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Protein Overview: p130CAS-PB, p130...

General Information:
Name(s) found: p130CAS-PF / FBpp0289144 [FlyBase]
p130CAS-PB / FBpp0072377 [FlyBase]
Description(s) found:
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  • gi|7291919|gb|AAF47336.1| p130CAS, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|24654526|ref|NP_728478.1| p130CAS, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|221330706|ref|NP_001137861.1| p130CAS, isoform F [Drosophila melanogaster] [NCBI NR]
  • gi|220902400|gb|ACL83217.1| p130CAS, isoform F [Drosophila melanogaster] [NCBI NR]
  • gi|16182478|gb|AAL13502.1| GH02705p [Drosophila melanogaster] [NCBI NR]
  • The gene p130CAS is referred to in FlyBase by the symbol Dmel\p130CAS (CG1212, FBgn0035101). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:150857..174524. It has the cytological map location 61B1-61B2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: axonal defasciculation. 17 alleles are reported. The phenotypes of these alleles are annotated with: segmental nerve; intersegmental nerve; embryonic central nervous system. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • >CG1212-PB translation from_gene[CG1212 p130CAS FBgn0035101] seq_release:3 mol_weight=61673 cds_boundaries:(3L:152,832..154,535[+]) aa_length:568 transcript_info:[CG1212-RB seq_release:3] gene_info:[gene symbol:p130CAS FBgn0035101 gene_boundaries:(3L:1 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q95U71) GH02705p (CG1212) [DrosMelano7227.FASTAC.txt]
  • (AE003467) CG1212 gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG1212-PB, isoform B [Drosophila melanogaster]gi|16182478|gb|AAL13502.1| GH02705p [Drosophila melanogaster]gi|24654526|ref|NP_728478.1| CG1212-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:172202..173908; ID=FBpp0072377; name=p130CAS-PB; parent=FBgn0035101,FBtr0072475; dbxref=FlyBase:FBpp0072377,FlyBase_Annotation_IDs:CG1212-PB,GB_protein:AAF47336.1,REFSEQ:NP_728478,GB_protein:AAF47336; MD5=9f28b48666e5fe95682a222851c33 [fly-100309-contam.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0289144; name=p130CAS-PF; parent=FBgn0035101,FBtr0299866; dbxref=FlyBase:FBpp0289144,FlyBase_Annotation_IDs:CG1212-PF,REFSEQ:NP_001137861,GB_protein:ACL83217; MD5=9f28b48666e5fe95682a222851c335f5; length=568; re [fly-100309-contam.fasta]
  • GH02705p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG1212-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • p130CAS CG1212-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0072377; name=p130CAS-PB; parent=FBgn0035101,FBtr0072475; dbxref=FlyBase:FBpp0072377,FlyBase_Annotation_IDs:CG1212-PB,GB_protein:AAF47336.1,REFSEQ:NP_728478,GB_protein:AAF47336; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0289144; name=p130CAS-PF; parent=FBgn0035101,FBtr0299866; dbxref=FlyBase:FBpp0289144,FlyBase_Annotation_IDs:CG1212-PF,REFSEQ:NP_001137861,GB_protein:ACL83217; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0072377; name=p130CAS-PB; parent=FBgn0035101,FBtr0072475; dbxref=FlyBase:FBpp0072377,FlyBase_Annotation_IDs:CG1212-PB,GB_protein:AAF47336.1,REFSEQ:NP_728478,GB_protein:AAF47336; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0289144; name=p130CAS-PF; parent=FBgn0035101,FBtr0299866; dbxref=FlyBase:FBpp0289144,FlyBase_Annotation_IDs:CG1212-PF,REFSEQ:NP_001137861,GB_protein:ACL83217; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • GH02705p OS=Drosophila melanogaster GN=p130CAS PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0072377; name=p130CAS-PB; parent=FBgn0035101,FBtr0072475; dbxref=FlyBase:FBpp0072377,FlyBase_Annotation_IDs:CG1212-PB,GB_protein:AAF47336.1,REFSEQ:NP_728478,GB_protein:AAF47336,FlyMine:FBpp0072377,modMine:FBpp0072377; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0289144; name=p130CAS-PF; parent=FBgn0035101,FBtr0299866; dbxref=FlyBase:FBpp0289144,FlyBase_Annotation_IDs:CG1212-PF,REFSEQ:NP_001137861,GB_protein:ACL83217; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0072377; name=p130CAS-PB; parent=FBgn0035101,FBtr0072475; dbxref=FlyBase:FBpp0072377,FlyBase_Annotation_IDs:CG1212-PB,GB_protein:AAF47336.1,REFSEQ:NP_728478,GB_protein:AAF47336,FlyMine:FBpp0072377,modMine:FBpp0072377; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0289144; name=p130CAS-PF; parent=FBgn0035101,FBtr0299866; dbxref=FlyBase:FBpp0289144,FlyBase_Annotation_IDs:CG1212-PF,REFSEQ:NP_001137861,GB_protein:ACL83217; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0072377; name=p130CAS-PB; parent=FBgn0035101,FBtr0072475; dbxref=FlyBase:FBpp0072377,FlyBase_Annotation_IDs:CG1212-PB,GB_protein:AAF47336.1,REFSEQ:NP_728478,GB_protein:AAF47336,FlyMine:FBpp0072377,modMine:FBpp0072377; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0289144; name=p130CAS-PF; parent=FBgn0035101,FBtr0299866; dbxref=FlyBase:FBpp0289144,FlyBase_Annotation_IDs:CG1212-PF,REFSEQ:NP_001137861,GB_protein:ACL83217; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A4IJ58, GH02705p OS=Drosophila melanogaster GN=p130CAS PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0072377 type=protein; loc=3L:172202..173908; ID=FBpp0072377; name=p130CAS-PB; parent=FBgn0035101,FBtr0072475; dbxref=FlyBase:FBpp0072377,FlyBase_Annotation_IDs:CG1212-PB,GB_protein:AAF47336.1,REFSEQ:NP_728478,GB_protein:AAF47336,FlyMine:FBpp0072377,modMine:FBpp0072377; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0289144 type=protein; loc=3L:172202..173908; ID=FBpp0289144; name=p130CAS-PF; parent=FBgn0035101,FBtr0299866; dbxref=FlyBase:FBpp0289144,FlyBase_Annotation_IDs:CG1212-PF,REFSEQ:NP_001137861,GB_protein:ACL83217; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0072377; name=p130CAS-PB; parent=FBgn0035101,FBtr0072475; dbxref=FlyBase:FBpp0072377,FlyBase_Annotation_IDs:CG1212-PB,GB_protein:AAF47336.1,REFSEQ:NP_728478,GB_protein:AAF47336,UniProt/TrEMBL:Q95U71,FlyMine:FBpp0072377,modMine:FBpp0072377; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3L:172202..173908; ID=FBpp0289144; name=p130CAS-PF; parent=FBgn0035101,FBtr0299866; dbxref=FlyBase:FBpp0289144,FlyBase_Annotation_IDs:CG1212-PF,REFSEQ:NP_001137861,GB_protein:ACL83217,UniProt/TrEMBL:Q95U71; MD5=9f28b48666e5fe95682a222851c335f5; length=568; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 568 amino acids

    Gene Ontology:
    Cellular Component: focal adhesion [ISS]
    Biological Process: axonal defasciculation [IMP]
    cytoskeletal anchoring at plasma membrane [ISS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSSPRQNAS GSEFETYDIP KPATPVPLNY DSPRSGLPKA SNSTTTSSSS LGTRFETLKS  60
   61 VAASIAEESY DVPRPLILGS NQLQQQMSQM TPSSSASSLL TSDSLSLSFS SSNRSSLANM 120
  121 PDYDIPRRNP LPVRRQQSGL TYDFPLPPLQ EQVPRVLCTP STVTTTKELP LELSSALETL 180
  181 AKLQLQTTAA INRLLSFVVP NWRTRAQLEP AIMDLKLAAL RLRTTLHDLA EFGEGALGNA 240
  241 TRSEDRNLAL KLRPLVRALR DANKLIHDSS ESLDAQGAWS IDQLARSDEK HGCRPPDALD 300
  301 QLMVCAQTLT EDVRSTTSFI QGNASLLFKR QLTVGHNGGS GTGVLEGSRG SAEWLEDYDY 360
  361 VAFESKDAAA RKNEALREAI PADLKTQFDT VIRTAESSAM GAGSGSIPTT PTARTTPTTP 420
  421 CKSPEMTDKD KKLVRYYAQQ ISTHMGNLMQ AIDSFLETVE KNQPPKFFIA YGKFVVVSAH 480
  481 NLVTIGDNVY RNISKEALRE KILRCTNALS DALKTCVLKS KKAAAHFPSG SAVQEMVDSV 540
  541 VHINNLARDL KSVMLQAVHL STAAGVGA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle