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Protein Overview: Rgl-PA

General Information:
Name(s) found: Rgl-PA / FBpp0075535 [FlyBase]
Description(s) found:
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  • gi|6652993|gb|AAF22575.1|AF140746_1 Ral guanine nucleotide exchange factor 2 [Drosophila melanogaster] [NCBI NR]
  • gi|33589514|gb|AAQ22524.1| LD16082p [Drosophila melanogaster] [NCBI NR]
  • gi|17864274|ref|NP_524697.1| Ral guanine nucleotide exchange factor 2, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|10727938|gb|AAF49790.2| Ral guanine nucleotide exchange factor 2, isoform A [Drosophila melanogaster] [NCBI NR]
  • The gene Ral guanine nucleotide exchange factor is referred to in FlyBase by the symbol Dmel\Rgl (CG8865, FBgn0026376). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:13899991..13918348. It has the cytological map location 70C5. Based on sequence similarity, it is predicted to have molecular function</span>: Ral guanyl-nucleotide exchange factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of small GTPase mediated signal transduction. 24 alleles are reported. The phenotypes of these alleles are annotated with: eye; macrochaeta; wing; ommatidium; wing vein. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • >CG8865-PA translation from_gene[CG8865 Rgl FBgn0026376] seq_release:3 mol_weight=108078 cds_boundaries:(3L:13,856,707..13,868,073[-]) aa_length:954 transcript_info:[CG8865-RA seq_release:3] gene_info:[gene symbol:Rgl FBgn0026376 gene_boundaries:(3L:13 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9U4U5) RAL guanine nucleotide exchange factor 2 (RGL protein) (LD16082p) [DrosMelano7227.FASTAC.txt]
  • (AE003536) Rgl gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8865-PA, isoform A [Drosophila melanogaster]gi|33589514|gb|AAQ22524.1| LD16082p [Drosophila melanogaster]gi|6652993|gb|AAF22575.1| Ral guanine nucleotide exchange factor 2 [Drosophila melanogaster]gi|17864274|ref|NP_524697.1| CG8865-PA [Drosophila me [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:complement(13900924..13902069,13902131..13902283,13902356..13902868,13902932..13903315,13903584..13903685,13907062..13907625,13912291..13912293); ID=FBpp0075535; name=Rgl-PA; parent=FBgn0026376,FBtr0075793; dbxref=FlyBase:FBpp0075535, [fly-100309-contam.fasta]
  • LD16082p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Ral guanine nucleotide exchange factor 2 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG8865-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Ral guanine nucleotide exchange factor 2 CG8865-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:complement(13900924..13902069,13902131..13902283,13902356..13902868,13902932..13903315,13903584..13903685,13907062..13907625,13912291..13912293); ID=FBpp0075535; name=Rgl-PA; parent=FBgn0026376,FBtr0075793; dbxref=FlyBase:FBpp0075535,FlyBase_Annotation_IDs:CG8865-PA,GB_protein:AAF49790.2,REFSEQ:NP_524697,GB_protein:AAF49790; MD5=6747e9ec3d0da53fdf285c1a22d3ef59; length=954; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(13900924..13902069,13902131..13902283,13902356..13902868,13902932..13903315,13903584..13903685,13907062..13907625,13912291..13912293); ID=FBpp0075535; name=Rgl-PA; parent=FBgn0026376,FBtr0075793; dbxref=FlyBase:FBpp0075535,FlyBase_Annotation_IDs:CG8865-PA,GB_protein:AAF49790.2,REFSEQ:NP_524697,GB_protein:AAF49790; MD5=6747e9ec3d0da53fdf285c1a22d3ef59; length=954; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • LD16082p OS=Drosophila melanogaster GN=Rgl PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:complement(13900924..13902069,13902131..13902283,13902356..13902868,13902932..13903315,13903584..13903685,13907062..13907625,13912291..13912293); ID=FBpp0075535; name=Rgl-PA; parent=FBgn0026376,FBtr0075793; dbxref=FlyBase:FBpp0075535,FlyBase_Annotation_IDs:CG8865-PA,GB_protein:AAF49790.2,REFSEQ:NP_524697,GB_protein:AAF49790,FlyMine:FBpp0075535,modMine:FBpp0075535; MD5=6747e9ec3d0da53fdf285c1a22d3ef59; length=954; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:complement(join(13919191..13919193,13913962..13914525,13910484..13910585,13909832..13910215,13909256..13909768,13909031..13909183,13907824..13908969)); ID=FBpp0075535; name=Rgl-PA; parent=FBgn0026376,FBtr0075793; dbxref=FlyBase:FBpp0075535,FlyBase_Annotation_IDs:CG8865-PA,GB_protein:AAF49790.2,REFSEQ:NP_524697,GB_protein:AAF49790,FlyMine:FBpp0075535,modMine:FBpp0075535; MD5=6747e9ec3d0da53fdf285c1a22d3ef59; length=954; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:complement(join(13919191..13919193,13913962..13914525,13910484..13910585,13909832..13910215,13909256..13909768,13909031..13909183,13907824..13908969)); ID=FBpp0075535; name=Rgl-PA; parent=FBgn0026376,FBtr0075793; dbxref=FlyBase:FBpp0075535,FlyBase_Annotation_IDs:CG8865-PA,GB_protein:AAF49790.2,REFSEQ:NP_524697,GB_protein:AAF49790,FlyMine:FBpp0075535,modMine:FBpp0075535; MD5=6747e9ec3d0da53fdf285c1a22d3ef59; length=954; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of M9PCE9, LD16082p OS=Drosophila melanogaster GN=Rgl PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0075535 type=protein; loc=3L:complement(join(13919191..13919193,13913962..13914525,13910484..13910585,13909832..13910215,13909256..13909768,13909031..13909183,13907824..13908969)); ID=FBpp0075535; name=Rgl-PA; parent=FBgn0026376,FBtr0075793; dbxref=FlyBase:FBpp0075535,FlyBase_Annotation_IDs:CG8865-PA,GB_protein:AAF49790.2,REFSEQ:NP_524697,GB_protein:AAF49790,FlyMine:FBpp0075535,modMine:FBpp0075535; MD5=6747e9ec3d0da53fdf285c1a22d3ef59; length=954; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:complement(join(13919191..13919193,13913962..13914525,13910484..13910585,13909832..13910215,13909256..13909768,13909031..13909183,13907824..13908969)); ID=FBpp0075535; name=Rgl-PA; parent=FBgn0026376,FBtr0075793; dbxref=FlyBase:FBpp0075535,FlyBase_Annotation_IDs:CG8865-PA,GB_protein:AAF49790.2,REFSEQ:NP_524697,GB_protein:AAF49790,UniProt/TrEMBL:Q9U4U5,FlyMine:FBpp0075535,modMine:FBpp0075535; MD5=6747e9ec3d0da53fdf285c1a22d3ef59; length=954; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 954 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: regulation of small GTPase mediated signal transduction [IEA]
    Molecular Function: RAL GDP-dissociation stimulator activity [NAS]
    Ral guanyl-nucleotide exchange factor activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFTSRANCK CPHSQKHQQK PALIKSHTCA YQLQDLTGYN RALMPPLDNT DFSNAWRQVN  60
   61 NNTTSQSCAY HQQRQQQQQQ QDAKDSKRHY HHHTCPRQRK KSMTPVEPTH LCQKHQEAKQ 120
  121 RRSRSASAKP RRNSSYHSYD DLDVSSAVLN AERKVVASLK YLCACTGATL RNLSKKTKDL 180
  181 HAKNYTYTKP TWRLWGEEHE KNAIFTVYLK KVRYHRPTPT ASNDSDDEIS HLEWETVRVR 240
  241 FVKAATLARL VEALATDDGE LESTFINVFL STYRTFSTPK QVLSLLTQRY DALHEKHLEE 300
  301 LEQAQQNGQV MDPAYDPHAS IHEQHKKTLV SALHVWLDGF PEDWHEDNLQ QILAFATKRL 360
  361 KRSDLHIKVL NRLERLIKQS LYGNGGGSGG SENNGHSWLS AARSQQMQQF MIPTHYGSSY 420
  421 DLTDQFNGMY LSPMGHGPIY RGPTHFLQAF RFPHVPVRHF AEQLTRMDTE LFKRLIPHQC 480
  481 LGHTWARRDS GGSETVVATI NQFNAVLFRV VSSILIDRLK PQERALNISR WIDIAQELRM 540
  541 LKNFSSLKAI ISALNSNSIY RLSKIWEVLP KERMEVFTEL ANICSEDNNA WTLREVLKRE 600
  601 GTAKNPDPGS DHSDRHLQKL ILNLGTQTSH GTIPYLGTFL TDLTMIHTAN PDYLTENKLI 660
  661 NFDKKRKEFE VLAQIKLLQG AANTYNLQAD ALFDHWFNSM PVFDEREAFE LSCRLEPPPP 720
  721 APRKSVVSTN TSLTNTTASS TASIMGHRKT DSIHSNSSSG AGSQFYCELN SSTSSRHNSL 780
  781 DRDVHHQHAS LMSASSSVSN LSLDSSNSGG RQSGKLTHSQ SMGNGLKSHG NGTTNGGSPH 840
  841 INAQLVQPSS GTPHSAPDFY IIRVTYETDN IELDGIVLYK SIMLGNNERT PQVIRNAMLK 900
  901 LGLEDDPDRF TLAQVLPDKE LVMPKNANVY YAVNTNYNLN FILRPRKEEG VAGS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle