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Protein Overview: NHP2-PA, FBpp0305289

General Information:
Name(s) found: FBpp0305289 [FlyBase]
NHP2-PA / FBpp0075448 [FlyBase]
Description(s) found:
Found 32 descriptions.
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  • type=protein; loc=3L:complement(14794648..14794879,14794940..14795190); ID=FBpp0305289; name=NHP2-PB; parent=FBgn0029148,FBtr0333076; dbxref=REFSEQ:NP_001261849,GB_protein:AGB94542,FlyBase:FBpp0305289,FlyBase_Annotation_IDs:CG5258-PB; MD5=abda22110bd2ce4ff1b62397e2edb16d; length=160; release=r5.56; species=Dmel; [FlyBase]
  • The gene NHP2 is referred to in FlyBase by the symbol Dmel\NHP2 (CG5258, FBgn0029148). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14794490..14795289. It has the cytological map location 70F6. Based on sequence similarity, it is predicted to have molecular function</span>: snoRNA binding; rRNA pseudouridylation guide activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: rRNA pseudouridine synthesis; rRNA processing. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 160 amino acids

    Gene Ontology:
    Cellular Component: nucleolus [NAS]
    small nucleolar ribonucleoprotein complex [ISS]
    Biological Process: rRNA pseudouridine synthesis [ISS]
    rRNA processing [ISS]
    Molecular Function: rRNA pseudouridylation guide activity [ISS]
    snoRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKVKVERSE DADESVVASG DVTIKEEESY DDKLIFVNAI AKPMAGKKLA KKCYKLVKKA  60
   61 MKHKTFLRNG LKDVQTRLRK GETGICIFAG DVTPVDIMCH LPAVCEEKGI PYTYTPSRAD 120
  121 LGAAMGVKRG TVALLVRQNE EYKDLYDEVK EELSALNIPV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] PSI-BLAST 26.522879 No description for 1zwzA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • snoRNA binding
    		•  4.95788328272916 bayes_pls_golite062009
  • RNA binding
    		•  4.7078532107994 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  3.68798692352408 bayes_pls_golite062009
  • structural molecule activity
    		•  3.12718364266877 bayes_pls_golite062009
    		• 2.493460131667 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.39301463005357 bayes_pls_golite062009
  • binding
    		•  2.14339370639382 bayes_pls_golite062009
  • mRNA binding
    		•  1.63088955572344 bayes_pls_golite062009
  • protein binding
    		•  0.281497939080747 bayes_pls_golite062009
  • catalytic activity
    		•  0.264002643439785 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle