Protein Overview: CG7580-PA, CG758...

General Information:
Name(s) found:	FBpp0305844 [FlyBase] CG7580-PC / FBpp0291672 [FlyBase] CG7580-PB / FBpp0291671 [FlyBase] CG7580-PA / FBpp0074984 [FlyBase]
Description(s) found: Found 37 descriptions. SHOW ALL	type=protein; loc=3L:join(17468520..17468694,17468751..17468845); ID=FBpp0305844; name=CG7580-PD; parent=FBgn0036728,FBtr0333691; dbxref=REFSEQ:NP_001261987,GB_protein:AGB94680,FlyBase:FBpp0305844,FlyBase_Annotation_IDs:CG7580-PD; MD5=4fd8404cdf0b63d354276d88ce4670ba; length=89; release=r5.56; species=Dmel; [FlyBase] This gene is referred to in FlyBase by the symbol Dmel\CG7580 (CG7580, FBgn0036728). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17467861..17469224. It has the cytological map location 74C3. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquinol-cytochrome-c reductase activity; ubiquinone binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, ubiquinol to cytochrome c. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] This gene is referred to in FlyBase by the symbol Dmel\CG7580 (CG7580, FBgn0036728). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17467861..17469224. It has the cytological map location 74C3. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquinol-cytochrome-c reductase activity; ubiquinone binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, ubiquinol to cytochrome c. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] This gene is referred to in FlyBase by the symbol Dmel\CG7580 (CG7580, FBgn0036728). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17467861..17469224. It has the cytological map location 74C3. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquinol-cytochrome-c reductase activity; ubiquinone binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, ubiquinol to cytochrome c. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	89 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA] mitochondrial respiratory chain complex III [ISS]
Biological Process:	mitochondrial electron transport, ubiquinol to cytochrome c [ISS]
Molecular Function:	ubiquinol-cytochrome-c reductase activity [ISS] ubiquinone binding [ISS]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MRLSSILNGQ HFGNLAKVHG IVTYKLSPFE QRAFAGAISK GLPNMVRRFR SNVFIVTPPF 60 61 IVGYLIYDLT ERKHTALLRK NPADYANDE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

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No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..89]	PSI-BLAST	31.0	Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
ubiquinol-cytochrome-c reductase activity	11.4657297014599	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	11.4657297014599	bayes_pls_golite062009
ubiquinone binding	8.14330726546719	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	8.07004376323578	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	5.53710572481351	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	5.38577566963514	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	4.79259194111116	bayes_pls_golite062009
oxidoreductase activity	4.78909275746755	bayes_pls_golite062009
cation transmembrane transporter activity	4.5536689474984	bayes_pls_golite062009
ion transmembrane transporter activity	4.36122531415799	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.96296151827022	bayes_pls_golite062009
substrate-specific transporter activity	3.77517262558965	bayes_pls_golite062009
quinone binding	2.82234066289866	bayes_pls_golite062009
binding	1.3775057351058	bayes_pls_golite062009
cofactor binding	0.937113949001792	bayes_pls_golite062009
catalytic activity	0.442357802307605	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.54

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle