Protein Overview: Glu-RI-PA

General Information:
Name(s) found:	Glu-RI-PA / FBpp0076691 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|68067727\|sp\|Q03445.2\|GLK1_DROME RecName: Full=Glutamate receptor 1; AltName: Full=Glutamate receptor I; AltName: Full=dGLUR-I; AltName: Full=Kainate-selective glutamate receptor; Flags: Precursor [NCBI NR] gi\|23094076\|gb\|AAF50652.2\| glutamate receptor I [Drosophila melanogaster] [NCBI NR] gi\|211938491\|gb\|ACJ13142.1\| FI02103p [Drosophila melanogaster] [NCBI NR] gi\|17136702\|ref\|NP_476855.1\| glutamate receptor I [Drosophila melanogaster] [NCBI NR] Glutamate receptor 1 OS=Drosophila melanogaster GN=GluRIA PE=2 SV=2 [Swiss-Prot] Glutamate receptor 1 OS=Drosophila melanogaster GN=Glu-RI PE=2 SV=2 [Swiss-Prot] The gene Glutamate receptor I is referred to in FlyBase by the symbol Dmel\Glu-RI (CG8442, FBgn0004619). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:6617134..6628166. It has the cytological map location 65C1. There is experimental evidence that it has the molecular function</span>: alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG8442-PA translation from_gene[CG8442 Glu-RI FBgn0004619] seq_release:3 mol_weight=111669 cds_boundaries:(3L:6,584,099..6,594,289[+]) aa_length:991 transcript_info:[CG8442-RA seq_release:3] gene_info:[gene symbol:Glu-RI FBgn0004619 gene_boundaries:(3 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VRX9) CG8442 protein [DrosMelano7227.FASTAC.txt] CG8442-PA [Drosophila melanogaster]gi\|17136702\|ref\|NP_476855.1\| CG8442-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(6617670..6617796,6619521..6619673,6620031..6620158,6621976..6622105,6624401..6624654,6624967..6625152,6625241..6625480,6625689..6626049,6626173..6626435,6626500..6626958,6627022..6627266,6627367..6627760,6627828..6627863); ID=FBp [fly-100309-contam.fasta] Glutamate receptor 1 precursor (Glutamate receptor I) (dGLUR-I) (Kainate-selective glutamate receptor) [nr-271106-contam.fasta] Glutamate receptor I CG8442-PA [Drosophila melanogaster] [nr-271106-contam.fasta] CG8442-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(6617670..6617796,6619521..6619673,6620031..6620158,6621976..6622105,6624401..6624654,6624967..6625152,6625241..6625480,6625689..6626049,6626173..6626435,6626500..6626958,6627022..6627266,6627367..6627760,6627828..6627863); ID=FBpp0076691; name=Glu-RI-PA; parent=FBgn0004619,FBtr0076982; dbxref=FlyBase:FBpp0076691,FlyBase_Annotation_IDs:CG8442-PA,GB_protein:AAF50652.2,REFSEQ:NP_476855,GB_protein:AAF50652; MD5=5b8e8bec7540c3fe052e81c2f9a8eef9; length=991; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(6617670..6617796,6619521..6619673,6620031..6620158,6621976..6622105,6624401..6624654,6624967..6625152,6625241..6625480,6625689..6626049,6626173..6626435,6626500..6626958,6627022..6627266,6627367..6627760,6627828..6627863); ID=FBpp0076691; name=Glu-RI-PA; parent=FBgn0004619,FBtr0076982; dbxref=FlyBase:FBpp0076691,FlyBase_Annotation_IDs:CG8442-PA,GB_protein:AAF50652.2,REFSEQ:NP_476855,GB_protein:AAF50652; MD5=5b8e8bec7540c3fe052e81c2f9a8eef9; length=991; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:join(6617670..6617796,6619521..6619673,6620031..6620158,6621976..6622105,6624401..6624654,6624967..6625152,6625241..6625480,6625689..6626049,6626173..6626435,6626500..6626958,6627022..6627266,6627367..6627760,6627828..6627863); ID=FBpp0076691; name=Glu-RI-PA; parent=FBgn0004619,FBtr0076982; dbxref=FlyBase:FBpp0076691,FlyBase_Annotation_IDs:CG8442-PA,GB_protein:AAF50652.2,REFSEQ:NP_476855,GB_protein:AAF50652,FlyMine:FBpp0076691,modMine:FBpp0076691; MD5=5b8e8bec7540c3fe052e81c2f9a8eef9; length=991; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(6624570..6624696,6626421..6626573,6626931..6627058,6628876..6629005,6631301..6631554,6631867..6632052,6632141..6632380,6632589..6632949,6633073..6633335,6633400..6633858,6633922..6634166,6634267..6634660,6634728..6634763); ID=FBpp0076691; name=GluRIA-PA; parent=FBgn0004619,FBtr0076982; dbxref=FlyBase:FBpp0076691,FlyBase_Annotation_IDs:CG8442-PA,GB_protein:AAF50652.2,REFSEQ:NP_476855,GB_protein:AAF50652,FlyMine:FBpp0076691,modMine:FBpp0076691; MD5=5b8e8bec7540c3fe052e81c2f9a8eef9; length=991; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(6624570..6624696,6626421..6626573,6626931..6627058,6628876..6629005,6631301..6631554,6631867..6632052,6632141..6632380,6632589..6632949,6633073..6633335,6633400..6633858,6633922..6634166,6634267..6634660,6634728..6634763); ID=FBpp0076691; name=GluRIA-PA; parent=FBgn0004619,FBtr0076982; dbxref=FlyBase:FBpp0076691,FlyBase_Annotation_IDs:CG8442-PA,GB_protein:AAF50652.2,REFSEQ:NP_476855,GB_protein:AAF50652,FlyMine:FBpp0076691,modMine:FBpp0076691; MD5=5b8e8bec7540c3fe052e81c2f9a8eef9; length=991; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0076691 type=protein; loc=3L:join(6624570..6624696,6626421..6626573,6626931..6627058,6628876..6629005,6631301..6631554,6631867..6632052,6632141..6632380,6632589..6632949,6633073..6633335,6633400..6633858,6633922..6634166,6634267..6634660,6634728..6634763); ID=FBpp0076691; name=GluRIA-PA; parent=FBgn0004619,FBtr0076982; dbxref=FlyBase:FBpp0076691,FlyBase_Annotation_IDs:CG8442-PA,GB_protein:AAF50652.2,REFSEQ:NP_476855,GB_protein:AAF50652,FlyMine:FBpp0076691,modMine:FBpp0076691; MD5=5b8e8bec7540c3fe052e81c2f9a8eef9; length=991; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(6624570..6624696,6626421..6626573,6626931..6627058,6628876..6629005,6631301..6631554,6631867..6632052,6632141..6632380,6632589..6632949,6633073..6633335,6633400..6633858,6633922..6634166,6634267..6634660,6634728..6634763); ID=FBpp0076691; name=GluRIA-PA; parent=FBgn0004619,FBtr0076982; dbxref=FlyBase:FBpp0076691,FlyBase_Annotation_IDs:CG8442-PA,GB_protein:AAF50652.2,REFSEQ:NP_476855,GB_protein:AAF50652,UniProt/Swiss-Prot:Q03445,FlyMine:FBpp0076691,modMine:FBpp0076691; MD5=5b8e8bec7540c3fe052e81c2f9a8eef9; length=991; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	991 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [NAS] plasma membrane [ISS]
Biological Process:	NONE FOUND
Molecular Function:	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [IDA] extracellular-glutamate-gated ion channel activity [IEA][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSRLKFLAY LHFICASSIF WPEFSSAQQQ QQTVSLTEKI PLGAIFEQGT DDVQSAFKYA  60
   61 MLNHNLNVSS RRFELQAYVD VINTADAFKL SRLICNQFSR GVYSMLGAVS PDSFDTLHSY 120
  121 SNTFQMPFVT PWFPEKVLAP SSGLLDFAIS MRPDYHQAII DTIQYYGWQS IIYLYDSHDG 180
  181 LLRLQQIYQE LKPGNETFRV QMVKRIANVT MAIEFLHTLE DLGRFSKKRI VLDCPAEMAK 240
  241 EIIVQHVRDI KLGRRTYHYL LSGLVMDNHW PSDVVEFGAI NITGFRIVDS NRRAVRDFHD 300
  301 SRKRLEPSGQ SQSQNAGGPN SLPAISAQAA LMYDAVFVLV EAFNRILRKK PDQFRSNHLQ 360
  361 RRSHGGSSSS SATGTNESSA LLDCNTSKGW VTPWEQGEKI SRVLRKVEID GLSGEIRFDE 420
  421 DGRRINYTLH VVEMSVNSTL QQVAEWRDDA GLLPLHSHNY ASSSRSASAS TGDYDRNHTY 480
  481 IVSSLLEEPY LSLKQYTYGE SLVGNDRFEG YCKDLADMLA AQLGIKYEIR LVQDGNYGAE 540
  541 NQYAPGGWDG MVGELIRKEA DIAISAMTIT AERERVIDFS KPFMTLGISI MIKKPVKQTP 600
  601 GVFSFLNPLS QEIWISVILS YVGVSFVLYF VTRFPPYEWR IVRRPQADST AQQPPGIIGG 660
  661 ATLSEPQAHV PPVPPNEFTM LNSFWYSLAA FMQQGCDITP PSIAGRIAAA VWWFFTIILI 720
  721 SSYTANLAAF LTVERMVAPI KTPEDLTMQT DVNYGTLLYG STWEFFRRSQ IGLHNKMWEY 780
  781 MNANQHHSVH TYDEGIRRVR QSKGKYALLV ESPKNEYVNA RPPCDTMKVG RNIDTKGFGV 840
  841 ATPIGSPLRK RLNEAVLTLK ENGELLRIRN KWWFDKTECN LDQETSTPNE LSLSNVAGIY 900
  901 YILIGGLLLA VIVAIMEFFC RNKTPQLKSP GSNGSAGGVP GMLASSTYQR DSLSDAIMHS 960
  961 QAKLAMQASS EYDERLVGVE LASNVRYQYS M

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Glu-RI-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: