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Protein Overview: CG18128-PA

General Information:
Name(s) found: CG18128-PA / FBpp0072003 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG18128 (CG18128, FBgn0034898). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19606320..19607459. It has the cytological map location 59F6. Based on sequence similarity, it is predicted to have molecular function</span>: purine-nucleoside phosphorylase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: nucleoside metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 339 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nucleoside metabolic process [IEA]
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [IEA]
    Molecular Function: purine-nucleoside phosphorylase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCNYDCCKSR SPIAKRMAAR KLLQMEEEER RKPKLVIPTP QSLFYPFEEV EAMAKYIVNV  60
   61 SHIRPKYGLI CGSFLSDMVS LVEQPVVIPY EDIPNFPDGI EPDCSFVLGT VMGAPIIALV 120
  121 HSFHSCDGYN LATCALPVRV MQLCGVRTIM LTSEAAAVDH GFALGDIMLV QDHINVVGMM 180
  181 HQTPLEGPSD PRFGSRRFSM VNAYDKDLLE KALEIGKRMG IQKFLHSGVL ACMGGPILGT 240
  241 VAEERMLRTM EVSAVGMSLV PEVIAAHHGG LKVLAFVVIS RAASDKESEE SDKDKEKDTD 300
  301 RDSKQDKREQ DSQEPVPLPR LQACSDLIGR LMYCMHLEI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..339] PSI-BLAST 81.154902 Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.18268586151113 bayes_pls_golite062009
  • transferase activity
    		•  0.716715652241981 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  0.643658103569746 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  0.628296979382929 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle