Protein Overview: can-PA

General Information:
Name(s) found:	can-PA / FBpp0076028 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7294830\|gb\|AAF50162.1\| cannonball [Drosophila melanogaster] [NCBI NR] gi\|17864464\|ref\|NP_524827.1\| cannonball [Drosophila melanogaster] [NCBI NR] gi\|13958634\|gb\|AAK50884.1\| cannonball [Drosophila melanogaster] [NCBI NR] The gene cannonball is referred to in FlyBase by the symbol Dmel\can (CG6577, FBgn0011569). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10257007..10260211. It has the cytological map location 67D12. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: male meiosis I; spermatid development; spermatogenesis. 21 alleles are reported. The phenotypes of these alleles are annotated with: testis; spermatocyte. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG6577-PA translation from_gene[CG6577 can FBgn0011569] seq_release:3 mol_weight=108472 cds_boundaries:(3L:10,221,519..10,224,594[-]) aa_length:942 transcript_info:[CG6577-RA seq_release:3] gene_info:[gene symbol:can FBgn0011569 gene_boundaries:(3L:10 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VT91) CG6577 protein (CANNONBALL) [DrosMelano7227.FASTAC.txt] (AE003549) CG6577 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG6577-PA [Drosophila melanogaster]gi\|17864464\|ref\|NP_524827.1\| CG6577-PA [Drosophila melanogaster]gi\|13958634\|gb\|AAK50884.1\| cannonball [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(10257087..10259370,10259427..10259579,10259646..10259706,10259761..10260052,10260127..10260165); ID=FBpp0076028; name=can-PA; parent=FBgn0011569,FBtr0076299; dbxref=FlyBase:FBpp0076028,FlyBase_Annotation_IDs:CG6577-PA,GB_pr [fly-100309-contam.fasta] cannonball [Drosophila melanogaster] [nr-271106-contam.fasta] cannonball CG6577-PA [Drosophila melanogaster] [nr-271106-contam.fasta] CG6577-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(10257087..10259370,10259427..10259579,10259646..10259706,10259761..10260052,10260127..10260165); ID=FBpp0076028; name=can-PA; parent=FBgn0011569,FBtr0076299; dbxref=FlyBase:FBpp0076028,FlyBase_Annotation_IDs:CG6577-PA,GB_protein:AAF50162.1,REFSEQ:NP_524827,GB_protein:AAF50162; MD5=1aafe2afcd2516da13906b459ccb5f0c; length=942; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(10257087..10259370,10259427..10259579,10259646..10259706,10259761..10260052,10260127..10260165); ID=FBpp0076028; name=can-PA; parent=FBgn0011569,FBtr0076299; dbxref=FlyBase:FBpp0076028,FlyBase_Annotation_IDs:CG6577-PA,GB_protein:AAF50162.1,REFSEQ:NP_524827,GB_protein:AAF50162; MD5=1aafe2afcd2516da13906b459ccb5f0c; length=942; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Cannonball OS=Drosophila melanogaster GN=can PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:complement(10257087..10259370,10259427..10259579,10259646..10259706,10259761..10260052,10260127..10260165); ID=FBpp0076028; name=can-PA; parent=FBgn0011569,FBtr0076299; dbxref=FlyBase:FBpp0076028,FlyBase_Annotation_IDs:CG6577-PA,GB_protein:AAF50162.1,REFSEQ:NP_524827,GB_protein:AAF50162,FlyMine:FBpp0076028,modMine:FBpp0076028; MD5=1aafe2afcd2516da13906b459ccb5f0c; length=942; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] Cannonball OS=Drosophila melanogaster GN=can PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3L:complement(join(10267027..10267065,10266661..10266952,10266546..10266606,10266327..10266479,10263987..10266270)); ID=FBpp0076028; name=can-PA; parent=FBgn0011569,FBtr0076299; dbxref=FlyBase:FBpp0076028,FlyBase_Annotation_IDs:CG6577-PA,GB_protein:AAF50162.1,REFSEQ:NP_524827,GB_protein:AAF50162,FlyMine:FBpp0076028,modMine:FBpp0076028; MD5=1aafe2afcd2516da13906b459ccb5f0c; length=942; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(10267027..10267065,10266661..10266952,10266546..10266606,10266327..10266479,10263987..10266270)); ID=FBpp0076028; name=can-PA; parent=FBgn0011569,FBtr0076299; dbxref=FlyBase:FBpp0076028,FlyBase_Annotation_IDs:CG6577-PA,GB_protein:AAF50162.1,REFSEQ:NP_524827,GB_protein:AAF50162,FlyMine:FBpp0076028,modMine:FBpp0076028; MD5=1aafe2afcd2516da13906b459ccb5f0c; length=942; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0076028 type=protein; loc=3L:complement(join(10267027..10267065,10266661..10266952,10266546..10266606,10266327..10266479,10263987..10266270)); ID=FBpp0076028; name=can-PA; parent=FBgn0011569,FBtr0076299; dbxref=FlyBase:FBpp0076028,FlyBase_Annotation_IDs:CG6577-PA,GB_protein:AAF50162.1,REFSEQ:NP_524827,GB_protein:AAF50162,FlyMine:FBpp0076028,modMine:FBpp0076028; MD5=1aafe2afcd2516da13906b459ccb5f0c; length=942; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(10267027..10267065,10266661..10266952,10266546..10266606,10266327..10266479,10263987..10266270)); ID=FBpp0076028; name=can-PA; parent=FBgn0011569,FBtr0076299; dbxref=FlyBase:FBpp0076028,FlyBase_Annotation_IDs:CG6577-PA,GB_protein:AAF50162.1,REFSEQ:NP_524827,GB_protein:AAF50162,UniProt/TrEMBL:Q9VT91,FlyMine:FBpp0076028,modMine:FBpp0076028; MD5=1aafe2afcd2516da13906b459ccb5f0c; length=942; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	942 amino acids
Gene Ontology:
Cellular Component:	transcription factor TFIID complex [ISS] nucleolus [IDA]
Biological Process:	spermatid development [IMP][TAS] spermatogenesis [IMP] male meiosis I [IMP] regulation of transcription [IEA] meiosis [TAS] transcription initiation from RNA polymerase II promoter [ISS]
Molecular Function:	general RNA polymerase II transcription factor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLPLPILIP SSDEVYVISD SDDSDSDDIR NELMKLEDNK DKPKNKERQK SKNENSQIKM  60
   61 NKWYLKEFED LMGLEIACSD DEDDIDDRNS EIWSSSESDK ISDSDDSNSD GSPTEWINRI 120
  121 KNVNLFPFNK SAEDEKPKAC EELPSIPVFT GPMPSMPIYD EETCQFEMVP PIIQPDLIKE 180
  181 VTDAEMPIEL DKSDSELEKE KLKADEDDNF SDSNTSSSFS LSSLDDYDYG ETDLDEQHNE 240
  241 NKCTYWEEMS LRPVDKGEVS QEELMAILNE DESSPDHRSE CDIDEAIRTR DGSDFYEDSA 300
  301 QFLENMENVS LLVIKEDSVF ADYEFAVKKL IKLIQSTPSH YKYEIYILLY PLLVLTYLQM 360
  361 MASDKIQKAR MLLVRFQDHL DDSYISRIIK LREISKPAEV PNKARKLLAG LEKVKIEMSE 420
  421 GAFRQLLLCT EEWTRGQQEK LLSHFQIQPY SEDDKPQQRF AIGQPLLEPI WYGAPEPLHK 480
  481 KDFAARPFFQ KRRKKRSEPQ LSDNLHLPPV NRVYNPIPNK MDLLHMKSDE QYRMKLDRNN 540
  541 LPSTYLYTTS PSDEVVICAT FSEGNSMLAL GTVSSKVYVF SLKPSKLVQV KAAQWLKNLD 600
  601 TGMAGVDKDM IDPIKKFTRR TLYGHQGPVY GCSFNPEDRF LITCSEDFSV RLWCLLSWSC 660
  661 VVIFSGHLAP VCFVVFAPRG YYFATASDDC TARVWMQDNT KPARILQGHL AELGVCLFHP 720
  721 NRHYMATGSA DCTVRIWDIV KAVQVRIFRG HKSRITALIY SICGRYLVSG GDDNLIMIWD 780
  781 TANEILMQFF DHHKASINTM EISLDNNILV VGGQDCQLTL WDFEQVIKNY LNRAKISMKN 840
  841 QAGTQESSAN NLLVSSFFTK GEPFYMIRFT RRNLLLGFCV TPREFENDVL DVKLNQNKHK 900
  901 EEKKKELGEW LDFLDTIKLK ACYDLKDEIN LDTSQVEKEN KS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.72

Protein Overview: can-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: