YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: eIF6-PA

General Information:
Name(s) found: eIF6-PA / FBpp0072144 [FlyBase]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • The gene eIF6 is referred to in FlyBase by the symbol Dmel\eIF6 (CG17611, FBgn0034915). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19736769..19737822. It has the cytological map location 60A3. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translational initiation. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 245 amino acids

    Gene Ontology:
    Cellular Component: cytosol [ISS][NAS]
    Biological Process: mature ribosome assembly [IEA]
    translational initiation [ISS]
    translation [NAS]
    Molecular Function: translation initiation factor activity [ISS]
    ribosome binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRVQFENN DDIGVFTKLT NTYCLVAIGG SETFYSAFEA ELGDTIPVVH ANVGGCRIIG  60
   61 RLTVGNRNGL LVPNSTTDEE LQHLRNSLPD AVKIYRVEER LSALGNVIAC NDYVALVHPD 120
  121 LDKETEEIIA DVLKVEVFRQ TIADNSLVGS YAVLSNQGGM VHPKTSIQDQ DELSSLLQVP 180
  181 LVAGTVNRGS EVLAAGMVVN DWLSFVGMNT TATEISVIES VFKLNQAQPA TVTTKLRAAL 240
  241 IEDMS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..245] PSI-BLAST 104.0 Ribosome anti-association factor eIF6 (aIF6)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  2.82313826209658 bayes_pls_golite062009
  • ribosomal large subunit binding
    		•  2.29551693750603 bayes_pls_golite062009
  • binding
    		•  1.48640777619976 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.14138534491569 bayes_pls_golite062009
  • hydrolase activity
    		•  1.05437300113124 bayes_pls_golite062009
  • catalytic activity
    		•  0.889920589881492 bayes_pls_golite062009
  • protein binding
    		•  0.21271994410782 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle