Protein Overview: NitFhit-PA

General Information:
Name(s) found:	NitFhit-PA / FBpp0072385 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7291930\|gb\|AAF47347.1\| nitrilase and fragile histidine triad fusion protein [Drosophila melanogaster] [NCBI NR] gi\|52000768\|sp\|O76464.1\|NFT1_DROME RecName: Full=Nitrilase and fragile histidine triad fusion protein NitFhit; AltName: Full=NFT-1 protein; Includes: RecName: Full=Bis(5'-adenosyl)-triphosphatase; AltName: Full=Diadenosine 5',5'''-P1,P3-triphosphate hydro [NCBI NR] gi\|3228670\|gb\|AAC39137.1\| nitrilase and fragile histidine triad fusion protein NitFhit [Drosophila melanogaster] [NCBI NR] gi\|19527689\|gb\|AAL89959.1\| AT01846p [Drosophila melanogaster] [NCBI NR] gi\|17933642\|ref\|NP_525122.1\| nitrilase and fragile histidine triad fusion protein [Drosophila melanogaster] [NCBI NR] Nitrilase and fragile histidine triad fusion protein NitFhit OS=Drosophila melanogaster GN=NitFhit PE=1 SV=1 [Swiss-Prot] (O76464) Nitrilase and fragile histidine triad fusion protein NitFhit (NFT-1 protein) [Includes: Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (AP3A hydrolase) (AP [Swiss-Prot] The gene Nitrilase and fragile histidine triad fusion protein is referred to in FlyBase by the symbol Dmel\NitFhit (CG7067, FBgn0024945). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:203699..205311. It has the cytological map location 61B2. There is experimental evidence that it has the molecular function</span>: bis(5'-adenosyl)-triphosphatase activity. There is experimental evidence that it is involved in the biological process</span>: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG7067-PA translation from_gene[CG7067 NitFhit FBgn0024945] seq_release:3 mol_weight=52233 cds_boundaries:(3L:184,490..185,869[+]) aa_length:460 transcript_info:[CG7067-RA seq_release:3] gene_info:[gene symbol:NitFhit FBgn0024945 gene_boundaries:(3L:1 [hmr_yeast5_DM3-1_pombe.fasta] (O76464) NITFHIT protein (AT01846p) [DrosMelano7227.FASTAC.txt] (AE003467) NitFhit gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG7067-PA [Drosophila melanogaster]gi\|19527689\|gb\|AAL89959.1\| AT01846p [Drosophila melanogaster]gi\|17933642\|ref\|NP_525122.1\| CG7067-PA [Drosophila melanogaster]gi\|3228670\|gb\|AAC39137.1\| nitrilase and fragile histidine triad fusion protein NitFhit [Dros [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:203860..205242; ID=FBpp0072385; name=NitFhit-PA; parent=FBgn0024945,FBtr0072483; dbxref=FlyBase:FBpp0072385,FlyBase_Annotation_IDs:CG7067-PA,GB_protein:AAF47347.1,REFSEQ:NP_525122,GB_protein:AAF47347; MD5=c8ce0a6ca2e23a877b63ba129f7e5 [fly-100309-contam.fasta] AT01846p [Drosophila melanogaster] [nr-271106-contam.fasta] CG7067-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Nitrilase and fragile histidine triad fusion protein CG7067-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Nitrilase and fragile histidine triad fusion protein NitFhit (NFT-1 protein) [Includes: Bis(5'-adenosyl)-triphosphatase (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (AP3A hydrolase) (AP3Aase); Nitrilase homolog ] [nr-271106-contam.fasta] nitrilase and fragile histidine triad fusion protein NitFhit [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:203860..205242; ID=FBpp0072385; name=NitFhit-PA; parent=FBgn0024945,FBtr0072483; dbxref=FlyBase:FBpp0072385,FlyBase_Annotation_IDs:CG7067-PA,GB_protein:AAF47347.1,REFSEQ:NP_525122,GB_protein:AAF47347; MD5=c8ce0a6ca2e23a877b63ba129f7e581a; length=460; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:203860..205242; ID=FBpp0072385; name=NitFhit-PA; parent=FBgn0024945,FBtr0072483; dbxref=FlyBase:FBpp0072385,FlyBase_Annotation_IDs:CG7067-PA,GB_protein:AAF47347.1,REFSEQ:NP_525122,GB_protein:AAF47347; MD5=c8ce0a6ca2e23a877b63ba129f7e581a; length=460; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:203860..205242; ID=FBpp0072385; name=NitFhit-PA; parent=FBgn0024945,FBtr0072483; dbxref=FlyBase:FBpp0072385,FlyBase_Annotation_IDs:CG7067-PA,GB_protein:AAF47347.1,REFSEQ:NP_525122,GB_protein:AAF47347,FlyMine:FBpp0072385,modMine:FBpp0072385; MD5=c8ce0a6ca2e23a877b63ba129f7e581a; length=460; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:203860..205242; ID=FBpp0072385; name=NitFhit-PA; parent=FBgn0024945,FBtr0072483; dbxref=FlyBase:FBpp0072385,FlyBase_Annotation_IDs:CG7067-PA,GB_protein:AAF47347.1,REFSEQ:NP_525122,GB_protein:AAF47347,FlyMine:FBpp0072385,modMine:FBpp0072385; MD5=c8ce0a6ca2e23a877b63ba129f7e581a; length=460; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:203860..205242; ID=FBpp0072385; name=NitFhit-PA; parent=FBgn0024945,FBtr0072483; dbxref=FlyBase:FBpp0072385,FlyBase_Annotation_IDs:CG7067-PA,GB_protein:AAF47347.1,REFSEQ:NP_525122,GB_protein:AAF47347,FlyMine:FBpp0072385,modMine:FBpp0072385; MD5=c8ce0a6ca2e23a877b63ba129f7e581a; length=460; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0072385 type=protein; loc=3L:203860..205242; ID=FBpp0072385; name=NitFhit-PA; parent=FBgn0024945,FBtr0072483; dbxref=FlyBase:FBpp0072385,FlyBase_Annotation_IDs:CG7067-PA,GB_protein:AAF47347.1,REFSEQ:NP_525122,GB_protein:AAF47347,FlyMine:FBpp0072385,modMine:FBpp0072385; MD5=c8ce0a6ca2e23a877b63ba129f7e581a; length=460; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:203860..205242; ID=FBpp0072385; name=NitFhit-PA; parent=FBgn0024945,FBtr0072483; dbxref=FlyBase:FBpp0072385,FlyBase_Annotation_IDs:CG7067-PA,GB_protein:AAF47347.1,REFSEQ:NP_525122,GB_protein:AAF47347,UniProt/Swiss-Prot:O76464,FlyMine:FBpp0072385,modMine:FBpp0072385; MD5=c8ce0a6ca2e23a877b63ba129f7e581a; length=460; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	460 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [IDA]
Molecular Function:	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [TAS] bis(5'-adenosyl)-triphosphatase activity [IDA] nitrilase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLVNTTRR SIVIAIHQQL RRMSVQKRKD QSATIAVGQM RSTSDKAANL SQVIELVDRA  60
   61 KSQNACMLFL PECCDFVGES RTQTIELSEG LDGELMAQYR ELAKCNKIWI SLGGVHERND 120
  121 QKIFNAHVLL NEKGELAAVY RKLHMFDVTT KEVRLRESDT VTPGYCLERP VSTPVGQIGL 180
  181 QICYDLRFAE PAVLLRKLGA NLLTYPSAFT YATGKAHWEI LLRARAIETQ CFVVAAAQIG 240
  241 WHNQKRQSWG HSMIVSPWGN VLADCSEQEL DIGTAEVDLS VLQSLYQTMP CFEHRRNDIY 300
  301 ALTAYNLRSK EPTQDRPFAT NIVDKRTIFY ESEHCFAFTN LRCVVKGHVL VSTKRVTPRL 360
  361 CGLDCAEMAD MFTTVCLVQR LLEKIYQTTS ATVTVQDGAQ AGQTVPHVHF HIMPRRLGDF 420
  421 GHNDQIYVKL DERAEEKPPR TIEERIEEAQ IYRKFLTDIS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: NitFhit-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: