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Protein Overview: TfIIEalpha-PA

General Information:
Name(s) found: TfIIEalpha-PA / FBpp0075839 [FlyBase]
Description(s) found:
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  • gi|7294692|gb|AAF50029.1| transcription factor IIEalpha [Drosophila melanogaster] [NCBI NR]
  • gi|4098000|gb|AAD00187.1| TFIIE large subunit [Drosophila melanogaster] [NCBI NR]
  • gi|21428868|gb|AAM50153.1| GH11150p [Drosophila melanogaster] [NCBI NR]
  • gi|17648007|ref|NP_524026.1| transcription factor IIEalpha [Drosophila melanogaster] [NCBI NR]
  • The gene Transcription factor IIEÃ?&#142;Ã?± is referred to in FlyBase by the symbol Dmel\TfIIEÃ?&#142;Ã?± (CG10415, FBgn0015828). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11675126..11676905. It has the cytological map location 68D2. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription initiation from RNA polymerase II promoter. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG10415-PA translation from_gene[CG10415 TfIIEalpha FBgn0015828] seq_release:3 mol_weight=48286 cds_boundaries:(3L:11,639,860..11,641,214[+]) aa_length:429 transcript_info:[CG10415-RA seq_release:3] gene_info:[gene symbol:TfIIEalpha FBgn0015828 gene_b [hmr_yeast5_DM3-1_pombe.fasta]
  • (O96880) TFIIEALPHA protein (GH11150p) [DrosMelano7227.FASTAC.txt]
  • (AE003544) TfIIEalpha gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG10415-PA [Drosophila melanogaster]gi|21428868|gb|AAM50153.1| GH11150p [Drosophila melanogaster]gi|4098000|gb|AAD00187.1| TFIIE large subunit [Drosophila melanogaster]gi|17648007|ref|NP_524026.1| CG10415-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:join(11675412..11676507,11676576..11676769); ID=FBpp0075839; name=TfIIEalpha-PA; parent=FBgn0015828,FBtr0076108; dbxref=FlyBase:FBpp0075839,FlyBase_Annotation_IDs:CG10415-PA,GB_protein:AAF50029.1,REFSEQ:NP_524026,GB_protein:AAF50029; [fly-100309-contam.fasta]
  • CG10415-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Transcription factor IIEalpha CG10415-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH11150p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • TFIIE large subunit [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:join(11675412..11676507,11676576..11676769); ID=FBpp0075839; name=TfIIEalpha-PA; parent=FBgn0015828,FBtr0076108; dbxref=FlyBase:FBpp0075839,FlyBase_Annotation_IDs:CG10415-PA,GB_protein:AAF50029.1,REFSEQ:NP_524026,GB_protein:AAF50029; MD5=53ea87e54cbeb52b8a761954ede5d396; length=429; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(11675412..11676507,11676576..11676769); ID=FBpp0075839; name=TfIIEalpha-PA; parent=FBgn0015828,FBtr0076108; dbxref=FlyBase:FBpp0075839,FlyBase_Annotation_IDs:CG10415-PA,GB_protein:AAF50029.1,REFSEQ:NP_524026,GB_protein:AAF50029; MD5=53ea87e54cbeb52b8a761954ede5d396; length=429; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • GH11150p OS=Drosophila melanogaster GN=TfIIEalpha PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:join(11675412..11676507,11676576..11676769); ID=FBpp0075839; name=TfIIEalpha-PA; parent=FBgn0015828,FBtr0076108; dbxref=FlyBase:FBpp0075839,FlyBase_Annotation_IDs:CG10415-PA,GB_protein:AAF50029.1,REFSEQ:NP_524026,GB_protein:AAF50029,FlyMine:FBpp0075839,modMine:FBpp0075839; MD5=53ea87e54cbeb52b8a761954ede5d396; length=429; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • GH11150p OS=Drosophila melanogaster GN=TfIIEalpha PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3L:join(11682312..11683407,11683476..11683669); ID=FBpp0075839; name=TfIIEalpha-PA; parent=FBgn0015828,FBtr0076108; dbxref=FlyBase:FBpp0075839,FlyBase_Annotation_IDs:CG10415-PA,GB_protein:AAF50029.1,REFSEQ:NP_524026,GB_protein:AAF50029,FlyMine:FBpp0075839,modMine:FBpp0075839; MD5=53ea87e54cbeb52b8a761954ede5d396; length=429; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(11682312..11683407,11683476..11683669); ID=FBpp0075839; name=TfIIEalpha-PA; parent=FBgn0015828,FBtr0076108; dbxref=FlyBase:FBpp0075839,FlyBase_Annotation_IDs:CG10415-PA,GB_protein:AAF50029.1,REFSEQ:NP_524026,GB_protein:AAF50029,FlyMine:FBpp0075839,modMine:FBpp0075839; MD5=53ea87e54cbeb52b8a761954ede5d396; length=429; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0075839 type=protein; loc=3L:join(11682312..11683407,11683476..11683669); ID=FBpp0075839; name=TfIIEalpha-PA; parent=FBgn0015828,FBtr0076108; dbxref=FlyBase:FBpp0075839,FlyBase_Annotation_IDs:CG10415-PA,GB_protein:AAF50029.1,REFSEQ:NP_524026,GB_protein:AAF50029,FlyMine:FBpp0075839,modMine:FBpp0075839; MD5=53ea87e54cbeb52b8a761954ede5d396; length=429; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:join(11682312..11683407,11683476..11683669); ID=FBpp0075839; name=TfIIEalpha-PA; parent=FBgn0015828,FBtr0076108; dbxref=FlyBase:FBpp0075839,FlyBase_Annotation_IDs:CG10415-PA,GB_protein:AAF50029.1,REFSEQ:NP_524026,GB_protein:AAF50029,UniProt/TrEMBL:O96880,FlyMine:FBpp0075839,modMine:FBpp0075839; MD5=53ea87e54cbeb52b8a761954ede5d396; length=429; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 429 amino acids

    Gene Ontology:
    Cellular Component: transcription factor TFIIE complex [ISS]
    Biological Process: transcription initiation from RNA polymerase II promoter [ISS]
    Molecular Function: general RNA polymerase II transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTSTAAAN AAPAKTEVRY VTEVPSSLKQ LARLVVRGFY SLEDALIIDM LVRNPCMKED  60
   61 DIGELLRFEK KQLRARITTL RTDKFIQIRL KMETGPDGKA QKVNYYFINY KTFVNVVKYK 120
  121 LDLMRKRMET EERDATSRAS FKCSSCSKTF TDLEADQLFD MATLEFRCTF CGSSVEEDSA 180
  181 AMPKKDSRLM LAHFNEQLQP LYDLLREVEG IKLAPEVLEP EPVDIDTIRG LNKPNATRPD 240
  241 GMAWSGEATR NQGFAVEETR VDVTIGGDDT SDAVIERKSR PIWMTESTVI TDTDAADGAA 300
  301 DAVQTASGSG HRNRKENEDI MSVLLQHEKQ PGQKEPHMKG MRVGSSNANS SDSSDDEKDI 360
  361 ENSKIPDVDF DNYINSDSAE EDDDVPTVLV AGRPHPLDQL DDNLIAQMTP QEKENYIHVY 420
  421 QQHYSHIFE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle