Protein Overview: Idh-PC

General Information:
Name(s) found:	Idh-PC / FBpp0076393 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7295108\|gb\|AAF50434.1\| isocitrate dehydrogenase, isoform C [Drosophila melanogaster] [NCBI NR] gi\|21356561\|ref\|NP_652044.1\| isocitrate dehydrogenase, isoform C [Drosophila melanogaster] [NCBI NR] The gene Isocitrate dehydrogenase is referred to in FlyBase by the symbol Dmel\Idh (CG7176, FBgn0001248). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8349503..8354628. It has the cytological map location 66C8. There is experimental evidence that it has the molecular function</span>: isocitrate dehydrogenase (NADP+) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: glyoxylate cycle; tricarboxylic acid cycle. 20 alleles are reported. No phenotypic data is available. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase] >CG7176-PC translation from_gene[CG7176 Idh FBgn0001248] seq_release:3 mol_weight=52590 cds_boundaries:(3L:8,315,368..8,317,367[-]) aa_length:469 transcript_info:[CG7176-RC seq_release:3] gene_info:[gene symbol:Idh FBgn0001248 gene_boundaries:(3L:8,315 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VSI6) Lethal (3) L3852 protein [DrosMelano7227.FASTAC.txt] (AE003555) CG7176 gene product [alt 3] [Drosophila melanogaster] [yeastflysequest.fasta] CG7176-PC, isoform C [Drosophila melanogaster]gi\|21356561\|ref\|NP_652044.1\| CG7176-PC [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(8349755..8351005,8351116..8351172,8351656..8351757); ID=FBpp0076393; name=Idh-PC; parent=FBgn0001248,FBtr0076670; dbxref=FlyBase:FBpp0076393,FlyBase_Annotation_IDs:CG7176-PC,GB_protein:AAF50434.1,REFSEQ:NP_652044,GB_protein [fly-100309-contam.fasta] CG7176-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta] Isocitrate dehydrogenase CG7176-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(8349755..8351005,8351116..8351172,8351656..8351757); ID=FBpp0076393; name=Idh-PC; parent=FBgn0001248,FBtr0076670; dbxref=FlyBase:FBpp0076393,FlyBase_Annotation_IDs:CG7176-PC,GB_protein:AAF50434.1,REFSEQ:NP_652044,GB_protein:AAF50434; MD5=7626da4ffd9e5c0ab3c0685550c804d0; length=469; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(8349755..8351005,8351116..8351172,8351656..8351757); ID=FBpp0076393; name=Idh-PC; parent=FBgn0001248,FBtr0076670; dbxref=FlyBase:FBpp0076393,FlyBase_Annotation_IDs:CG7176-PC,GB_protein:AAF50434.1,REFSEQ:NP_652044,GB_protein:AAF50434; MD5=7626da4ffd9e5c0ab3c0685550c804d0; length=469; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Isocitrate dehydrogenase [NADP] OS=Drosophila melanogaster GN=Idh PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:complement(8349755..8351005,8351116..8351172,8351656..8351757); ID=FBpp0076393; name=Idh-PC; parent=FBgn0001248,FBtr0076670; dbxref=FlyBase:FBpp0076393,FlyBase_Annotation_IDs:CG7176-PC,GB_protein:AAF50434.1,REFSEQ:NP_652044,GB_protein:AAF50434,FlyMine:FBpp0076393,modMine:FBpp0076393; MD5=7626da4ffd9e5c0ab3c0685550c804d0; length=469; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(join(8358556..8358657,8358016..8358072,8356655..8357905)); ID=FBpp0076393; name=Idh-PC; parent=FBgn0001248,FBtr0076670; dbxref=FlyBase:FBpp0076393,FlyBase_Annotation_IDs:CG7176-PC,GB_protein:AAF50434.1,REFSEQ:NP_652044,GB_protein:AAF50434,FlyMine:FBpp0076393,modMine:FBpp0076393; MD5=7626da4ffd9e5c0ab3c0685550c804d0; length=469; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(8358556..8358657,8358016..8358072,8356655..8357905)); ID=FBpp0076393; name=Idh-PC; parent=FBgn0001248,FBtr0076670; dbxref=FlyBase:FBpp0076393,FlyBase_Annotation_IDs:CG7176-PC,GB_protein:AAF50434.1,REFSEQ:NP_652044,GB_protein:AAF50434,FlyMine:FBpp0076393,modMine:FBpp0076393; MD5=7626da4ffd9e5c0ab3c0685550c804d0; length=469; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of B7Z0E0, Isocitrate dehydrogenase [NADP] OS=Drosophila melanogaster GN=Idh PE=1 SV=1 [DROME.fasta.20160308] FBpp0076393 type=protein; loc=3L:complement(join(8358556..8358657,8358016..8358072,8356655..8357905)); ID=FBpp0076393; name=Idh-PC; parent=FBgn0001248,FBtr0076670; dbxref=FlyBase:FBpp0076393,FlyBase_Annotation_IDs:CG7176-PC,GB_protein:AAF50434.1,REFSEQ:NP_652044,GB_protein:AAF50434,FlyMine:FBpp0076393,modMine:FBpp0076393; MD5=7626da4ffd9e5c0ab3c0685550c804d0; length=469; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(8358556..8358657,8358016..8358072,8356655..8357905)); ID=FBpp0076393; name=Idh-PC; parent=FBgn0001248,FBtr0076670; dbxref=FlyBase:FBpp0076393,FlyBase_Annotation_IDs:CG7176-PC,GB_protein:AAF50434.1,REFSEQ:NP_652044,GB_protein:AAF50434,UniProt/TrEMBL:Q7KUB1,FlyMine:FBpp0076393,modMine:FBpp0076393; MD5=7626da4ffd9e5c0ab3c0685550c804d0; length=469; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	469 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA] mitochondrion [ISS]
Biological Process:	glyoxylate cycle [ISS] isocitrate metabolic process [IEA] tricarboxylic acid cycle [ISS] oxidation reduction [IEA]
Molecular Function:	magnesium ion binding [IEA] NAD or NADH binding [IEA] isocitrate dehydrogenase (NADP+) activity [IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFALRRTAAM MTSVHRQPHL SQAVFRANFA ISAADPKTHK ISMDNERMSA VSEMAQKIKA  60
   61 GPVVDVLGDE MTRIIWDSIK SQLILPFLDI ELHTYDLGIE NRDKTEDQVT IDCAEAIKKY 120
  121 NVGIKCATIT PDEKRVEEFN LKKMWKSPNG TIRNILGGTV FREAIICKNV PRLVTGWQKP 180
  181 IVIGRHAHAD QYKAVDYVVP GPGKLTLTWK GTDGQVIDEV INDFKGPGIA LGMFNTDDSI 240
  241 VDFAHASFKY ALDRKLPLYM STKNTILKKY DGRFKDIFED LYNKQYKKEY EAAGIWYEHR 300
  301 LIDDMVAYAM KSEGGFVWAC KNYDGDVQSD SVAQGYGSLG LMTSVLLCPD GKTVEAEAAH 360
  361 GTVTRHFRFY QQGKETSTNP IASIFAWTRG LLHRAKLDNN EPLKQFADTL EQVCIDTIES 420
  421 GAMTKDLAIC IKGNINAVTR RDYQETFEFI NTLAKNLEGA LAKNAVAAK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Idh-PC

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: