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Protein Overview: FBpp0292863, kst-PA

General Information:
Name(s) found: FBpp0292863 [FlyBase]
kst-PA / FBpp0072934 [FlyBase]
Description(s) found:
Found 27 descriptions.
SHOW ALL
  • type=protein; loc=3L:join(3351567..3351686,3351965..3352132,3353738..3353854,3353923..3354185,3354255..3354384,3354637..3354824,3354949..3357922,3357982..3358121,3358179..3359789,3359853..3365751,3365811..3366126,3366200..3366310,3367515..3367771); ID=FBpp0292863; name=kst-PF; parent=FBgn0004167,FBtr0303857; dbxref=FlyBase:FBpp0292863,FlyBase_Annotation_IDs:CG12008-PF,REFSEQ:NP_001189041,GB_protein:ADV37478; MD5=df15408e83aef28e8fa68c13534f49e6; length=4097; release=r5.56; species=Dmel; [FlyBase]
  • The gene karst is referred to in FlyBase by the symbol Dmel\kst (CG12008, FBgn0004167). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3337103..3368133. It has the cytological map location 63D2. There is experimental evidence that it has the molecular function</span>: actin binding; microtubule binding. There is experimental evidence that it is involved in the biological process</span>: cytokinesis. 16 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; female germline cyst; external compound sense organ; peripheral nervous system; follicle cell; nervous system; compound cell cluster organ; adult; adult tracheal system; adult segment. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 4097 amino acids

    Gene Ontology:
    Cellular Component: apicolateral plasma membrane [TAS]
    spectrin [ISS]
    Biological Process: plasma membrane organization [TAS]
    ovarian follicle cell development [TAS]
    zonula adherens assembly [TAS]
    cytokinesis [IMP]
    Molecular Function: actin binding [IDA][ISS]
    cytoskeletal protein binding [ISS]
    microtubule binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQRDGIIKF ENERIKTLQE ERLHIQKKTF TKWMNSFLIK AKMEVEDLFT DLADGIKLLK  60
   61 LLEIISSEKL GKPNSGRMRV HKIENVNKSL AFLHTKVRLE SIGAEDIVDG NPRLILGLIW 120
  121 TIILRFQIQE IEIDVDEENE SSEKRSAKDA LLLWCQRKTH GYPGVNITDF TNSWRSGLGF 180
  181 NALIHSHRPD LFEYSTIVNS KNSNLDNLNH AFDTAANELG IPSLLDAEDI DSARPDEKSI 240
  241 LTYVASYYHT FARMKNEQKS GKRIANIVGQ LMDADRKKMQ YEGLTTNLLS WIRQKTLELE 300
  301 QRDLPNSLEG IQRELLAFKE YRTIEKPPKY KERSEIEALY FTINTLLKAL NQPPYNPQDG 360
  361 QLVNDIEKAW QILEYAEHHR EVALRDELLR QEKLEQLNYK FEKKSVLREG YLKEMIQVLS 420
  421 DPRYLRQVDA TLKKHEAISA DILARVERFN DLTAMAEELD RENYHGKERV RRREQEVMAK 480
  481 WRQLLELLEN QRLNLSQMSN LMNLLREIAS TTEAVRELQQ QFASEDVGPH LLGVEELLQA 540
  541 HSLQELQVNT YGETLKRFNR QALPYKSSEH KDAALLAQRL ADLEEAYSEL LRRSAARRAR 600
  601 LEEARNFHHF MEDYDNEESW LVDKQRICKT GITAKDLRAV LSLQQKHKAL EDEIKSRKPK 660
  661 SGQMSTAGKR LIGEQHPRSS EIQSRIDSLA EHWQALEALV ELRRRQLEDA AEAYQFYTDA 720
  721 NEAESWLNEK IALVNSRDYG NDEPSAQALL QRHRDLQGEL NAYSGDILNL NQQADKLIKA 780
  781 GICTLELSAA EPELPEVEQE EWVNETRLVP KEVWEDEWVE KLEHKKVTET KMLPHVKSLF 840
  841 PFEGQGMKMD KGEVMLLKSK TNDDWWCVRK DNGVEGFVPA NYVREVEPRP VACIVPKAEK 900
  901 VKSLQKVKKT ILVRQVVPVK RIKPVSVAPK PLVQRRTSTQ SINENADSVE KRQQRINQTY 960
  961 DELQEMAQKR HALLEDSIHL FGFYRECDDF EKWMKEKERM IKSDEGEGVD NAKRKFEKFI1020
 1021 TDLSAASKRV EEIDGAVDTF RRQGHSQLDK IIARQRQIHQ IWQRLNNAKA QREKSLEGAS1080
 1081 SVELFNRTCD EAKVWMSEKM LQLDTAVITP DLRTVQALQR RHQNLERELA PVEDKVNRVT1140
 1141 YLGNSVKNAY PAEKDNVNAR QQEVQDMWQQ VQQRGSDLRN RIESEVGQQV FNNSAKVLLA1200
 1201 WIDSVKDQLN ADESARDVET ANNLLKKHND LGDDIRAHDT EFVEVIQLGK QLSDGKPNMA1260
 1261 ETVAVIERLK AEQDAIHRGW AEKQKWLLQC VDLQMFNREA DKIDATTKSH EAFLEYNNLG1320
 1321 ASLDEVEAIL KRHLDFEKSL MAQDKILKGF SDNADKLISN DHYDSKYIGD RRNQVLGKRK1380
 1381 AVKDRAFERK RLLQASKDFH KFAAEADDLK VWLQDKTRIA GDENYRDLSN LPRKLQKHQA1440
 1441 FERELRANEG QLRNVTKDGQ ALVQAGNRVP EVESRVADLN KRWKDLLTLS EDKGRKLEQA1500
 1501 ASQREHNRSL EDAKKKVDEL DSALRSGDVG NDLRSCKDLI NKQQILESEI TIWDQKVAEL1560
 1561 VSTGDDMAHG GHFNAQNIEA GTKELQQRFK DLRDPTQRRR AKLEESLNYH KFVFELDSEF1620
 1621 QWINEHLPAA KSNELGQNLH QAQSLHKKHK KLEAEIKGHQ PMINKALVAG QSLISQQHPE1680
 1681 REQVESLCQQ LEQAWQDLER HCGERSRKLD MSLKAQQYLF DAGEIESWLG ERNNVLRSTE1740
 1741 YGRDRDSAAK LLTKHKTIEL ELDTYSGIVT EMGHSCAAMV AANHPDSKVL AAKQQLIEKM1800
 1801 LKSLHKLASQ RQGRLMESLY KHEYFLESDE VEQWIREQEQ AASSEDYGQD FEHLQLLQNK1860
 1861 FDDLKHRVEV GADRVDQCEL LAKKLIDSES PYANEVEKRQ EQLRTSWENL LQLLNQREQK1920
 1921 LHAAGEIHRF HRDVAEALFR IQDKNAALSQ ELGRDLNSAL ALLRKHEGFE NDLVALEAQL1980
 1981 QVLVEDSVRL QAKYPSNASA IAQQQDKVVA AWNDLKERST ARGDRLAASS DLQTFLTDVR2040
 2041 DIVSWSSNLR AALQAEEHVS DAAGATALKI QHDAIYGEIE AREDKFRYLN ELSDSMVQTG2100
 2101 HYAAADVEEK CAAMLDERQK LHAAWNKKKI MLEQKIDLFC FLRDAKQIDN LSSSQQAALS2160
 2161 SSDFGQTVED VQNKIRKHDE FERLIQTQEE KVSLLQEHGR KLIEQRHYDS ANIQTILQGV2220
 2221 LARRQKVKDL CAVRRYKLED ALLYAKFVRD CAEAKYWINE KQKKLEADAA SYAEVTNLDE2280
 2281 KIKKLQKHQA FQAEVAANQG RIQEIQDTGV ILLSKQHESS PEIKRAIEIV LEAWQGLLAE2340
 2341 LEQRGRGLEE AQDSLEFNSQ LDKIEAWIRD KEMMVQASDT GRDLEHCNAL MRKLDDVDSD2400
 2401 MRVDDQRVKH INQLADKLIN QAQVPADTQS VDKRRKDFNY NWRQLQGALN AYRALLGGAN2460
 2461 EIHVFNRDVD DTADRIAEKS LAMSSTDTGR DLAAVEALIR REEALERDMS AVKQKIDQHE2520
 2521 TAAEFLIKKY PERGAQHIER KLEELHKSWG NLQALSVKRQ SILNEAYLAH KFVSDVKELE2580
 2581 LWVNDMIKKM NNTQSPSTIN DCETQLELHQ ERKVEIEGRQ EAFAGLKQQG EQLSKRPQQQ2640
 2641 QPDNVRKYLL VLEELHQTLN EAWSERARDL TEAHQLQLFK AQVEQVEIWL ANKEAFLNND2700
 2701 DLGDSYTAVE RLLKKHDEFE KLLHADHVDT LQKFANSILE GEPKDADLIR EKLAYILRRK2760
 2761 QKLLELSEER KQRLTQSHQL QEFLRSLYEI DRWLVQKLQV ALDENYREPS NLQSKIQKHA2820
 2821 AFDAELLSNS PRVQSVIHEG ERLIRGDHFA KDEIAQQVQL LEGDWLKLKG ASQTKKDKLQ2880
 2881 QAYDALAFNR SVDEFNNWMD EVELQLSSED YGKDLAAVSN LLKKHERLEA DVAHHGELAD2940
 2941 QLKQKDEQFF QAEHFLRHEI HERATVSIRR YNTLHEPLGI RRENLEDSLS LQQFLRDAED3000
 3001 ELQWLAEKQL VAGSQDLGTS LLSVQGLQKK HNSLEAELTS QEPLIQALLQ RGQQMIRDNH3060
 3061 FASEQLQYKS ELLQKQLVQL RDLAAIRRLR LLDAVESQLF YVEANEADAW MREKRPVLSS3120
 3121 SDYGRDEVSV QGHQKKLEVL QRELTAFKPS IEKVAKLATG LIERNHFDSS NIAEKNAQVG3180
 3181 QEYEDLLRLA KERESRLGEC KKLFEYLRET EELHEWVGDQ MAVTASEDYG EDVEHVEQLI3240
 3241 LAFESFVSNL NANEARVEAC LERGDRLIQE NNPYRSSIKS KRDETKQLWE ELKDLVHARQ3300
 3301 DALAGAKQVH VYDRVADETI QLINEKDASL ISEDYGQDLE SIQALGRKHQ VFESELVGIQ3360
 3361 GQVDSVLAEA AKLGEIYPDA KEHIEVKRDE TVEAWTDLKE KTAARKNKLS QAEQLQSYFD3420
 3421 EYRDLIAWIN EMLAKITAPE LANSVAGAEL LLASTKDHDT EIRTRDETFA KFAANGQQLI3480
 3481 KEKHFLAHEV EDKIKVLQAR HELLKHTLNK RREIYELNLD TQLFLKDAEI LEQWISSREP3540
 3541 QLKDTKLGDS IPQVEDLLRR HEDFEKTVAA QEEKFQAIKR ITMLEQLFRH QLEQEKISKL3600
 3601 QEKERLEKER LEQLKQRELQ RLADERRRAE KQHEHRQNAA SQEKTPIFSS PMVTPAQTSG3660
 3661 PQSPALSQVQ LRPPFGDDNE HLALQKSSSS GMFGDRLRRG SADANVKRAE SMKVQPKQAK3720
 3721 RTPSFTTRRR AQSFRKNQKG EGFDLPPVEI QGSLERKHGL QSGGKKAPVR SWKQFHTVLC3780
 3781 GQLVCFFKDE NDFLQQKTAT APVNILGAKC ERADDYTKKK YVFRLKLPDG SEFLFEAPSL3840
 3841 DILNDWVRKI SFHASLPPNM QLLSYDESMK QQSSSSPDIK VTSSVESPVS SRNSSPDSQR3900
 3901 RTSGAQVLDG TATPQMAFLQ RQMQQQQQQQ QSQPSSPTGG FDQKPPIPPR GAAPVASHRQ3960
 3961 SQENLVVMRN RQSSNDLQQS ATLPAGLTGV QQNGNGKDDN ALLTRNSEAR QSGWGNTRFE4020
 4021 SNRPVSLQPD SISFSRVSAE SSSESEAQSI SSVSGVKGSK GTKEERRSGM FRIFGRKGDK4080
 4081 EKEKDKDKRR SSQVPPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle