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Protein Overview: Doc2-PA

General Information:
Name(s) found: Doc2-PA / FBpp0076274 [FlyBase]
Description(s) found:
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  • gi|7295001|gb|AAF50329.1| Dorsocross2, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|62472117|ref|NP_001014578.1| Dorsocross2, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|61678470|gb|AAX52749.1| Dorsocross2, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|21355555|ref|NP_648282.1| Dorsocross2, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|20136133|gb|AAM11545.1|AF444797_1 Dorsocross2 [Drosophila melanogaster] [NCBI NR]
  • gi|20136131|gb|AAM11544.1|AF444796_1 Dorsocross2 [Drosophila melanogaster] [NCBI NR]
  • gi|19527593|gb|AAL89911.1| RE40937p [Drosophila melanogaster] [NCBI NR]
  • The gene Dorsocross2 is referred to in FlyBase by the symbol Dmel\Doc2 (CG5187, FBgn0035956). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9005780..9013509. It has the cytological map location 66F1. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: cardiac cell differentiation. 10 alleles are reported. The phenotypes of these alleles are annotated with: extended germ band embryo; somatic mesoderm; wing; arista; wing vein; embryonic pericardial cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG5187-PA translation from_gene[CG5187 Doc2 FBgn0035956] seq_release:3 mol_weight=51174 cds_boundaries:(3L:8,971,579..8,977,601[-]) aa_length:469 transcript_info:[CG5187-RA seq_release:3] gene_info:[gene symbol:Doc2 FBgn0035956 gene_boundaries:(3L:8,9 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VST2) CG5187 protein (RE40937p) (Dorsocross2) [DrosMelano7227.FASTAC.txt]
  • (AE003553) CG5187 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG5187-PA [Drosophila melanogaster]gi|20136133|gb|AAM11545.1| Dorsocross2 [Drosophila melanogaster]gi|20136131|gb|AAM11544.1| Dorsocross2 [Drosophila melanogaster]gi|19527593|gb|AAL89911.1| RE40937p [Drosophila melanogaster]gi|21355555|ref|NP_648282.1 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:complement(9005966..9006721,9007592..9007729,9007808..9008075,9011029..9011185,9011901..9011991); ID=FBpp0099775; name=Doc2-PB; parent=FBgn0035956,FBtr0100367; dbxref=FlyBase_Annotation_IDs:CG5187-PB,FlyBase:FBpp0099775,GB_protein:AAX [fly-100309-contam.fasta]
  • type=protein; loc=3L:complement(9005966..9006721,9007592..9007729,9007808..9008075,9011029..9011185,9011901..9011991); ID=FBpp0076274; name=Doc2-PA; parent=FBgn0035956,FBtr0076547; dbxref=FlyBase_Annotation_IDs:CG5187-PA,FlyBase:FBpp0076274,GB_protein:AAF [fly-100309-contam.fasta]
  • Dorsocross2 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Dorsocross2 CG5187-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG5187-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE40937p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG5187-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Dorsocross2 CG5187-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:complement(9005966..9006721,9007592..9007729,9007808..9008075,9011029..9011185,9011901..9011991); ID=FBpp0099775; name=Doc2-PB; parent=FBgn0035956,FBtr0100367; dbxref=FlyBase_Annotation_IDs:CG5187-PB,FlyBase:FBpp0099775,GB_protein:AAX52749.1,REFSEQ:NP_001014578,GB_protein:AAX52749; MD5=d0994a2d9a6c72d79021f63c85657085; length=469; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(9005966..9006721,9007592..9007729,9007808..9008075,9011029..9011185,9011901..9011991); ID=FBpp0076274; name=Doc2-PA; parent=FBgn0035956,FBtr0076547; dbxref=FlyBase_Annotation_IDs:CG5187-PA,FlyBase:FBpp0076274,GB_protein:AAF50329.1,REFSEQ:NP_648282,GB_protein:AAF50329; MD5=d0994a2d9a6c72d79021f63c85657085; length=469; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(9005966..9006721,9007592..9007729,9007808..9008075,9011029..9011185,9011901..9011991); ID=FBpp0099775; name=Doc2-PB; parent=FBgn0035956,FBtr0100367; dbxref=FlyBase_Annotation_IDs:CG5187-PB,FlyBase:FBpp0099775,GB_protein:AAX52749.1,REFSEQ:NP_001014578,GB_protein:AAX52749; MD5=d0994a2d9a6c72d79021f63c85657085; length=469; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:complement(9005966..9006721,9007592..9007729,9007808..9008075,9011029..9011185,9011901..9011991); ID=FBpp0076274; name=Doc2-PA; parent=FBgn0035956,FBtr0076547; dbxref=FlyBase_Annotation_IDs:CG5187-PA,FlyBase:FBpp0076274,GB_protein:AAF50329.1,REFSEQ:NP_648282,GB_protein:AAF50329; MD5=d0994a2d9a6c72d79021f63c85657085; length=469; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Dorsocross2 OS=Drosophila melanogaster GN=Doc2 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:complement(9005966..9006721,9007592..9007729,9007808..9008075,9011029..9011185,9011901..9011991); ID=FBpp0076274; name=Doc2-PA; parent=FBgn0035956,FBtr0076547; dbxref=FlyBase_Annotation_IDs:CG5187-PA,FlyBase:FBpp0076274,GB_protein:AAF50329.1,REFSEQ:NP_648282,GB_protein:AAF50329,FlyMine:FBpp0076274,modMine:FBpp0076274; MD5=d0994a2d9a6c72d79021f63c85657085; length=469; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • Dorsocross2 OS=Drosophila melanogaster GN=Doc2 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3L:complement(join(9018801..9018891,9017929..9018085,9014708..9014975,9014492..9014629,9012866..9013621)); ID=FBpp0076274; name=Doc2-PA; parent=FBgn0035956,FBtr0076547; dbxref=FlyBase_Annotation_IDs:CG5187-PA,FlyBase:FBpp0076274,GB_protein:AAF50329.1,REFSEQ:NP_648282,GB_protein:AAF50329,FlyMine:FBpp0076274,modMine:FBpp0076274; MD5=d0994a2d9a6c72d79021f63c85657085; length=469; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:complement(join(9018801..9018891,9017929..9018085,9014708..9014975,9014492..9014629,9012866..9013621)); ID=FBpp0076274; name=Doc2-PA; parent=FBgn0035956,FBtr0076547; dbxref=FlyBase_Annotation_IDs:CG5187-PA,FlyBase:FBpp0076274,GB_protein:AAF50329.1,REFSEQ:NP_648282,GB_protein:AAF50329,FlyMine:FBpp0076274,modMine:FBpp0076274; MD5=d0994a2d9a6c72d79021f63c85657085; length=469; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0076274 type=protein; loc=3L:complement(join(9018801..9018891,9017929..9018085,9014708..9014975,9014492..9014629,9012866..9013621)); ID=FBpp0076274; name=Doc2-PA; parent=FBgn0035956,FBtr0076547; dbxref=FlyBase_Annotation_IDs:CG5187-PA,FlyBase:FBpp0076274,GB_protein:AAF50329.1,REFSEQ:NP_648282,GB_protein:AAF50329,FlyMine:FBpp0076274,modMine:FBpp0076274; MD5=d0994a2d9a6c72d79021f63c85657085; length=469; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:complement(join(9018801..9018891,9017929..9018085,9014708..9014975,9014492..9014629,9012866..9013621)); ID=FBpp0076274; name=Doc2-PA; parent=FBgn0035956,FBtr0076547; dbxref=FlyBase_Annotation_IDs:CG5187-PA,FlyBase:FBpp0076274,GB_protein:AAF50329.1,REFSEQ:NP_648282,GB_protein:AAF50329,UniProt/TrEMBL:Q9VST2,FlyMine:FBpp0076274,modMine:FBpp0076274; MD5=d0994a2d9a6c72d79021f63c85657085; length=469; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 469 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: cardiac cell differentiation [IMP]
    regulation of transcription, DNA-dependent [IEA]
    regulation of transcription [IEA][ISS]
    Molecular Function: transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITMNELVDL RMQQHIAHEI YRQQIMQRIP DPFPPMLPIP MPRHVIMPPR VTLPGVEMTL  60
   61 QNDDLWKQFH QIGTEMIITK SGRRMFPSMR LSVSGLEDES NYCVLLEMVP IGDCRYKFSG 120
  121 SQWVPAGGAE PQSPQRMYLH PDSPATGAHW QAQPILFNKV KLTNNTLDNS GHIVLASMHK 180
  181 YQPRLHVIRT ADLAQIPWAP QQAFVFAETE FVAVTAYQND RITKLKIDNN PFAKGFRETG 240
  241 QSRCKRKMSS SPTGEDQDQS PSLSHSQSQS ESDMSPTKGG GETAGGTSSI GDSDGPQIKR 300
  301 LRSNGSACSL SSSLDDQSVP GASSLALGSP PPHLHSHSHP HPLQARSASS VFMQHFQQNM 360
  361 QSLLRPSLVD LACTYFGRPH EYGGAIQASP MYPPAAMLQA GLGPHPGLNL PPGVSGADLI 420
  421 SDESGAEELE LDVGSETSTL EQSTQEQPLE QPSTRSKGFS ISAILGGGS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle