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Protein Overview: FBpp0303606, APP...

General Information:
Name(s) found: FBpp0303606 [FlyBase]
APP-BP1-PA / FBpp0075938 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • type=protein; loc=3L:join(11091785..11091852,11091910..11092074,11092131..11092776,11092843..11093176,11093239..11093487,11093547..11093659); ID=FBpp0303606; name=APP-BP1-PB; parent=FBgn0261112,FBtr0331179; dbxref=FlyBase:FBpp0303606,FlyBase_Annotation_IDs:CG7828-PB,REFSEQ:NP_001261699,GB_protein:AGB94393; MD5=f349a34f7a1ee5916955e5ee2710af2c; length=524; release=r5.56; species=Dmel; [FlyBase]
  • The gene Ã?&#142;Ã?²-Amyloid precursor protein binding protein 1 is referred to in FlyBase by the symbol Dmel\APP-BP1 (CG7828, FBgn0261112). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11091512..11093678. It has the cytological map location 68A6. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin activating enzyme activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 8 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; scutellar bristle; imaginal disc; scutellum. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 524 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEA]
    Molecular Function: ubiquitin activating enzyme activity [ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPAPKSPE LSDKSKKYDR QIRLWGEHGQ TLLEAATVCL VNVTAVGCET AKGLVLPGIG  60
   61 GFTVADGSTV KEEDLGNNFF LDSSYLGKSK ALACMQLLQE LNPDVNGDYV DESADFLLAN 120
  121 RPNFFDSFDL VIASNLNEQT LLLLAERLWE LNVPLIYCRS LGMLGTIRLQ IREHCIVEAH 180
  181 PDNRQFDLRL EHPFDALREH LDGTEVTSKV PWLLVLHKYL NVWQKQQADG TQTPRNYKEK 240
  241 NQLKETIREE MKADEENYEE AIKAVNTAFG AGQVPKSLKA IFEDDACEQL NKKSNVFWIM 300
  301 AKALKHFVIH ENEGHLPLPG VLPDMTANTD SYIALQHIYR QQALQDADQV YHKCQEYLKQ 360
  361 LALPADSIDE RSVRLICKEA AGLAVIRGTR IAEEYEKSSR LLPLVEDNEL QGNLTAYNFA 420
  421 LRAYERFLSE CGNIPGECIV EQDIGRLKSI AAKMLSDLGM HATISDDVLH EICRYGGAEL 480
  481 HAVSAFIGGC AAQEVIKIIT KQYKPIDNTF IYNAITTESV TLKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle