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Protein Overview: Nup214-PA

General Information:
Name(s) found: Nup214-PA / FBpp0071905 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Nup214 is referred to in FlyBase by the symbol Dmel\Nup214 (CG3820, FBgn0010660). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18806459..18812255. It has the cytological map location 59B4-59B6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: protein import into nucleus, docking. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1711 amino acids

    Gene Ontology:
    Cellular Component: nuclear pore [IMP][NAS]
    Biological Process: protein import into nucleus, docking [IDA]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQNAPDCED TQDFQFKLHH KIVAFKKCGE PRSNVNLLAV SSSRGLLFAG SPTQPELKVI  60
   61 IVKDLVNAKS TAQQPQARLV PLPSIPNYIA CSSDGNLLAV NHTQNGTSLL SIYAVLSFMT 120
  121 PDVRPVYNIR LAAEDHVHGV QLLWNPVLPN SLAVVLSNGA LAMYALKEGG NFEMHSLDKN 180
  181 QQVKCGCWSP KGKQIVLGFP GGTVKQFKPD LTLAKTLLCP PNIHDAPFDT IAIQWLSTFQ 240
  241 FAVIFLQHGE DCSPSLYILN APKAGAPSYI NYYDICYSMN GPRNHQFVFS HVPQWNLLLV 300
  301 VSANGVEVGI MRSTEAGDTP AWQQLTLLDE ARIEMPLSED KDETFPLGFA FDTSTTHQLT 360
  361 INEKKLQTMP MVHVLSSDGE LLSFNFLNVL PTAVSVCSPP PPVADTSGQF KPLNMLLASE 420
  421 EEEQPAWAAS PSKAPAATPA ASSDISFAFT PNTVTSTPAP SKDKQPSLFS GFGAAAAKAP 480
  481 APQLSFGTAP TSSPVSFGAP TTNAAKPTTP FGGFGTQATT TAMGSMFSAS GANAFGGMAL 540
  541 NKPAIASVTP RTAAPGSTVP ATPASAPANK PLYTVPLTFT PVDTKPATSA PPQIADESLK 600
  601 PDDTEPIIKD MIALQIEAFS KDIQKQKEQT KELLKGIAAP SALRAYAKRL DDLQELNEQA 660
  661 KDVEFELDVQ GLRQGLNEAY AIVAECRGKL EIYRKPEITR LMNSSSCDPS GRRMLARLQS 720
  721 YVAANEAQLR LAQQHVDLQW EQFQDVVRRN SKSRMHMPCL EGIYQRLTRL QNLTSNQRIV 780
  781 QNNIKSKLKE RGLLQAALLD QEKSRTRTNE AVDTLTDSIL TMSLSQVVDS NAAKLTRERL 840
  841 QKIRNIVQLQ KINVICPQRP DRVGLKSEVI LETKRRAEQI KRAAAKPATA NKYTQAAVAP 900
  901 PSPPDVAPTP AVAPMPQATV TVAPPLPKPM PSIPSVVEKP GVPTHPTTPV ATPFSFSQSI 960
  961 PFVKTSTVTP TTNTVTPGEA AKPGLSIFGG STISSFSFGG GAAKSALSFG TGSPAVAAPT1020
 1021 PKPNPLSAVE KPTPEPTKPK EQKAAESKEF KAVQPETEES KVPQKPKAET ENKSFGFGGF1080
 1081 TGTGGTVGNT SSSPFSFGGL GSSLGFGGTA AAVPKSEPSS TATTSVATSA STAPFGIFSA1140
 1141 ALAKPSNSEP ITTVTSNTTT ITSKPTNVIA SSSVTDAPSV TTTNAVTSST DPIGGLFSSV1200
 1201 TICKPNTPAD TTKPANIFGG GLSAGSFSFG GTIDASKGLF GSTKPVATAP TSVTEANNKT1260
 1261 DPISTTPSAI STTTATTTVS SPAVVPAAVT AAVPATSSTT VTSSTAVPGS AFSFSNAFST1320
 1321 LSAGGAAAPT TSASAPLAAK SPTATSTGNN SSNSVFGGGF AVATSTAAPV ASPFQSAAKS1380
 1381 PVSSANIFGS IPKAETSVFG GATTAPSNTT AAATPDAPPA GLFASAAISN PSPFGSPTTR1440
 1441 APASGGNIFG QAVKPSVFGQ PAQAGDSGGS IFGGGSASTP FGSSSIFGGG NTQGAVGAPA1500
 1501 AGSTSIFGQK VFGQSSAAAP AAGGNIFSNP VGSPQASPFG GGGNSIFGSP ATAPPASGGS1560
 1561 IFGGGSSSGG FGSFTQTTPA QGGFGGGFGQ GGGGSVAQTG FGSPQAPQQQ TTTPGGFGAK1620
 1621 PVFGGSPAFG ASPTFGGGAT FGSPKGFGGF GGASPVASPP PFGAAAKPAQ GNIFETLGGQ1680
 1681 ESGLSFGNLA QTGNSNAQKP AFGGSSFMNY R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..424] PSI-BLAST 142.0 No description for 2oitA was found.
    2 View Details [425..518] deduced N/A No confident structure predictions are available.
    3 View Details [519..628] MSA 2.140988 View MSA. No confident structure predictions are available.
    4 View Details [629..861] deduced N/A No confident structure predictions are available.
    5 View Details [862..953] deduced N/A No confident structure predictions are available.
    6 View Details [954..1032] deduced N/A No confident structure predictions are available.
    7 View Details [1033..1226] deduced N/A No confident structure predictions are available.
    8 View Details [1227..1390] deduced N/A No confident structure predictions are available.
    9 View Details [1391..1457] deduced N/A No confident structure predictions are available.
    10 View Details [1458..1711] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.63

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
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