Protein Overview: flr-PA

General Information:
Name(s) found:	flr-PA / FBpp0075581 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7294479\|gb\|AAF49822.1\| CG10724, isoform A [Drosophila melanogaster] [NCBI NR] gi\|21356527\|ref\|NP_648642.1\| CG10724, isoform A [Drosophila melanogaster] [NCBI NR] gi\|16769338\|gb\|AAL28888.1\| LD27045p [Drosophila melanogaster] [NCBI NR] gi\|12230779\|sp\|Q9VU68.1\|WDR1_DROME RecName: Full=Actin-interacting protein 1; Short=AIP1; AltName: Full=Protein flare [NCBI NR] Actin-interacting protein 1 OS=Drosophila melanogaster GN=flr PE=2 SV=1 [Swiss-Prot] The gene flare is referred to in FlyBase by the symbol Dmel\flr (CG10724, FBgn0260049). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:13405930..13409554. It has the cytological map location 70A8-70B1. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: actin filament depolymerization; imaginal disc-derived wing hair organization; phagocytosis, engulfment. 16 alleles are reported. The phenotypes of these alleles are annotated with: trichome; macrochaeta; microchaeta; socket; wing hair. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG10724-PA translation from_gene[CG10724 CG10724 FBgn0036357] seq_release:3 mol_weight=66550 cds_boundaries:(3L:13,370,510..13,373,669[+]) aa_length:608 transcript_info:[CG10724-RA seq_release:3] gene_info:[gene symbol:CG10724 FBgn0036357 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta] (Q9VU68) Putative actin interacting protein 1 (AIP1) [DrosMelano7227.FASTAC.txt] (AE003538) CG10724 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG10724-PA, isoform A [Drosophila melanogaster]gi\|16769338\|gb\|AAL28888.1\| LD27045p [Drosophila melanogaster]gi\|21356527\|ref\|NP_648642.1\| CG10724-PA [Drosophila melanogaster]gi\|12230779\|sp\|Q9VU68\|WDR1_DROME Putative actin interacting protein 1 (AIP1) [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(13406042..13406075,13406417..13406538,13407158..13407248,13407437..13407700,13407766..13408820,13408877..13409027,13409095..13409204); ID=FBpp0075581; name=flr-PA; parent=FBgn0260049,FBtr0075845; dbxref=FlyBase:FBpp0075581,FlyBas [fly-100309-contam.fasta] CG10724-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Putative actin-interacting protein 1 (AIP1) [nr-271106-contam.fasta] LD27045p [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(13406042..13406075,13406417..13406538,13407158..13407248,13407437..13407700,13407766..13408820,13408877..13409027,13409095..13409204); ID=FBpp0075581; name=flr-PA; parent=FBgn0260049,FBtr0075845; dbxref=FlyBase:FBpp0075581,FlyBase_Annotation_IDs:CG10724-PA,GB_protein:AAF49822.1,REFSEQ:NP_648642,GB_protein:AAF49822; MD5=2903fc0b443bce3b745b2cd4f45eeecc; length=608; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(13406042..13406075,13406417..13406538,13407158..13407248,13407437..13407700,13407766..13408820,13408877..13409027,13409095..13409204); ID=FBpp0075581; name=flr-PA; parent=FBgn0260049,FBtr0075845; dbxref=FlyBase:FBpp0075581,FlyBase_Annotation_IDs:CG10724-PA,GB_protein:AAF49822.1,REFSEQ:NP_648642,GB_protein:AAF49822; MD5=2903fc0b443bce3b745b2cd4f45eeecc; length=608; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:join(13406042..13406075,13406417..13406538,13407158..13407248,13407437..13407700,13407766..13408820,13408877..13409027,13409095..13409204); ID=FBpp0075581; name=flr-PA; parent=FBgn0260049,FBtr0075845; dbxref=FlyBase:FBpp0075581,FlyBase_Annotation_IDs:CG10724-PA,GB_protein:AAF49822.1,REFSEQ:NP_648642,GB_protein:AAF49822,FlyMine:FBpp0075581,modMine:FBpp0075581; MD5=2903fc0b443bce3b745b2cd4f45eeecc; length=608; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(13412942..13412975,13413317..13413438,13414058..13414148,13414337..13414600,13414666..13415720,13415777..13415927,13415995..13416104); ID=FBpp0075581; name=flr-PA; parent=FBgn0260049,FBtr0075845; dbxref=FlyBase:FBpp0075581,FlyBase_Annotation_IDs:CG10724-PA,GB_protein:AAF49822.1,REFSEQ:NP_648642,GB_protein:AAF49822,FlyMine:FBpp0075581,modMine:FBpp0075581; MD5=2903fc0b443bce3b745b2cd4f45eeecc; length=608; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(13412942..13412975,13413317..13413438,13414058..13414148,13414337..13414600,13414666..13415720,13415777..13415927,13415995..13416104); ID=FBpp0075581; name=flr-PA; parent=FBgn0260049,FBtr0075845; dbxref=FlyBase:FBpp0075581,FlyBase_Annotation_IDs:CG10724-PA,GB_protein:AAF49822.1,REFSEQ:NP_648642,GB_protein:AAF49822,FlyMine:FBpp0075581,modMine:FBpp0075581; MD5=2903fc0b443bce3b745b2cd4f45eeecc; length=608; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0075581 type=protein; loc=3L:join(13412942..13412975,13413317..13413438,13414058..13414148,13414337..13414600,13414666..13415720,13415777..13415927,13415995..13416104); ID=FBpp0075581; name=flr-PA; parent=FBgn0260049,FBtr0075845; dbxref=FlyBase:FBpp0075581,FlyBase_Annotation_IDs:CG10724-PA,GB_protein:AAF49822.1,REFSEQ:NP_648642,GB_protein:AAF49822,FlyMine:FBpp0075581,modMine:FBpp0075581; MD5=2903fc0b443bce3b745b2cd4f45eeecc; length=608; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(13412942..13412975,13413317..13413438,13414058..13414148,13414337..13414600,13414666..13415720,13415777..13415927,13415995..13416104); ID=FBpp0075581; name=flr-PA; parent=FBgn0260049,FBtr0075845; dbxref=FlyBase:FBpp0075581,FlyBase_Annotation_IDs:CG10724-PA,GB_protein:AAF49822.1,REFSEQ:NP_648642,GB_protein:AAF49822,UniProt/Swiss-Prot:Q9VU68,FlyMine:FBpp0075581,modMine:FBpp0075581; MD5=2903fc0b443bce3b745b2cd4f45eeecc; length=608; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	608 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	phagocytosis, engulfment [IMP] actin polymerization or depolymerization [ISS] actin filament depolymerization [IMP][ISS] imaginal disc-derived wing hair organization [IMP]
Molecular Function:	actin binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQPQPPAYE NKNIYATLPR TQRGQPIVLG ADPKGKNFLY TNGNSVIIRN IENPAIADVY  60
   61 TEHSCAVNVA KYSPSGFYIA SGDASGKIRI WDTVNKEHLL KNEFQPIAGP IKDISWSPDN 120
  121 QRIVAVGEGR ERFGHVFMSE TGTSVGEISG QSKSINSADF RPARPFRIVT GSEDNTIAVF 180
  181 EGPPFKFKMT KQDHSRFVQA VRYSPDGKFF ASAGFDGKVF LYDGTSSELV GEFGSPAHKG 240
  241 GVYALAWKPD STQLLTCSGD KTCRLWTVES RELVSEFVMG TTVDDQQVSC LWQGDNLITV 300
  301 SLSGVITYLN VADPSKPLRV VKGHNKPITV LGLSDDRSTI YTGSHDGVVT NWNSGSGTND 360
  361 RITGTGHGNQ INGIAAWGDF VYTCGIDDSL RQFSVEGNSY TDYVVKLNCQ PRGLAILRNE 420
  421 NIIALACIKE LTLVQDQKKI FSLPIKYEAS SIAVNADTSD VAVGGDDQKL HIYTLKGGVL 480
  481 EPKVELDHLG AVTDVSYSPD LKYLVACDAH RKVVLYSVEE YKPAHNKEWG FHSARVNTVA 540
  541 WSPNSLLVAS GSLDTTIIIW SVANPAKHTI IKNAHPQSQI TRLVWLDNNT VISTGQDCNT 600
  601 KVWHVENI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: flr-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: