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Protein Overview: Cht12-PA

General Information:
Name(s) found: Cht12-PA / FBpp0071473 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene Cht12 is referred to in FlyBase by the symbol Dmel\Cht12 (CG30293, FBgn0050293). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16950683..16952468. It has the cytological map location 57B16. Based on sequence similarity, it is predicted to have molecular function</span>: chitin binding; chitinase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: chitin metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 470 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEA]
    Biological Process: chitin catabolic process [IEA]
    chitin metabolic process [ISS]
    Molecular Function: chitinase activity [ISS]
    chitin binding [ISS]
    cation binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSFQYVFMI MIFLICGCIA KEYNVFCQYD LGSYYYKGRS QFFEWHLDSR LCTHLVLGSG  60
   61 IGVDGDSGEL RITDKILLLE KDKLSSVKTM KWDSIKKVMF TIGGWEEDSS SFSRMVASPK 120
  121 KRDNFYSSML EFMFRWGFDG VQIDWRYPTL LGGHPDDRQN FVILLEELGL IFRKNQLILM 180
  181 VAVLGRRDNR ILESYNIPEI VNHSDFIHLM MHDEQDPYHL RLAYNAPLVG YEGSVTDSIM 240
  241 HWKRNGGAPE KLILGIPLFV RSFTMDRNQS TVGSACKGPG RQTKQSHRPG FMTYNEWCVQ 300
  301 QSKWSRMFDQ LAKVPYATRG DQWVSYENPR SIWAKMHLLQ EHKLGGAMAW TIDVDDFRGR 360
  361 CGEQHGLLRV IFSALGDKNG LTTEKPTTEA SGLCPHDGFS RDGWDCRLYH ECRDGERIYY 420
  421 ECLEGQYFDE NQIVCRPAAE VKCDQNFVIW RPGMPVYSYD NMPLNLKIVE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..470] PSI-BLAST 88.69897 Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against human chitinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • chitinase activity
    		•  6.40555694403866 bayes_pls_golite062009
  • imaginal disc growth factor activity
    		•  3.9608908661313 bayes_pls_golite062009
  • growth factor activity
    		•  2.18932950777991 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  1.91170236789651 bayes_pls_golite062009
  • receptor binding
    		•  1.89435893935497 bayes_pls_golite062009
  • amylase activity
    		•  1.38959979746158 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  1.34796838721403 bayes_pls_golite062009
  • chitin binding
    		•  1.29046765706168 bayes_pls_golite062009
  • binding
    		•  1.1885466730171 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.80333288291596 bayes_pls_golite062009
  • glucosidase activity
    		•  0.766503513427695 bayes_pls_golite062009
  • protein binding
    		•  0.690517649847952 bayes_pls_golite062009
  • catalytic activity
    		•  0.534516847146079 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • hexosaminidase activity
    		•  0.21148675734804 bayes_pls_golite062009
  • hydrolase activity
    		•  0.178746202646272 bayes_pls_golite062009
  • pattern binding
    		•  0.113396113487931 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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