Protein Overview: Idh-PF, Idh-PA

General Information:
Name(s) found:	Idh-PF / FBpp0076391 [FlyBase] Idh-PA / FBpp0076390 [FlyBase]
Description(s) found: Found 37 descriptions. SHOW ALL	The gene Isocitrate dehydrogenase is referred to in FlyBase by the symbol Dmel\Idh (CG7176, FBgn0001248). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8349503..8354628. It has the cytological map location 66C8. There is experimental evidence that it has the molecular function</span>: isocitrate dehydrogenase (NADP+) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: glyoxylate cycle; tricarboxylic acid cycle. 20 alleles are reported. No phenotypic data is available. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase] The gene Isocitrate dehydrogenase is referred to in FlyBase by the symbol Dmel\Idh (CG7176, FBgn0001248). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8349503..8354628. It has the cytological map location 66C8. There is experimental evidence that it has the molecular function</span>: isocitrate dehydrogenase (NADP+) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: glyoxylate cycle; tricarboxylic acid cycle. 20 alleles are reported. No phenotypic data is available. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	416 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA] mitochondrion [ISS]
Biological Process:	glyoxylate cycle [ISS] isocitrate metabolic process [IEA] tricarboxylic acid cycle [ISS] oxidation reduction [IEA]
Molecular Function:	magnesium ion binding [IEA] NAD or NADH binding [IEA] isocitrate dehydrogenase (NADP+) activity [IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQKIKAGPV VDVLGDEMTR IIWDSIKSQL ILPFLDIELH TYDLGIENRD KTEDQVTIDC  60
   61 AEAIKKYNVG IKCATITPDE KRVEEFNLKK MWKSPNGTIR NILGGTVFRE AIICKNVPRL 120
  121 VTGWQKPIVI GRHAHADQYK AVDYVVPGPG KLTLTWKGTD GQVIDEVIND FKGPGIALGM 180
  181 FNTDDSIVDF AHASFKYALD RKLPLYMSTK NTILKKYDGR FKDIFEDLYN KQYKKEYEAA 240
  241 GIWYEHRLID DMVAYAMKSE GGFVWACKNY DGDVQSDSVA QGYGSLGLMT SVLLCPDGKT 300
  301 VEAEAAHGTV TRHFRFYQQG KETSTNPIAS IFAWTRGLLH RAKLDNNEPL KQFADTLEQV 360
  361 CIDTIESGAM TKDLAICIKG NINAVTRRDY QETFEFINTL AKNLEGALAK NAVAAK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: Idh-PF, Idh-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: