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Protein Overview: CG3290-PA

General Information:
Name(s) found: CG3290-PA / FBpp0071695 [FlyBase]
Description(s) found:
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  • gi|7291392|gb|AAF46820.1| CG3290 [Drosophila melanogaster] [NCBI NR]
  • gi|24657835|ref|NP_611654.1| CG3290 [Drosophila melanogaster] [NCBI NR]
  • gi|21430020|gb|AAM50688.1| GH28372p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG3290 (CG3290, FBgn0034711). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18093510..18095492. It has the cytological map location 58D1. Based on sequence similarity, it is predicted to have molecular function</span>: alkaline phosphatase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG3290-PA translation from_gene[CG3290 CG3290 FBgn0034711] seq_release:3 mol_weight=58228 cds_boundaries:(2R:17,249,686..17,251,520[-]) aa_length:538 transcript_info:[CG3290-RA seq_release:3] gene_info:[gene symbol:CG3290 FBgn0034711 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W274) CG3290 protein (GH28372p) [DrosMelano7227.FASTAC.txt]
  • (AE003456) CG3290 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG3290-PA [Drosophila melanogaster]gi|21430020|gb|AAM50688.1| GH28372p [Drosophila melanogaster]gi|24657835|ref|NP_611654.1| CG3290-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(18093637..18094154,18094224..18094914,18095067..18095474); ID=FBpp0071695; name=CG3290-PA; parent=FBgn0034711,FBtr0071782; dbxref=FlyBase:FBpp0071695,FlyBase_Annotation_IDs:CG3290-PA,GB_protein:AAF46820.1,REFSEQ:NP_611654,G [fly-100309-contam.fasta]
  • CG3290-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH28372p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(18093637..18094154,18094224..18094914,18095067..18095474); ID=FBpp0071695; name=CG3290-PA; parent=FBgn0034711,FBtr0071782; dbxref=FlyBase:FBpp0071695,FlyBase_Annotation_IDs:CG3290-PA,GB_protein:AAF46820.1,REFSEQ:NP_611654,GB_protein:AAF46820; MD5=980dd9ba47a4511fc3e0b54d9d197c59; length=538; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(18093637..18094154,18094224..18094914,18095067..18095474); ID=FBpp0071695; name=CG3290-PA; parent=FBgn0034711,FBtr0071782; dbxref=FlyBase:FBpp0071695,FlyBase_Annotation_IDs:CG3290-PA,GB_protein:AAF46820.1,REFSEQ:NP_611654,GB_protein:AAF46820; MD5=980dd9ba47a4511fc3e0b54d9d197c59; length=538; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Alkaline phosphatase OS=Drosophila melanogaster GN=CG3290 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(18093637..18094154,18094224..18094914,18095067..18095474); ID=FBpp0071695; name=CG3290-PA; parent=FBgn0034711,FBtr0071782; dbxref=FlyBase:FBpp0071695,FlyBase_Annotation_IDs:CG3290-PA,GB_protein:AAF46820.1,REFSEQ:NP_611654,GB_protein:AAF46820,FlyMine:FBpp0071695,modMine:FBpp0071695; MD5=980dd9ba47a4511fc3e0b54d9d197c59; length=538; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(22207562..22207969,22206719..22207409,22206132..22206649)); ID=FBpp0071695; name=CG3290-PA; parent=FBgn0034711,FBtr0071782; dbxref=FlyBase:FBpp0071695,FlyBase_Annotation_IDs:CG3290-PA,GB_protein:AAF46820.1,REFSEQ:NP_611654,GB_protein:AAF46820,FlyMine:FBpp0071695,modMine:FBpp0071695; MD5=980dd9ba47a4511fc3e0b54d9d197c59; length=538; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(22207562..22207969,22206719..22207409,22206132..22206649)); ID=FBpp0071695; name=Alp2-PA; parent=FBgn0283480,FBtr0071782; dbxref=FlyBase:FBpp0071695,FlyBase_Annotation_IDs:CG3290-PA,GB_protein:AAF46820.1,REFSEQ:NP_611654,GB_protein:AAF46820,FlyMine:FBpp0071695,modMine:FBpp0071695; MD5=980dd9ba47a4511fc3e0b54d9d197c59; length=538; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Alkaline phosphatase OS=Drosophila melanogaster GN=Alp2 PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0071695 type=protein; loc=2R:complement(join(22207562..22207969,22206719..22207409,22206132..22206649)); ID=FBpp0071695; name=Alp2-PA; parent=FBgn0283480,FBtr0071782; dbxref=FlyBase:FBpp0071695,FlyBase_Annotation_IDs:CG3290-PA,GB_protein:AAF46820.1,REFSEQ:NP_611654,GB_protein:AAF46820,FlyMine:FBpp0071695,modMine:FBpp0071695; MD5=980dd9ba47a4511fc3e0b54d9d197c59; length=538; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(22207562..22207969,22206719..22207409,22206132..22206649)); ID=FBpp0071695; name=Alp2-PA; parent=FBgn0283480,FBtr0071782; dbxref=FlyBase:FBpp0071695,FlyBase_Annotation_IDs:CG3290-PA,GB_protein:AAF46820.1,REFSEQ:NP_611654,GB_protein:AAF46820,UniProt/TrEMBL:Q9W274,FlyMine:FBpp0071695,modMine:FBpp0071695; MD5=980dd9ba47a4511fc3e0b54d9d197c59; length=538; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 538 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEA]
    Molecular Function: alkaline phosphatase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHISQRRCLY PIFLFLLAFV GTALGRVQEV HNVLELTGQK ASKLRFSTDV ATGKYTPPEE  60
   61 MDPQFWYKLA DEEIAKRLQL PQPNSDRAKN VIMFLGDGMP ISTVTAARIL KGQRQGNTGE 120
  121 ESSLSFEKFP YSGLSRTYCA NAQVPDSACT ATAYLCGVKT NIINIGVSAA VNFNNCTASQ 180
  181 DPANRLTSIA EWAQNAGKST GFVTTTTLTH ASPSGAYAKT ANRMWQSDTD VTSYGVDAST 240
  241 CVDMATQLVT QTPGKNFEVM FGGGMGKFLP KTTKDSHGKY GERSDGVNLL SRWQGLHDKG 300
  301 VLVTNRKQLL NLDVSAASSI IGTFQSGLMD FHMDADPTYQ PTLSELTEVA IKKLSHNENG 360
  361 YFVFIEGGLI DYGNHYTQAG YALDEALEFE KAIQLAREMT NISDTLIVVT ADHGHAVSIA 420
  421 GYPGRGTPIL GLNQHDTDIN GVKYSVLNYA AGPNQYLDEH GQRIPLDDIL GPDDAISPSY 480
  481 IDKEIGVHSG EDVGIWASGP QSHLFTGVMQ QSTIPHLMAY ASCVGSGKQV CGSSGRKT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..538] PSI-BLAST 144.0 X-ray structure of alkaline phosphatase from human placenta in complex with 5'-AMP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, acting on ester bonds
    		•  2.8318172470006 bayes_pls_golite062009
  • hydrolase activity
    		•  2.68329882022147 bayes_pls_golite062009
  • catalytic activity
    		•  2.31328968099128 bayes_pls_golite062009
  • phosphatase activity
    		•  1.51067400873904 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  1.32325931665891 bayes_pls_golite062009
  • alkaline phosphatase activity
    		•  0.688134376880261 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.515209766971615 bayes_pls_golite062009
  • kinase activity
    		•  0.503509300116176 bayes_pls_golite062009
  • binding
    		•  0.48922825585019 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.356909797780746 bayes_pls_golite062009
  • protein binding
    		•  0.208332656410563 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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