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Protein Overview: FBpp0292309, Sac1-PA

General Information:
Name(s) found: FBpp0292309 [FlyBase]
Sac1-PA / FBpp0072546 [FlyBase]
Description(s) found:
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  • gi|74948853|sp|Q9W0I6.1|SAC1_DROME RecName: Full=Phosphatidylinositide phosphatase SAC1; AltName: Full=Suppressor of actin mutations 1-like protein [NCBI NR]
  • gi|7292047|gb|AAF47460.1| Sac1 [Drosophila melanogaster] [NCBI NR]
  • gi|19923034|ref|NP_612087.1| Sac1 [Drosophila melanogaster] [NCBI NR]
  • gi|15010510|gb|AAK77303.1| GH08349p [Drosophila melanogaster] [NCBI NR]
  • Phosphatidylinositide phosphatase SAC1 OS=Drosophila melanogaster GN=Sac1 PE=2 SV=1 [Swiss-Prot]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0292309; name=Sac1-PB; parent=FBgn0035195,FBtr0303217; dbxref=FlyBase:FBpp0292309,FlyBase_Annotation_IDs:CG9128-PB,REFSEQ:NP_001189016,GB_protein:ADV37453; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r5.56; species=Dmel; [FlyBase]
  • The gene Sac1 is referred to in FlyBase by the symbol Dmel\Sac1 (CG9128, FBgn0035195). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:1248019..1250456. It has the cytological map location 61F4. Based on sequence similarity, it is predicted to have molecular function</span>: polyphosphoinositide phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of JNK cascade; dorsal closure, amnioserosa morphology change. 8 alleles are reported. The phenotypes of these alleles are annotated with: amnioserosa; dorsal hair. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG9128-PA translation from_gene[CG9128 CG9128 FBgn0035195] seq_release:3 mol_weight=67768 cds_boundaries:(3L:1,228,920..1,230,695[+]) aa_length:592 transcript_info:[CG9128-RA seq_release:3] gene_info:[gene symbol:CG9128 FBgn0035195 gene_boundaries:(3L [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W0I6) CG9128 protein (GH08349P) [DrosMelano7227.FASTAC.txt]
  • (AE003471) CG9128 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG9128-PA [Drosophila melanogaster]gi|15010510|gb|AAK77303.1| GH08349p [Drosophila melanogaster]gi|19923034|ref|NP_612087.1| CG9128-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0072546; name=Sac1-PA; parent=FBgn0035195,FBtr0072652; dbxref=FlyBase:FBpp0072546,FlyBase_Annotation_IDs:CG9128-PA,GB_protein:AAF47460.1,REFSEQ:NP_612087,GB_protein:AAF47460; MD5=49d880a663fc764c57deb24f8f816a [fly-100309-contam.fasta]
  • CG9128-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Sac1 CG9128-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH08349p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0072546; name=Sac1-PA; parent=FBgn0035195,FBtr0072652; dbxref=FlyBase:FBpp0072546,FlyBase_Annotation_IDs:CG9128-PA,GB_protein:AAF47460.1,REFSEQ:NP_612087,GB_protein:AAF47460; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0072546; name=Sac1-PA; parent=FBgn0035195,FBtr0072652; dbxref=FlyBase:FBpp0072546,FlyBase_Annotation_IDs:CG9128-PA,GB_protein:AAF47460.1,REFSEQ:NP_612087,GB_protein:AAF47460; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Phosphatidylinositide phosphatase SAC1 OS=Drosophila melanogaster GN=Sac1 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0072546; name=Sac1-PA; parent=FBgn0035195,FBtr0072652; dbxref=FlyBase:FBpp0072546,FlyBase_Annotation_IDs:CG9128-PA,GB_protein:AAF47460.1,REFSEQ:NP_612087,GB_protein:AAF47460,FlyMine:FBpp0072546,modMine:FBpp0072546; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0292309; name=Sac1-PB; parent=FBgn0035195,FBtr0303217; dbxref=FlyBase:FBpp0292309,FlyBase_Annotation_IDs:CG9128-PB,REFSEQ:NP_001189016,GB_protein:ADV37453; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0072546; name=Sac1-PA; parent=FBgn0035195,FBtr0072652; dbxref=FlyBase:FBpp0072546,FlyBase_Annotation_IDs:CG9128-PA,GB_protein:AAF47460.1,REFSEQ:NP_612087,GB_protein:AAF47460,FlyMine:FBpp0072546,modMine:FBpp0072546; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0292309; name=Sac1-PB; parent=FBgn0035195,FBtr0303217; dbxref=FlyBase:FBpp0292309,FlyBase_Annotation_IDs:CG9128-PB,REFSEQ:NP_001189016,GB_protein:ADV37453; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0072546; name=Sac1-PA; parent=FBgn0035195,FBtr0072652; dbxref=FlyBase:FBpp0072546,FlyBase_Annotation_IDs:CG9128-PA,GB_protein:AAF47460.1,REFSEQ:NP_612087,GB_protein:AAF47460,FlyMine:FBpp0072546,modMine:FBpp0072546; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0292309; name=Sac1-PB; parent=FBgn0035195,FBtr0303217; dbxref=FlyBase:FBpp0292309,FlyBase_Annotation_IDs:CG9128-PB,REFSEQ:NP_001189016,GB_protein:ADV37453; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9W0I6, Sac1, isoform B OS=Drosophila melanogaster GN=Sac1 PE=4 SV=1 [DROME.fasta.20160308]
  • FBpp0072546 type=protein; loc=3L:1248291..1250069; ID=FBpp0072546; name=Sac1-PA; parent=FBgn0283500,FBtr0072652; dbxref=FlyBase:FBpp0072546,FlyBase_Annotation_IDs:CG9128-PA,GB_protein:AAF47460.1,REFSEQ:NP_612087,GB_protein:AAF47460,FlyMine:FBpp0072546,modMine:FBpp0072546; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0292309 type=protein; loc=3L:1248291..1250069; ID=FBpp0292309; name=Sac1-PB; parent=FBgn0283500,FBtr0303217; dbxref=FlyBase:FBpp0292309,FlyBase_Annotation_IDs:CG9128-PB,REFSEQ:NP_001189016,GB_protein:ADV37453; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0072546; name=Sac1-PA; parent=FBgn0283500,FBtr0072652; dbxref=FlyBase:FBpp0072546,FlyBase_Annotation_IDs:CG9128-PA,GB_protein:AAF47460.1,REFSEQ:NP_612087,GB_protein:AAF47460,UniProt/Swiss-Prot:Q9W0I6,FlyMine:FBpp0072546,modMine:FBpp0072546; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3L:1248291..1250069; ID=FBpp0292309; name=Sac1-PB; parent=FBgn0283500,FBtr0303217; dbxref=FlyBase:FBpp0292309,FlyBase_Annotation_IDs:CG9128-PB,REFSEQ:NP_001189016,GB_protein:ADV37453,UniProt/Swiss-Prot:Q9W0I6; MD5=49d880a663fc764c57deb24f8f816a01; length=592; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 592 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: dorsal closure, amnioserosa morphology change [IMP]
    negative regulation of JNK cascade [IGI][IMP]
    Molecular Function: polyphosphoinositide phosphatase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSREENAVY DDMNLYIAPQ SFIIEPNGGD ELLVIGRHDK VTRVQPASGG LVANLRPTRR  60
   61 ICGVLGTIHL LSCDYLLVAT HRLFVGVLNG AVVWRLAGYD IIPYIPNSFQ RKENENYLRL 120
  121 LRQTLDTKFF YFSYRYDLTN SLQRQREVAQ SRPEVSGLLQ RAEQRFVWNG YVLRQFNCDK 180
  181 MEKFQLPLVL GFVSINQVQI NGQTFFWSII TRRSVQRAGT RLFCRGSDEQ GHVANFVETE 240
  241 QIVEFNGQLT GFVQTRGSMP FHWHQLPNLR YKPRPVLVPG KDHLAACGLH FKEQIRLYGN 300
  301 NVAVNLVDHK GAEGELEATY ARLVREMGNP QVRYESFDFH SECRKMRWDR LNILIDRLAH 360
  361 EQDQFGVYHV FDDGKLVSTQ TGVFRTNCID CLDRTNVVQS MLARRSLTAV LQKLGVLHVG 420
  421 QKVEHASDIF ESIFKGVWAD NADLVSLQYS GTCALKTDFT RTGKRTKSGA MQDGKNSLMR 480
  481 YYLNNFADGQ RQDSIDLFLG KYLVNDNEGG AVPSPLESKH GWRFFTFPSV LLVAVAMFMI 540
  541 TMTYPAEFNT ENLLFMLFWG AMIAVSATGI LHYGVEFVQW PRLFPPISFR DP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle