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Protein Overview: FBpp0306707, Hn-PA

General Information:
Name(s) found: FBpp0306707 [FlyBase]
Hn-PA / FBpp0076523 [FlyBase]
Description(s) found:
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  • gi|7295194|gb|AAF50517.1| henna, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|24660393|ref|NP_523963.2| henna, isoform A [Drosophila melanogaster] [NCBI NR]
  • pir||JC4888 phenylalanine 4-monooxygenase (EC 1.14.16.1) - fruit fly (Drosophila melanogaster) [NCBI NR]
  • gi|17861948|gb|AAL39451.1| HL08079p [Drosophila melanogaster] [NCBI NR]
  • gi|1483313|emb|CAA66797.1| phenylalanine hydroxylase; tryptophan hydroxylase [Drosophila melanogaster] [NCBI NR]
  • gi|12644139|sp|P17276.3|PH4H_DROME RecName: Full=Protein henna; Includes: RecName: Full=Phenylalanine-4-hydroxylase; Short=PAH; AltName: Full=Phe-4-monooxygenase; Includes: RecName: Full=Tryptophan 5-monooxygenase; AltName: Full=Tryptophan 5-hydroxylase; [NCBI NR]
  • Protein henna OS=Drosophila melanogaster GN=Hn PE=2 SV=3 [Swiss-Prot]
  • type=protein; loc=3L:join(7753727..7753756,7754663..7755335,7755394..7755656,7755722..7755951,7756012..7756174); ID=FBpp0306707; name=Hn-PC; parent=FBgn0001208,FBtr0334645; dbxref=FlyBase:FBpp0306707,FlyBase_Annotation_IDs:CG7399-PC,REFSEQ:NP_001261542,GB_protein:AGB94237; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r5.56; species=Dmel; [FlyBase]
  • The gene Henna is referred to in FlyBase by the symbol Dmel\Hn (CG7399, FBgn0001208). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:7753577..7756268. It has the cytological map location 66A12. There is experimental evidence that it has the molecular function</span>: phenylalanine 4-monooxygenase activity. There is experimental evidence that it is involved in the biological process</span>: L-phenylalanine catabolic process; eye pigment biosynthetic process; phagocytosis, engulfment. 18 alleles are reported. The phenotypes of these alleles are annotated with: eye; pigment cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG7399-PA translation from_gene[CG7399 Hn FBgn0001208] seq_release:3 mol_weight=51661 cds_boundaries:(3L:7,720,156..7,722,600[+]) aa_length:452 transcript_info:[CG7399-RA seq_release:3] gene_info:[gene symbol:Hn FBgn0001208 gene_boundaries:(3L:7,720,0 [hmr_yeast5_DM3-1_pombe.fasta]
  • (P17276) Protein henna [Includes: Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4-monooxygenase); Tryptophan 5-monooxygenase (EC 1.14.16.4) (TRH) (Tryptophan 5-hydroxylase)] [DrosMelano7227.FASTAC.txt]
  • (AE003558) Hn gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG7399-PA [Drosophila melanogaster]gi|17861948|gb|AAL39451.1| HL08079p [Drosophila melanogaster]gi|24660393|ref|NP_523963.2| CG7399-PA [Drosophila melanogaster]gi|1483313|emb|CAA66797.1| phenylalanine hydroxylase; tryptophan hydroxylase [Drosophila mel [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:join(7753727..7753756,7754663..7755335,7755394..7755656,7755722..7755951,7756012..7756174); ID=FBpp0076523; name=Hn-PA; parent=FBgn0001208,FBtr0076811; dbxref=FlyBase_Annotation_IDs:CG7399-PA,FlyBase:FBpp0076523,GB_protein:AAF50517.1, [fly-100309-contam.fasta]
  • Protein henna [Includes: Phenylalanine-4-hydroxylase (PAH) (Phe-4-monooxygenase); Tryptophan 5-monooxygenase (TRH) (Tryptophan 5-hydroxylase)] [nr-271106-contam.fasta]
  • HL08079p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG7399-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Henna CG7399-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • phenylalanine hydroxylase; tryptophan hydroxylase [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:join(7753727..7753756,7754663..7755335,7755394..7755656,7755722..7755951,7756012..7756174); ID=FBpp0076523; name=Hn-PA; parent=FBgn0001208,FBtr0076811; dbxref=FlyBase_Annotation_IDs:CG7399-PA,FlyBase:FBpp0076523,GB_protein:AAF50517.1,REFSEQ:NP_523963,GB_protein:AAF50517; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(7753727..7753756,7754663..7755335,7755394..7755656,7755722..7755951,7756012..7756174); ID=FBpp0076523; name=Hn-PA; parent=FBgn0001208,FBtr0076811; dbxref=FlyBase_Annotation_IDs:CG7399-PA,FlyBase:FBpp0076523,GB_protein:AAF50517.1,REFSEQ:NP_523963,GB_protein:AAF50517; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Protein henna OS=Drosophila melanogaster GN=Hn PE=1 SV=3 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:join(7753727..7753756,7754663..7755335,7755394..7755656,7755722..7755951,7756012..7756174); ID=FBpp0076523; name=Hn-PA; parent=FBgn0001208,FBtr0076811; dbxref=FlyBase_Annotation_IDs:CG7399-PA,FlyBase:FBpp0076523,GB_protein:AAF50517.1,REFSEQ:NP_523963,GB_protein:AAF50517,FlyMine:FBpp0076523,modMine:FBpp0076523; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(7760627..7760656,7761563..7762235,7762294..7762556,7762622..7762851,7762912..7763074); ID=FBpp0076523; name=Hn-PA; parent=FBgn0001208,FBtr0076811; dbxref=FlyBase_Annotation_IDs:CG7399-PA,FlyBase:FBpp0076523,GB_protein:AAF50517.1,REFSEQ:NP_523963,GB_protein:AAF50517,FlyMine:FBpp0076523,modMine:FBpp0076523; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(7760627..7760656,7761563..7762235,7762294..7762556,7762622..7762851,7762912..7763074); ID=FBpp0306707; name=Hn-PC; parent=FBgn0001208,FBtr0334645; dbxref=FlyBase:FBpp0306707,FlyBase_Annotation_IDs:CG7399-PC,REFSEQ:NP_001261542,GB_protein:AGB94237; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(7760627..7760656,7761563..7762235,7762294..7762556,7762622..7762851,7762912..7763074); ID=FBpp0306707; name=Hn-PC; parent=FBgn0001208,FBtr0334645; dbxref=FlyBase:FBpp0306707,FlyBase_Annotation_IDs:CG7399-PC,REFSEQ:NP_001261542,GB_protein:AGB94237; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3L:join(7760627..7760656,7761563..7762235,7762294..7762556,7762622..7762851,7762912..7763074); ID=FBpp0076523; name=Hn-PA; parent=FBgn0001208,FBtr0076811; dbxref=FlyBase_Annotation_IDs:CG7399-PA,FlyBase:FBpp0076523,GB_protein:AAF50517.1,REFSEQ:NP_523963,GB_protein:AAF50517,FlyMine:FBpp0076523,modMine:FBpp0076523; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of P17276, Henna, isoform C OS=Drosophila melanogaster GN=Hn PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0076523 type=protein; loc=3L:join(7760627..7760656,7761563..7762235,7762294..7762556,7762622..7762851,7762912..7763074); ID=FBpp0076523; name=Hn-PA; parent=FBgn0001208,FBtr0076811; dbxref=FlyBase_Annotation_IDs:CG7399-PA,FlyBase:FBpp0076523,GB_protein:AAF50517.1,REFSEQ:NP_523963,GB_protein:AAF50517,FlyMine:FBpp0076523,modMine:FBpp0076523; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0306707 type=protein; loc=3L:join(7760627..7760656,7761563..7762235,7762294..7762556,7762622..7762851,7762912..7763074); ID=FBpp0306707; name=Hn-PC; parent=FBgn0001208,FBtr0334645; dbxref=FlyBase:FBpp0306707,FlyBase_Annotation_IDs:CG7399-PC,REFSEQ:NP_001261542,GB_protein:AGB94237; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:join(7760627..7760656,7761563..7762235,7762294..7762556,7762622..7762851,7762912..7763074); ID=FBpp0076523; name=Hn-PA; parent=FBgn0001208,FBtr0076811; dbxref=FlyBase_Annotation_IDs:CG7399-PA,FlyBase:FBpp0076523,GB_protein:AAF50517.1,REFSEQ:NP_523963,GB_protein:AAF50517,UniProt/Swiss-Prot:P17276,FlyMine:FBpp0076523,modMine:FBpp0076523; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3L:join(7760627..7760656,7761563..7762235,7762294..7762556,7762622..7762851,7762912..7763074); ID=FBpp0306707; name=Hn-PC; parent=FBgn0001208,FBtr0334645; dbxref=FlyBase:FBpp0306707,FlyBase_Annotation_IDs:CG7399-PC,REFSEQ:NP_001261542,GB_protein:AGB94237,UniProt/Swiss-Prot:P17276; MD5=1c95da0a67fe0ff270dad8a0000cd726; length=452; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 452 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    Biological Process: eye pigment biosynthetic process [IDA]
    L-phenylalanine catabolic process [IMP][NAS]
    phagocytosis, engulfment [IMP]
    oxidation reduction [IEA]
    Molecular Function: phenylalanine 4-monooxygenase activity [IDA][IMP][ISS][NAS]
    iron ion binding [IEA]
    tryptophan 5-monooxygenase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYQRQVSFDK PTRVEDSAYI VEGVDIKEAR NTCLLFSPKD SSLSSGALAN ILAIFKKHDI  60
   61 NLVHIESRSS LRVPGYEFFV EADGKSGALG KAIEDVKEQC SYFNIISRDY KDNATAVPWF 120
  121 PRRIRDLDRF ANQILSYGSE LDADHPGFTD PEYRKRRKYF ADIAYNYKHG EPLPHVDYTK 180
  181 EEIETWGIIF RNLTKLYKTH ACREYNHVFP LLVDNCGFRE DNIPQLEDVS NFLRDCTGFT 240
  241 LRPVAGLLSS RDFLAGLAFR VFHSTQYIRH PSKPMYTPEP DVCHELMGHV PLFADPAFAQ 300
  301 FSQEIGLASL GAPDDYIEKL STIFWFTVEY GVCRQEGELK AYGAGLLSSY GELEYCLTDK 360
  361 PQLKDFEPEV TGVTKYPITQ FQPLYYVADS FETAKEKTIK FANSIPRPFG VRYNAYTQSV 420
  421 EVLDSKPQIS NLMDNINSEF QILQNAVAKL RV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle