Protein Overview: dlp-PA

General Information:
Name(s) found:	dlp-PA / FBpp0075431 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24664234\|ref\|NP_524071.2\| dally-like, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23093466\|gb\|AAF49722.2\| dally-like, isoform A [Drosophila melanogaster] [NCBI NR] gi\|15292345\|gb\|AAK93441.1\| LD47466p [Drosophila melanogaster] [NCBI NR] The gene dally-like is referred to in FlyBase by the symbol Dmel\dlp (CG32146, FBgn0041604). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14625720..14664716. It has the cytological map location 70E5-70E7. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; detection of light stimulus involved in visual perception; axon guidance; compound eye development; imaginal disc-derived wing margin morphogenesis; wing disc dorsal/ventral pattern formation; positive regulation of smoothened signaling pathway; Wnt receptor signaling pathway; regulation of imaginal disc growth; segment polarity determination. 39 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; external compound sense organ; organ system; cuticle; multi-cell-component structure; dorsal thoracic disc; compound cell cluster organ. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG32146-PA translation from_gene[CG32146 dlp FBgn0041604] seq_release:3 mol_weight=85324 cds_boundaries:(3L:14,581,953..14,619,495[+]) aa_length:765 transcript_info:[CG32146-RA seq_release:3] gene_info:[gene symbol:dlp synonyms:[CG5031 CG17703] FBgn00 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VUG1) CG32146 protein (LD47466p) [DrosMelano7227.FASTAC.txt] CG32146-PA, isoform A [Drosophila melanogaster]gi\|15292345\|gb\|AAK93441.1\| LD47466p [Drosophila melanogaster]gi\|24664234\|ref\|NP_524071.2\| CG32146-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(14626173..14626482,14657396..14657560,14657936..14658170,14660359..14660515,14660575..14660841,14662396..14662943,14663004..14663173,14663273..14663718); ID=FBpp0075431; name=dlp-PA; parent=FBgn0041604,FBtr0075679; dbxref=FlyBase [fly-100309-contam.fasta] CG32146-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] dally-like CG32146-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] LD47466p [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(14626173..14626482,14657396..14657560,14657936..14658170,14660359..14660515,14660575..14660841,14662396..14662943,14663004..14663173,14663273..14663718); ID=FBpp0075431; name=dlp-PA; parent=FBgn0041604,FBtr0075679; dbxref=FlyBase:FBpp0075431,FlyBase_Annotation_IDs:CG32146-PA,GB_protein:AAF49722.2,REFSEQ:NP_524071,GB_protein:AAF49722; MD5=a039d3324eb74df458bc4c4dc6671645; length=765; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(14626173..14626482,14657396..14657560,14657936..14658170,14660359..14660515,14660575..14660841,14662396..14662943,14663004..14663173,14663273..14663718); ID=FBpp0075431; name=dlp-PA; parent=FBgn0041604,FBtr0075679; dbxref=FlyBase:FBpp0075431,FlyBase_Annotation_IDs:CG32146-PA,GB_protein:AAF49722.2,REFSEQ:NP_524071,GB_protein:AAF49722; MD5=a039d3324eb74df458bc4c4dc6671645; length=765; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Dally-like, isoform A OS=Drosophila melanogaster GN=dlp PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(14626173..14626482,14657396..14657560,14657936..14658170,14660359..14660515,14660575..14660841,14662396..14662943,14663004..14663173,14663273..14663718); ID=FBpp0075431; name=dlp-PA; parent=FBgn0041604,FBtr0075679; dbxref=FlyBase:FBpp0075431,FlyBase_Annotation_IDs:CG32146-PA,GB_protein:AAF49722.2,REFSEQ:NP_524071,GB_protein:AAF49722,FlyMine:FBpp0075431,modMine:FBpp0075431; MD5=a039d3324eb74df458bc4c4dc6671645; length=765; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] Dally-like, isoform A OS=Drosophila melanogaster GN=dlp PE=1 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3L:join(14633073..14633382,14664296..14664460,14664836..14665070,14667259..14667415,14667475..14667741,14669296..14669843,14669904..14670073,14670173..14670618); ID=FBpp0075431; name=dlp-PA; parent=FBgn0041604,FBtr0075679; dbxref=FlyBase:FBpp0075431,FlyBase_Annotation_IDs:CG32146-PA,GB_protein:AAF49722.2,REFSEQ:NP_524071,GB_protein:AAF49722,FlyMine:FBpp0075431,modMine:FBpp0075431; MD5=a039d3324eb74df458bc4c4dc6671645; length=765; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(14633073..14633382,14664296..14664460,14664836..14665070,14667259..14667415,14667475..14667741,14669296..14669843,14669904..14670073,14670173..14670618); ID=FBpp0075431; name=dlp-PA; parent=FBgn0041604,FBtr0075679; dbxref=FlyBase:FBpp0075431,FlyBase_Annotation_IDs:CG32146-PA,GB_protein:AAF49722.2,REFSEQ:NP_524071,GB_protein:AAF49722,FlyMine:FBpp0075431,modMine:FBpp0075431; MD5=a039d3324eb74df458bc4c4dc6671645; length=765; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0075431 type=protein; loc=3L:join(14633073..14633382,14664296..14664460,14664836..14665070,14667259..14667415,14667475..14667741,14669296..14669843,14669904..14670073,14670173..14670618); ID=FBpp0075431; name=dlp-PA; parent=FBgn0041604,FBtr0075679; dbxref=FlyBase:FBpp0075431,FlyBase_Annotation_IDs:CG32146-PA,GB_protein:AAF49722.2,REFSEQ:NP_524071,GB_protein:AAF49722,FlyMine:FBpp0075431,modMine:FBpp0075431; MD5=a039d3324eb74df458bc4c4dc6671645; length=765; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(14633073..14633382,14664296..14664460,14664836..14665070,14667259..14667415,14667475..14667741,14669296..14669843,14669904..14670073,14670173..14670618); ID=FBpp0075431; name=dlp-PA; parent=FBgn0041604,FBtr0075679; dbxref=FlyBase:FBpp0075431,FlyBase_Annotation_IDs:CG32146-PA,GB_protein:AAF49722.2,REFSEQ:NP_524071,GB_protein:AAF49722,UniProt/TrEMBL:Q9VUG1,FlyMine:FBpp0075431,modMine:FBpp0075431; MD5=a039d3324eb74df458bc4c4dc6671645; length=765; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	765 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] extracellular region [ISS] proteinaceous extracellular matrix [IEA]
Biological Process:	regulation of imaginal disc growth [IMP] detection of light stimulus involved in visual perception [IMP] positive regulation of smoothened signaling pathway [IMP] Wnt receptor signaling pathway [IGI][IMP][TAS] smoothened signaling pathway [IMP][TAS] segment polarity determination [IMP] imaginal disc-derived wing margin morphogenesis [IMP] wing disc dorsal/ventral pattern formation [IEP][IGI] axon guidance [IMP] decapentaplegic receptor signaling pathway [NAS] compound eye development [IMP]
Molecular Function:	protein binding [NAS] heparan sulfate proteoglycan binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHQQQQQQH LHCRRKATAT TTARLVIFSS PLLLLLLTTH LPPTLQADNG PAPQVAALAA  60
   61 PNPAGGVAGS SIIDQFSPNC SAVTHIFQAR GIDAIEIPQK PSNERVLRYC ESPSVGTCCT 120
  121 YNMETRMAMQ SRQQLEGHTK DQISRMSGIL GSKATKFKDI FTALLKESRT QFNSMFIRTY 180
  181 GVIYERNSYV FSDLFKELET YFANGRVDLL EVMDKFFNTL YQKMFTVLNT QYTFDENYMR 240
  241 CVSEHMKELK PFGDVPDKLS VQIKRSFVAT RTYGQALTTA SEVAKKVLNV RLNADCTGAL 300
  301 TKMQHCGACK GYTEKPCTNY CVNVIKGCLH YQHEFDSEWE NFAMAMDKVA ERLLGSFNIV 360
  361 MVVEPLNIKI SEAIMNFQDS GQDITNRVFQ GCGRPKLKKM KRSISPKLQG VQILNARSPV 420
  421 EADTLDIDET LDEAIVLRER RAAEPGSQET SAQQSQEQGV GKSGNGGGGG GGNNRRQQQR 480
  481 RKQQQQRRKQ QNNRDDNDDD DNESGGGREP ILDRIVRDIR QRVKDYKKFW SNLPHSVCSN 540
  541 EDIASSSDVD GMCWNGHTID RYMHSITTEH GSNPEFTGNP ASTKQTAQMA SQLSHLKNAI 600
  601 VHLRNAYNGQ DVEWSEQEEL PYAGSGAGSG SGSEDDEDDD EGSGLGPFEP SHKPDVERPS 660
  661 VDADNDDDED AGGRGHMPTH TSRPTSGVDD KNPLIHTTHF DQDHNDLDED HRQLDEDEDT 720
  721 DAGHDGANDN RSSDAPEKMT LRRALVVYLL PLYMAWFGGV CADLL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: dlp-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: