REFSEQ:NP_524160,GB_protein:AAF49140; MD5=5e73b1c37da2e87ef50be4600724a6de; length=2217; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 2217 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRQQQRFWK RNAHKNPAET DSITDQSSQS KSIKSATQFS VQRSDTDGLR MRISAIRPTL  60
   61 GVVATKKPPK SRKMSTQDTE SGCSEAKNRA VSKKVKVKRK KLASSSGISK SDKVSKSKKS 120
  121 QISAFSSDSE DDLPLKVHQQ RAPRVLLSAI IQAAQSASKP TLDIGISSSD NELPNLVQAA 180
  181 IKRVESDTED TTVEGSFRKA AKDKNLPQYQ STLLQDFMEK TQMLGQTVNA KLAEEKVAKA 240
  241 KEETLVQTAV PRKRRGRPKK VVPTVPAPGN SGPAINESAD SGVISTTSTT QSTTPSPKMQ 300
  301 NENAVPTGSL PIASSSKPKI DMAYLDKRMY ATERVLYPPP RSKRRQNNKK TACSSSNKEE 360
  361 LQLDPLWREI DVNKKFRLRS MSVGAASGTG ASTTICSKVL AAKSGYVSDY GSVRHQRSSH 420
  421 NHNSGYKSDA SCKSRYSTKS CMSRRSRAKS CGYRSDCKES GKSGLRMRRK RRASMLLKSS 480
  481 ADDTVEDQDI LQLAGLSLGQ SSEESNEYIS KPSLKSLPTT SASKKYGEIN RYVTTGQYFG 540
  541 RGGSLSATNP DNFISKMMNQ RKETPAPSKS SCKIKSRRSS AASMCSSYVS GVSRMRRRHR 600
  601 RKSFSHNKSL NIDSKLLTEI EIITSTFNSR CRIQDDRLTG SSGKEKLLAD ANKLQATLAA 660
  661 PSPAQQLTLN GGGPASTLSK PLKRGLKKRK LSEPLVDFAM LSASASGTPN GSGSSNGNTK 720
  721 RRHKKSQSND SSSPDDHKLP LKKRHYLLTP GERPPAEVAF ANGKLNAEAW AAAAAAAKST 780
  781 ASTKSQAQFN ARSVKSALTP KKRHLLEQPT SVSGAGSSAS NSPLRIVVDN NSISGGKLLD 840
  841 ISPSSLCSLK QQRRGGAAKQ KVSAAKDLVQ LQSPAGSYPP PGVFEPSVEL EIQIPLSKLN 900
  901 ESVITKAEVE SPLLSALDIK EDTKKEVGQR VVETLLHKTG GNLLLKRKRK KINRTGFPTV 960
  961 RRKKRKVSVE QQTTAVIDEH EPEFDPDDEP LQSLRETRSS NNVNVQAAPN PPLDCERVPQ1020
 1021 AGEARETFVA RTNQKAPRLS VVALERLQRP QTPARGRPRG RKPKNREQAE AAPQPPPKSE1080
 1081 PEIRPAKKRG RQPKQPVLEE PPPTPPPQQK KNKMEPNIRL PDGIDPNTNF SCKIRLKRRK1140
 1141 NLEAGTQPKK EKPVQPVTVE EIPPEIPVSQ EEIDAEAEAK RLDSIPTEHD PLPASESHNP1200
 1201 GPQDYASCSE SSEDKASTTS LRKLSKVKKT YLVAGLFSNH YKQSLMPPPA KVNKKPGLEE1260
 1261 QVGPASLLPP PPYCEKYLRR TEMDFELPYD IWWAYTNSKL PTRNVVPSWN YRKIRTNVYA1320
 1321 ESVRPNLAGF DHPTCNCKNQ GEKSCLDNCL NRMVYTECSP SNCPAGEKCR NQKIQRHAVA1380
 1381 PGVERFMTAD KGWGVRTKLP IAKGTYILEY VGEVVTEKEF KQRMASIYLN DTHHYCLHLD1440
 1441 GGLVIDGQRM GSDCRFVNHS CEPNCEMQKW SVNGLSRMVL FAKRAIEEGE ELTYDYNFSL1500
 1501 FNPSEGQPCR CNTPQCRGVI GGKSQRVKPL PAVEAKPSGE GLSGRNGRQR KQKAKKHAQR1560
 1561 QAGKDISSAV AVAKLQPLSE KEKKLVRQFN TFLVRNFEKI RRCKAKRASD AAATASSPAL1620
 1621 GTTNGDIPGR RPSTPSSPSL AAQISALCSP RNIKTRGLTQ AVHDPELEKM AKMAVVLRDI1680
 1681 CSAMETLKMS DLLTTVSSKK KKPIKTTLSG KLGSTAATSK VEFRSIQAQV EQGHYKTPQE1740
 1741 FDDHMQQLFV EAKQQHGDDE GKEKALQSLK DSYEQQKIAS YVQLVEILGD SESLQSFKPK1800
 1801 EVLSSEEEPG KIAVKKSPGA KERDSPIVPL KVTPPPLLPI EASPDEDVIR CICGLYKDEG1860
 1861 LMIQCSKCMV WQHTECTKAD IDADNYQCER CEPREVDREI PLEEFTEEGH RYYLSLMRGD1920
 1921 LQVRQGDAVY VLRDIPIKDE SGKVLPTKKH TYETIGAIDY QECDIFRVEH LWKNELGKRF1980
 1981 IFGHHFLRPH ETFHEPSRRF YPNEVVRVSL YEVVPIELVI GRCWVLDRTT FCKGRPMECN2040
 2041 DEDHCYICEL RVDKTARFFS KAKANHPACT KSYAFRKFPE KIKISKSYAP HDVDPSLLKT2100
 2101 RKQKTELDVG AGPTTMHKVS GRQEQHQAKM VGRKPRGISA PADATAVHVV TPVAPNKQML2160
 2161 KKRKSRLENV LITMKLKCLD AQTAQEQPID LSYLLSGRGA RQRKTQQSSS SSTANST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle