Protein Overview: FBpp0305064, fwd...

General Information:
Name(s) found:	FBpp0305064 [FlyBase] fwd-PA / FBpp0072416 [FlyBase] fwd-PB / FBpp0072415 [FlyBase]
Description(s) found: Found 40 descriptions. SHOW ALL	type=protein; loc=3L:complement(306359..306546,306605..306769,306829..306917,306982..307256,307319..307456,307512..307630,307695..310178,310277..310465,310525..310786,311174..311285,313024..314027); ID=FBpp0305064; name=fwd-PD; parent=FBgn0004373,FBtr0332841; dbxref=REFSEQ:NP_001261203,GB_protein:AGB93898,FlyBase:FBpp0305064,FlyBase_Annotation_IDs:CG7004-PD; MD5=b814d840f3ba51d94b853af5df30c1d8; length=1674; release=r5.56; species=Dmel; [FlyBase] The gene four wheel drive is referred to in FlyBase by the symbol Dmel\fwd (CG7004, FBgn0004373). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:306207..319880. It has the cytological map location 61C1. Based on sequence similarity, it is predicted to have molecular function</span>: 1-phosphatidylinositol 4-kinase activity. There is experimental evidence that it is involved in the biological process</span>: male meiosis cytokinesis; contractile ring contraction involved in cytokinesis during cell cycle; testicular ring canal formation; determination of adult lifespan; meiotic spindle stabilization; cytokinesis after meiosis II; cytokinesis after meiosis I. 17 alleles are reported. The phenotypes of these alleles are annotated with: secondary spermatocyte; Nebenkern; Nebenkern derivative; spermatid; spermatid axoneme; spermatozoon. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene four wheel drive is referred to in FlyBase by the symbol Dmel\fwd (CG7004, FBgn0004373). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:306207..319880. It has the cytological map location 61C1. Based on sequence similarity, it is predicted to have molecular function</span>: 1-phosphatidylinositol 4-kinase activity. There is experimental evidence that it is involved in the biological process</span>: male meiosis cytokinesis; contractile ring contraction involved in cytokinesis during cell cycle; testicular ring canal formation; determination of adult lifespan; meiotic spindle stabilization; cytokinesis after meiosis II; cytokinesis after meiosis I. 17 alleles are reported. The phenotypes of these alleles are annotated with: secondary spermatocyte; Nebenkern; Nebenkern derivative; spermatid; spermatid axoneme; spermatozoon. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1674 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	contractile ring contraction involved in cell cycle cytokinesis [IMP] spermatocyte division [IMP] male germline ring canal formation [IMP] phosphoinositide-mediated signaling [IEA] cytokinesis after meiosis I [IMP] determination of adult lifespan [IMP] phosphoinositide phosphorylation [IEA] meiotic spindle stabilization [IMP] cytokinesis after meiosis II [IMP] male meiosis cytokinesis [IMP] phosphorylation [NAS]
Molecular Function:	1-phosphatidylinositol 4-kinase activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSVISAFKG KKNSNPSCNS PMGSANGTAP VEAKPNNCYQ YLRHIREIDT NNKLLSPVVV  60
   61 VAEERPVSKA GSPSTVATMA TGVDVVDHCL PTTVRLSVTE ALSDLNMNGK AVEPPVTPCT 120
  121 SVGDNANLEV AETWACPPPQ ATDDEDISEH STAACTSTSS SSEHSNSTVV HSPTVGESTC 180
  181 DSVSVSVSHP SPSVSQNNTS SATGRMSSPH SQSSLSIACE PHSASTTTLS SLGSDLGNGN 240
  241 GSTVPAFLMA APVTLPIGGQ MPTIKCLPGA SSAASTPKHS RYSKPRLSLS RVFNHSMPSV 300
  301 HGRPNLSLAP AGVPGSVNPP KRISTHQRNL SLDFRSMGIL LPPVSQVTNN HINHTQHHRN 360
  361 RSLDSALQRI PEVEVSSPNA ESENTFCSPS ILGATMCSKI ATTAATVTSA LSPPGTPTPA 420
  421 LMSTACTPTI GAVKGNVQHP VPKHEQSISL AAACRSSAVV ESCPTLRMRP KSSESVAANG 480
  481 QEMIGVIVSS TGNGSSSSNN SCSSAGSTKK REDLTSLGSD DSGIICGSES DQISLNRICH 540
  541 SHESLDSGEM DADADAEEEC VDLMDTTSID EEYNIMQPDH LCLYPPQAAS TELDCRTLRP 600
  601 SRKQKRQQQQ VLERKNLPSQ NQIESEDSVD AGVDARTRYR VMNMSQAAIN VELGTASNEI 660
  661 DPDVNYRESH QDPIADAPSL STPSVASTAS ATPSVTPTPI ATPTPTESTK NDQVLFKNFF 720
  721 GATKNAIFRT AQSIIENHEK KNAAKQKEQP DHSGTVSLVG SPNGGSSVPQ DLVKSPTDIS 780
  781 KKKEFFSLLT SSSSIKAAAA AAANSAASTP PATPTEALAA NSNSKLQPLS DPSADLKVKE 840
  841 RTLNLRLPGD SEGSEGALTK CSSINSIHKL KLPVPGVVKY FISEKAPVSD VLQKPEKGQS 900
  901 GLLRFFESPV FNIHFAVHYL FYSKEPGVLS FIGNKIFSFP DQEVDLYIPQ LVVMYIQMDE 960
  961 LAEVLDPYLT IRCRKSVDFS LKCLWLLEAY NYQVDSLGNS HNSSRKSKLA LMKEIFSKRE1020
 1021 HKQTQNDLKS AGTGGLHVGE PRSVVALAKK THHRSQSDAT VLLADFRSPH TLSISHRMYQ1080
 1081 QPPYTTQTLP TTPAKLCLGD LTSGHAFDNG CTCFETVRGQ VNGLLGQRTL CSCGAPKTSP1140
 1141 QKEFMKALMN VGKNLTSWPS KAEKTSALRM SLNLINKNLP ARVWLPLYSD IPHHVVRITE1200
 1201 EKTAVLNSKD KTPYIIYVEV VEIPDIYTSP LIPKMMPSLR HTKSEEHLDG SCLNSHQHLS1260
 1261 CSRTSSCSSS QQGTSCRRKK GADVDGGCGD AGPHNSCSNV HSLGGLQFQE DDVWSQEEDE1320
 1321 ITAQYLNMRK VSERDTISQI SLDSCDSRDQ GPPVVFNIGD VRLRHCSNLS CENTKSFSND1380
 1381 PEDPSAAALK EPWHEKEKLI RESSPYGHLS NWRLLSAIVK CGDDLRQELM ATQLLQMFKI1440
 1441 IWQEEQVDLW VRPYKIVCLS NDSGLIEPIL NTVSLHQIKK NSNKSLKEYF IDEYGSPSGE1500
 1501 SFRRAQKNFV QSCAAYCLIS YLLQVKDRHN GNILFHSDGH IIHIDFGFIL SISPKNLGFE1560
 1561 QSPFKLTPEF VEVMGGTSSE HWREFNKLLL VGMMSARKHM DRIINFVEIM RSNAHLPCFK1620
 1621 NGCSGTVQNL RKRFHMNLTE QEMERKVEQL VQDSLKSLST KLYDGYQYYT NGIL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: FBpp0305064, fwd...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: