Protein Overview: NT1-PC, NT1-PB, ...

General Information:
Name(s) found:	NT1-PE / FBpp0290735 [FlyBase] NT1-PC / FBpp0290733 [FlyBase] NT1-PB / FBpp0290732 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24657793\|ref\|NP_729011.1\| CG32244, isoform C [Drosophila melanogaster] [NCBI NR] gi\|24657785\|ref\|NP_729010.1\| CG32244, isoform B [Drosophila melanogaster] [NCBI NR] gi\|23093018\|gb\|AAN11607.1\| CG32244, isoform C [Drosophila melanogaster] [NCBI NR] gi\|23093017\|gb\|AAN11606.1\| CG32244, isoform B [Drosophila melanogaster] [NCBI NR] gi\|220790500\|tpg\|DAA06448.1\| TPA_exp: neurotrophin 1 short isoform [Drosophila melanogaster] [NCBI NR] gi\|220790498\|tpg\|DAA06447.1\| TPA_exp: neurotrophin 1 short isoform [Drosophila melanogaster] [NCBI NR] gi\|203287127\|gb\|ACH98105.1\| neurotrophin 1 short isoform [Drosophila melanogaster] [NCBI NR] The gene Neurotrophin 1 is referred to in FlyBase by the symbol Dmel\NT1 (CG42576, FBgn0261526). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4501652..4508429. It has the cytological map location 64B9. There is experimental evidence that it has the molecular function</span>: growth factor activity. There is experimental evidence that it is involved in the biological process</span>: motor axon guidance; regulation of cell death; axon guidance; nervous system development; regulation of neuronal synaptic plasticity in response to neurotrophin; central nervous system formation; regulation of neuron apoptosis. 13 alleles are reported. The phenotypes of these alleles are annotated with: segmental nerve; SNa; motor neuron; ISNb; embryonic nervous system; ISNd. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] >CG32244-PB translation from_gene[CG32244 CG32244 FBgn0052244] seq_release:3 mol_weight=50904 cds_boundaries:(3L:4,482,344..4,483,796[-]) aa_length:454 transcript_info:[CG32244-RB seq_release:3] gene_info:[gene symbol:CG32244 synonyms:[CG18318] FBgn005 [hmr_yeast5_DM3-1_pombe.fasta] >CG32244-PC translation from_gene[CG32244 CG32244 FBgn0052244] seq_release:3 mol_weight=50904 cds_boundaries:(3L:4,482,344..4,483,796[-]) aa_length:454 transcript_info:[CG32244-RC seq_release:3] gene_info:[gene symbol:CG32244 synonyms:[CG18318] FBgn005 [hmr_yeast5_DM3-1_pombe.fasta] (Q8IRB0) CG32244-PB [DrosMelano7227.FASTAC.txt] CG32244-PC, isoform C [Drosophila melanogaster]gi\|23093017\|gb\|AAN11606.1\| CG32244-PB, isoform B [Drosophila melanogaster]gi\|24657793\|ref\|NP_729011.1\| CG32244-PC [Drosophila melanogaster]gi\|24657785\|ref\|NP_729010.1\| CG32244-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0073180; name=CG32244-PB; parent=FBgn0052244,FBtr0073324; dbxref=FlyBase:FBpp0073180,FlyBase_Annotation_IDs:CG32244-PB,GB_protein:AAN11606.1,REFSEQ:NP_729010,GB_protein:AAN11606; M [fly-100309-contam.fasta] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0073181; name=CG32244-PC; parent=FBgn0052244,FBtr0073325; dbxref=FlyBase:FBpp0073181,FlyBase_Annotation_IDs:CG32244-PC,GB_protein:AAN11607.1,REFSEQ:NP_729011,GB_protein:AAN11607; M [fly-100309-contam.fasta] CG32244-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta] CG32244-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0073180; name=CG32244-PB; parent=FBgn0052244,FBtr0073324; dbxref=FlyBase:FBpp0073180,FlyBase_Annotation_IDs:CG32244-PB,GB_protein:AAN11606.1,REFSEQ:NP_729010,GB_protein:AAN11606; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0073181; name=CG32244-PC; parent=FBgn0052244,FBtr0073325; dbxref=FlyBase:FBpp0073181,FlyBase_Annotation_IDs:CG32244-PC,GB_protein:AAN11607.1,REFSEQ:NP_729011,GB_protein:AAN11607; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0290732; name=spz2-PB; parent=FBgn0260984,FBtr0301517; dbxref=FlyBase_Annotation_IDs:CG42576-PB,FlyBase:FBpp0290732,FlyBase:FBpp0073180,FlyBase_Annotation_IDs:CG32244-PB; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0290733; name=spz2-PC; parent=FBgn0260984,FBtr0301518; dbxref=FlyBase_Annotation_IDs:CG42576-PC,FlyBase:FBpp0290733,FlyBase:FBpp0073181,FlyBase_Annotation_IDs:CG32244-PC; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0290735; name=spz2-PE; parent=FBgn0260984,FBtr0301520; dbxref=FlyBase_Annotation_IDs:CG42576-PE,FlyBase:FBpp0290735; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] FI02176p OS=Drosophila melanogaster GN=NT1 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0290733; name=NT1-PC; parent=FBgn0261526,FBtr0301518; dbxref=REFSEQ:NP_729011,GB_protein:AAN11607,FlyBase_Annotation_IDs:CG42576-PC,FlyBase:FBpp0290733,FlyBase:FBpp0073181,FlyBase_Annotation_IDs:CG32244-PC,FlyMine:FBpp0290733,modMine:FBpp0290733; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0290732; name=NT1-PB; parent=FBgn0261526,FBtr0301517; dbxref=REFSEQ:NP_729010,GB_protein:AAN11606,FlyBase_Annotation_IDs:CG42576-PB,FlyBase:FBpp0290732,FlyBase:FBpp0073180,FlyBase_Annotation_IDs:CG32244-PB; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(4504400..4505308,4505400..4505855); ID=FBpp0290735; name=NT1-PE; parent=FBgn0261526,FBtr0301520; dbxref=REFSEQ:NP_001163349,GB_protein:ACZ94621,FlyBase_Annotation_IDs:CG42576-PE,FlyBase:FBpp0290735; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] FI02176p OS=Drosophila melanogaster GN=NT1 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290733; name=NT1-PC; parent=FBgn0261526,FBtr0301518; dbxref=REFSEQ:NP_729011,GB_protein:AAN11607,FlyBase_Annotation_IDs:CG42576-PC,FlyBase:FBpp0290733,FlyBase:FBpp0073181,FlyBase_Annotation_IDs:CG32244-PC,FlyMine:FBpp0290733,modMine:FBpp0290733; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290732; name=NT1-PB; parent=FBgn0261526,FBtr0301517; dbxref=REFSEQ:NP_729010,GB_protein:AAN11606,FlyBase_Annotation_IDs:CG42576-PB,FlyBase:FBpp0290732,FlyBase:FBpp0073180,FlyBase_Annotation_IDs:CG32244-PB; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290735; name=NT1-PE; parent=FBgn0261526,FBtr0301520; dbxref=REFSEQ:NP_001163349,GB_protein:ACZ94621,FlyBase_Annotation_IDs:CG42576-PE,FlyBase:FBpp0290735; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290733; name=NT1-PC; parent=FBgn0261526,FBtr0301518; dbxref=REFSEQ:NP_729011,GB_protein:AAN11607,FlyBase_Annotation_IDs:CG42576-PC,FlyBase:FBpp0290733,FlyBase:FBpp0073181,FlyBase_Annotation_IDs:CG32244-PC,FlyMine:FBpp0290733,modMine:FBpp0290733; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290732; name=NT1-PB; parent=FBgn0261526,FBtr0301517; dbxref=REFSEQ:NP_729010,GB_protein:AAN11606,FlyBase_Annotation_IDs:CG42576-PB,FlyBase:FBpp0290732,FlyBase:FBpp0073180,FlyBase_Annotation_IDs:CG32244-PB; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290735; name=NT1-PE; parent=FBgn0261526,FBtr0301520; dbxref=REFSEQ:NP_001163349,GB_protein:ACZ94621,FlyBase_Annotation_IDs:CG42576-PE,FlyBase:FBpp0290735; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q9VZA9, FI02176p OS=Drosophila melanogaster GN=NT1 PE=2 SV=1 [DROME.fasta.20160308] FBpp0290733 type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290733; name=NT1-PC; parent=FBgn0261526,FBtr0301518; dbxref=REFSEQ:NP_729011,GB_protein:AAN11607,FlyBase_Annotation_IDs:CG42576-PC,FlyBase:FBpp0290733,FlyBase:FBpp0073181,FlyBase_Annotation_IDs:CG32244-PC,FlyMine:FBpp0290733,modMine:FBpp0290733; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0290732 type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290732; name=NT1-PB; parent=FBgn0261526,FBtr0301517; dbxref=REFSEQ:NP_729010,GB_protein:AAN11606,FlyBase_Annotation_IDs:CG42576-PB,FlyBase:FBpp0290732,FlyBase:FBpp0073180,FlyBase_Annotation_IDs:CG32244-PB; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0290735 type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290735; name=NT1-PE; parent=FBgn0261526,FBtr0301520; dbxref=REFSEQ:NP_001163349,GB_protein:ACZ94621,FlyBase_Annotation_IDs:CG42576-PE,FlyBase:FBpp0290735; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290733; name=NT1-PC; parent=FBgn0261526,FBtr0301518; dbxref=REFSEQ:NP_729011,GB_protein:AAN11607,FlyBase_Annotation_IDs:CG42576-PC,FlyBase:FBpp0290733,FlyBase:FBpp0073181,FlyBase_Annotation_IDs:CG32244-PC,UniProt/TrEMBL:Q8IRB0,FlyMine:FBpp0290733,modMine:FBpp0290733; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290732; name=NT1-PB; parent=FBgn0261526,FBtr0301517; dbxref=REFSEQ:NP_729010,GB_protein:AAN11606,FlyBase_Annotation_IDs:CG42576-PB,FlyBase:FBpp0290732,FlyBase:FBpp0073180,FlyBase_Annotation_IDs:CG32244-PB,UniProt/TrEMBL:Q8IRB0; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3L:complement(join(4505400..4505855,4504400..4505308)); ID=FBpp0290735; name=NT1-PE; parent=FBgn0261526,FBtr0301520; dbxref=REFSEQ:NP_001163349,GB_protein:ACZ94621,FlyBase_Annotation_IDs:CG42576-PE,FlyBase:FBpp0290735,UniProt/TrEMBL:Q8IRB0; MD5=46c4dc752a3956ab3877c6b70547bc38; length=454; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	454 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	regulation of neuronal synaptic plasticity in response to neurotrophin [IMP] motor axon guidance [IMP] nervous system development [IMP] regulation of cell death [IDA] axon guidance [IMP] central nervous system formation [IMP] regulation of neuron apoptosis [IMP]
Molecular Function:	growth factor activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAGRAFGCL FWALLYCVLY LDLVSGNSAD DELMDFDFAD SNDAAMEDWQ LDDLEEAKKA  60
   61 EQAEKKLESN MLDFSVDLDE PEPEKQLPPF DWRERVLRNA LAKALADEGL RQKFAEVLPI 120
  121 LRMLSSQQRL ALSALISAQM NAKKGHELKF EQVRMMFGNE KKLLLPIVFD IANLIKSSTR 180
  181 KYINLGSDLA SSALYHTPIN RREDDLTPEE SQQDDQLGTI AVEVEPKKVS TEEVQLESLE 240
  241 DFFDEMGSEV LDPQMINEAL TGDLHDNKTK TFKPENHGQR VRRSANEFVH KLTRSVPASV 300
  301 TEQQLLGGIA GRTIKLNTTA FQQPSSQEEE KMASSNGGQS YSEVEDLAFA GLNGTEIPLS 360
  361 ADERLDLQRN SAEETEEPLP SPEELIAGPR YRLGKRPLPG QKSGSPIKRK RVTSSLRGRP 420
  421 KTAASSHKPV VTPPNKKCER FTSNMCIRTD DYPL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: NT1-PC, NT1-PB, ...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: