YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: tsr-PA

General Information:
Name(s) found: tsr-PA / FBpp0072097 [FlyBase]
Description(s) found:
Found 29 descriptions.
SHOW ALL
  • The gene twinstar is referred to in FlyBase by the symbol Dmel\tsr (CG4254, FBgn0011726). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19931971..19934359. It has the cytological map location 60B5. There is experimental evidence that it has the molecular function</span>: actin binding; SUMO binding. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: anatomical structure development; establishment of planar polarity; organ development; sensory organ development; actin filament-based process; organ morphogenesis; cell division; regulation of cellular component organization; reproductive process in a multicellular organism; protein complex biogenesis. 43 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; cytoplasmic part; cell cycle; adult segment; male germline cyst; M phase of meiotic cell cycle; spermatocyte; actomyosin contractile ring; meiosis II; wing hair; cell projection; imaginal precursor; adult cuticle; external compound sense organ. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 148 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: leg segmentation [IMP]
    regulation of lamellipodium assembly [IMP]
    cytokinesis, actomyosin contractile ring assembly [TAS]
    mushroom body development [IMP]
    actin filament depolymerization [NAS]
    actin filament polymerization [IMP]
    actin filament organization [IMP]
    cytokinesis [IMP]
    establishment of ommatidial planar polarity [IMP]
    border follicle cell migration [IMP]
    female gonad development [IMP]
    compound eye development [IGI]
    axonogenesis [IMP]
    establishment of planar polarity [IMP]
    establishment of imaginal disc-derived wing hair orientation [IMP]
    Molecular Function: SUMO binding [IPI]
    actin binding [IMP][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASGVTVSDV CKTTYEEIKK DKKHRYVIFY IRDEKQIDVE TVADRNAEYD QFLEDIQKCG  60
   61 PGECRYGLFD FEYMHQCQGT SESSKKQKLF LMSWCPDTAK VKKKMLYSSS FDALKKSLVG 120
  121 VQKYIQATDL SEASREAVEE KLRATDRQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] PSI-BLAST 41.69897 Cofilin (actin depolymerizing factor, ADF)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  7.52071741004022 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  6.04859625643932 bayes_pls_golite062009
  • actin filament binding
    		•  5.45532510538573 bayes_pls_golite062009
  • protein binding
    		•  2.93027234013365 bayes_pls_golite062009
  • binding
    		•  2.84811181543046 bayes_pls_golite062009
  • protein kinase activity
    		•  2.04816578082974 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.67227267699496 bayes_pls_golite062009
  • kinase activity
    		•  1.55883505515498 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.47782133980448 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate binding
    		•  1.3406661967545 bayes_pls_golite062009
  • transferase activity
    		•  0.591259446255369 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.535442033390394 bayes_pls_golite062009
  • signal transducer activity
    		•  0.535442033390394 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.482954032096802 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  0.445404590790816 bayes_pls_golite062009
  • structural molecule activity
    		•  0.391701411061931 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.270847057375333 bayes_pls_golite062009
  • actin monomer binding
    		•  0.224304003054399 bayes_pls_golite062009
  • receptor binding
    		•  0.0743355952407823 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle