Protein Overview: p130CAS-PG

General Information:
Name(s) found:	p130CAS-PG / FBpp0291103 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24654522\|ref\|NP_612002.2\| p130CAS, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23092660\|gb\|AAF47335.2\| p130CAS, isoform A [Drosophila melanogaster] [NCBI NR] gi\|148616248\|gb\|ABQ96885.1\| Crk-associated substrate [Drosophila melanogaster] [NCBI NR] The gene p130CAS is referred to in FlyBase by the symbol Dmel\p130CAS (CG1212, FBgn0035101). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:150857..174524. It has the cytological map location 61B1-61B2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: axonal defasciculation. 17 alleles are reported. The phenotypes of these alleles are annotated with: segmental nerve; intersegmental nerve; embryonic central nervous system. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] >CG1212-PA translation from_gene[CG1212 p130CAS FBgn0035101] seq_release:3 mol_weight=85623 cds_boundaries:(3L:141,882..154,535[+]) aa_length:793 transcript_info:[CG1212-RA seq_release:3] gene_info:[gene symbol:p130CAS FBgn0035101 gene_boundaries:(3L:1 [hmr_yeast5_DM3-1_pombe.fasta] (AAF47335) CG1212-PA [DrosMelano7227.FASTAC.txt] CG1212-PA, isoform A [Drosophila melanogaster]gi\|24654522\|ref\|NP_612002.2\| CG1212-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(161252..161371,167476..167619,168581..168850,172061..173908); ID=FBpp0072376; name=p130CAS-PA; parent=FBgn0035101,FBtr0072474; dbxref=FlyBase:FBpp0072376,FlyBase_Annotation_IDs:CG1212-PA,GB_protein:AAF47335.2,REFSEQ:NP_612002,GB_ [fly-100309-contam.fasta] p130CAS CG1212-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG1212-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(161252..161371,167476..167619,168581..168850,172061..173908); ID=FBpp0072376; name=p130CAS-PA; parent=FBgn0035101,FBtr0072474; dbxref=FlyBase:FBpp0072376,FlyBase_Annotation_IDs:CG1212-PA,GB_protein:AAF47335.2,REFSEQ:NP_612002,GB_protein:AAF47335; MD5=1245ef7035f2756231d97d6447cc3643; length=793; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(161252..161371,167476..167619,168581..168850,172061..173908); ID=FBpp0072376; name=p130CAS-PA; parent=FBgn0035101,FBtr0072474; dbxref=FlyBase:FBpp0072376,FlyBase_Annotation_IDs:CG1212-PA,GB_protein:AAF47335.2,REFSEQ:NP_612002,GB_protein:AAF47335; MD5=1245ef7035f2756231d97d6447cc3643; length=793; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:join(161252..161371,167476..167619,168581..168850,172061..173908); ID=FBpp0291103; name=p130CAS-PG; parent=FBgn0035101,FBtr0301889; dbxref=FlyBase:FBpp0291103,FlyBase_Annotation_IDs:CG1212-PG; MD5=1245ef7035f2756231d97d6447cc3643; length=793; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Crk-associated substrate OS=Drosophila melanogaster GN=p130CAS PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(161252..161371,167476..167619,168581..168850,172061..173908); ID=FBpp0291103; name=p130CAS-PG; parent=FBgn0035101,FBtr0301889; dbxref=FlyBase:FBpp0291103,REFSEQ:NP_001163302,GB_protein:ACZ94574,FlyBase_Annotation_IDs:CG1212-PG; MD5=1245ef7035f2756231d97d6447cc3643; length=793; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] Crk-associated substrate OS=Drosophila melanogaster GN=p130CAS PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3L:join(161252..161371,167476..167619,168581..168850,172061..173908); ID=FBpp0291103; name=p130CAS-PG; parent=FBgn0035101,FBtr0301889; dbxref=FlyBase:FBpp0291103,REFSEQ:NP_001163302,GB_protein:ACZ94574,FlyBase_Annotation_IDs:CG1212-PG; MD5=1245ef7035f2756231d97d6447cc3643; length=793; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(161252..161371,167476..167619,168581..168850,172061..173908); ID=FBpp0291103; name=p130CAS-PG; parent=FBgn0035101,FBtr0301889; dbxref=FlyBase:FBpp0291103,REFSEQ:NP_001163302,GB_protein:ACZ94574,FlyBase_Annotation_IDs:CG1212-PG; MD5=1245ef7035f2756231d97d6447cc3643; length=793; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of A4IJ58, Crk-associated substrate OS=Drosophila melanogaster GN=p130CAS PE=2 SV=1 [DROME.fasta.20160308] FBpp0291103 type=protein; loc=3L:join(161252..161371,167476..167619,168581..168850,172061..173908); ID=FBpp0291103; name=p130CAS-PG; parent=FBgn0035101,FBtr0301889; dbxref=FlyBase:FBpp0291103,REFSEQ:NP_001163302,GB_protein:ACZ94574,FlyBase_Annotation_IDs:CG1212-PG; MD5=1245ef7035f2756231d97d6447cc3643; length=793; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(161252..161371,167476..167619,168581..168850,172061..173908); ID=FBpp0291103; name=p130CAS-PG; parent=FBgn0035101,FBtr0301889; dbxref=FlyBase:FBpp0291103,REFSEQ:NP_001163302,GB_protein:ACZ94574,FlyBase_Annotation_IDs:CG1212-PG,UniProt/TrEMBL:Q7KVE5; MD5=1245ef7035f2756231d97d6447cc3643; length=793; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	793 amino acids
Gene Ontology:
Cellular Component:	focal adhesion [ISS]
Biological Process:	axonal defasciculation [IMP] cytoskeletal anchoring at plasma membrane [ISS]
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDKTTSSSV SVSTSCCSSN AINADLDYDV PVSRRILIKS KLYAKAIYDN YADTSDELPF  60
   61 KKGDILTVLE QDTEGFQGWW LCSLRNRQGL CPGNRLRVLN SYDSGCFSPS PASSPVPSLA 120
  121 ASTATLDSSI CSAEIYENGS VISAVSSSNS NSGGASSGLG SESVSRVSRR SWHASPTKVI 180
  181 TPQRHGDVYI YNYSPGSATG SGARAAPSTP QQQIYSNQSI YQNFAMMSSP RQNASGSEFE 240
  241 TYDIPKPATP VPLNYDSPRS GLPKASNSTT TSSSSLGTRF ETLKSVAASI AEESYDVPRP 300
  301 LILGSNQLQQ QMSQMTPSSS ASSLLTSDSL SLSFSSSNRS SLANMPDYDI PRRNPLPVRR 360
  361 QQSGLTYDFP LPPLQEQVPR VLCTPSTVTT TKELPLELSS ALETLAKLQL QTTAAINRLL 420
  421 SFVVPNWRTR AQLEPAIMDL KLAALRLRTT LHDLAEFGEG ALGNATRSED RNLALKLRPL 480
  481 VRALRDANKL IHDSSESLDA QGAWSIDQLA RSDEKHGCRP PDALDQLMVC AQTLTEDVRS 540
  541 TTSFIQGNAS LLFKRQLTVG HNGGSGTGVL EGSRGSAEWL EDYDYVAFES KDAAARKNEA 600
  601 LREAIPADLK TQFDTVIRTA ESSAMGAGSG SIPTTPTART TPTTPCKSPE MTDKDKKLVR 660
  661 YYAQQISTHM GNLMQAIDSF LETVEKNQPP KFFIAYGKFV VVSAHNLVTI GDNVYRNISK 720
  721 EALREKILRC TNALSDALKT CVLKSKKAAA HFPSGSAVQE MVDSVVHINN LARDLKSVML 780
  781 QAVHLSTAAG VGA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: p130CAS-PG

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: