Protein Overview: ple-PB, FBpp0311654

General Information:
Name(s) found:	FBpp0311654 [FlyBase] ple-PB / FBpp0076666 [FlyBase]
Description(s) found: Found 32 descriptions. SHOW ALL	type=protein; loc=3L:complement(6708070..6708468,6708808..6708934,6709230..6710049,6710434..6710526,6710653..6710772,6711004..6711115,6712105..6712173); ID=FBpp0311654; name=ple-PC; parent=FBgn0005626,FBtr0345585; dbxref=FlyBase:FBpp0311654,FlyBase_Annotation_IDs:CG10118-PC; MD5=ea749e9e2e10405e5ae16bdf3eec704b; length=579; release=r5.56; species=Dmel; [FlyBase] The gene pale is referred to in FlyBase by the symbol Dmel\ple (CG10118, FBgn0005626). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:6706455..6712624. It has the cytological map location 65C3. Based on sequence similarity, it is predicted to have molecular function</span>: tyrosine 3-monooxygenase activity. There is experimental evidence that it is involved in the biological process</span>: dopamine biosynthetic process; adult locomotory behavior; male courtship behavior. 23 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; spiracle; cephalopharyngeal skeleton; cuticle; macrochaeta; adult abdomen; wing cell; mouth hooks. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	579 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	developmental pigmentation [TAS] dopamine biosynthetic process [IMP] aromatic amino acid family metabolic process [IEA] regulation of dopamine metabolic process [NAS] courtship behavior [NAS] male courtship behavior [IMP] adult locomotory behavior [IMP] oxidation reduction [IEA] catecholamine metabolic process [NAS]
Molecular Function:	iron ion binding [IEA] tyrosine 3-monooxygenase activity [ISS][NAS][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMAVAAAQKN REMFAIKKSY SIENGYPSRR RSLVDDARFE TLVVKQTKQT VLEEARSKAN  60
   61 DDSLEDCIVQ AQEHIPSEQD VELQDEHANL ENLPLEEYVP VEEDVEFESV EQEQSESQSQ 120
  121 EPEGNQQPTK NDYGLTEDEI LLANAASESS DAEAAMQSAA LVVRLKEGIS SLGRILKAIE 180
  181 TFHGTVQHVE SRQSRVEGVD HDVLIKLDMT RGNLLQLIRS LRQSGSFSSM NLMADNNLNV 240
  241 KAPWFPKHAS ELDNCNHLMT KYEPDLDMNH PGFADKVYRQ RRKEIAEIAF AYKYGDPIPF 300
  301 IDYSDVEVKT WRSVFKTVQD LAPKHACAEY RAAFQKLQDE QIFVETRLPQ LQEMSDFLRK 360
  361 NTGFSLRPAA GLLTARDFLA SLAFRIFQST QYVRHVNSPY HTPEPDSIHE LLGHMPLLAD 420
  421 PSFAQFSQEI GLASLGASDE EIEKLSTVYW FTVEFGLCKE HGQIKAYGAG LLSSYGELLH 480
  481 AISDKCEHRA FEPASTAVQP YQDQEYQPIY YVAESFEDAK DKFRRWVSTM SRPFEVRFNP 540
  541 HTERVEVLDS VDKLETLVHQ MNTEILHLTN AISKLRRPF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: ple-PB, FBpp0311654

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: