Protein Overview: comm-PA, FBpp0305237

General Information:
Name(s) found:	FBpp0305237 [FlyBase] comm-PA / FBpp0075332 [FlyBase]
Description(s) found: Found 31 descriptions. SHOW ALL	type=protein; loc=3L:complement(15715767..15716371,15720797..15721304); ID=FBpp0305237; name=comm-PB; parent=FBgn0010105,FBtr0333023; dbxref=REFSEQ:NP_001261891,GB_protein:AGB94584,FlyBase:FBpp0305237,FlyBase_Annotation_IDs:CG17943-PB; MD5=6384075902f961ba211522381623c581; length=370; release=r5.56; species=Dmel; [FlyBase] The gene commissureless is referred to in FlyBase by the symbol Dmel\comm (CG17943, FBgn0010105). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:15715428..15721654. It has the cytological map location 71F2. There is experimental evidence that it has the molecular function</span>: WW domain binding; protein binding. There is experimental evidence that it is involved in the biological process</span>: synapse assembly; receptor internalization; positive regulation of receptor internalization; axon guidance; axon midline choice point recognition; neuron recognition; dendrite guidance. 70 alleles are reported. The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: embryonic nervous system; multi-cell-component structure; nervous system; embryonic neuron; commissure; organ system; peripheral nervous system; embryonic/larval tracheal system; antennal segment; adult segment. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	370 amino acids
Gene Ontology:
Cellular Component:	endocytic vesicle [IDA] vesicle [IDA] Golgi apparatus [IDA] plasma membrane [IDA]
Biological Process:	synapse assembly [IMP][TAS] positive regulation of receptor internalization [IMP] nervous system development [TAS] neuron recognition [IMP] axon guidance [IMP][NAS][TAS] axon midline choice point recognition [IMP][TAS] dendrite guidance [IMP] endocytosis [TAS] receptor internalization [IDA] dendrite morphogenesis [TAS]
Molecular Function:	protein binding [IPI] WW domain binding [IDA][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISTTDYPTV ETTTTAEELY AEYISAPASS MSPAAIAEHL QQNQITFEIP SAHDLRHIDA  60
   61 LNSFNALLQR IGNAAVSYDP APPSGWSPDG SISTEQLSKS VVLDLADLRD RSEESGESSW 120
  121 WSQIFGDADM HVIINYLWIG VVSSLVILSL VFILFSCYFY RKFRTWKKCN KDIRAQIHAA 180
  181 SDSYSSHLVG CDASRLLLHQ QMQHPHHRSS EAGFYQIESP PCYTIATGLP SYDEALHHQP 240
  241 RHFAYGMKFV YPSLAAVHHH HHCISNWEKQ EPLNKLQKCK LSAAAAVEED KADSSSSTSA 300
  301 SASPSSSESS NLATATPAIC INMPSGRQDE EVDNSDSDSA IAVAVAVAQS LQPAAPADDD 360
  361 CASLVVVVAA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: comm-PA, FBpp0305237

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: