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Protein Overview: CG6485-PA

General Information:
Name(s) found: CG6485-PA / FBpp0075010 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6485 (CG6485, FBgn0036706). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17313069..17313911. It has the cytological map location 74A4. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 238 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex I [ISS]
    Biological Process: mitochondrial electron transport, NADH to ubiquinone [ISS]
    Molecular Function: NADH dehydrogenase activity [ISS]
    NAD or NADH binding [IEA]
    NADH dehydrogenase (ubiquinone) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLLQPIRR IHLAPVLRLG APVNATEIRK ALKFEFSKDN QRRVKALLAW YPQAEWKGAL  60
   61 LPLLDIAQRQ QGWLSISAVQ AVAETIKIDP MEAFEAAQFY TMFFMKPRGK YVVSVCTSTP 120
  121 CKLRGGDEIF EACKKTLNLE HGQTTPDMQF TLKEDYCMGA CVNAPVLAVN DDMYEDLDEK 180
  181 SLANILADLR NDKLPPAGPR NGRFASEPKG GLTTLKIQPP PPGFMMQKLP DPKTKKCQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..238] PSI-BLAST 49.0 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  9.90105969982332 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  8.92078442660684 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  8.81403581008074 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  8.78237088091479 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  8.15019987387908 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.56566449113494 bayes_pls_golite062009
  • electron carrier activity
    		•  1.9747415675561 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.429973830241021 bayes_pls_golite062009
  • protein binding
    		•  0.195947179962724 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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