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Protein Overview: Mgat1-PA

General Information:
Name(s) found: Mgat1-PA / FBpp0085571 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene UDP-GlcNAc:a-3-D-mannoside-Ã?&#142;Ã?²-1,2-N-acetylglucosaminyltransferase I is referred to in FlyBase by the symbol Dmel\Mgat1 (CG13431, FBgn0034521). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16446661..16449832. It has the cytological map location 57A5. There is experimental evidence that it has the molecular function</span>: acetylglucosaminyltransferase activity; alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; protein amino acid N-linked glycosylation via asparagine; adult locomotory behavior; mushroom body development. 5 alleles are reported. The phenotype of these alleles is annotated with: mushroom body beta-lobe. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 458 amino acids

    Gene Ontology:
    Cellular Component: Golgi membrane [IEA]
    Biological Process: mushroom body development [IMP]
    determination of adult lifespan [IMP]
    protein amino acid N-linked glycosylation via asparagine [IDA]
    adult locomotory behavior [IMP]
    Molecular Function: acetylglucosaminyltransferase activity [IDA]
    alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTRKVLLVI GFLVTWTYAT YYLLLRQTGI HTSRHQSLQA YKLNSQARDA NMQSHHLAKN  60
   61 VFEFVKLKYL EKQPPSVAST PQISIIAAEI SAELPEQHVA KSATARIPTK TYLANGEPVF 120
  121 PVVVFACNRV SVKKCIDNLV QYRPSVEQFP IIVSQDCGDE PTKEAILSYG KQVTLIEQPD 180
  181 LSDITVLPKE KKFKGYYKIA RHYGWALNTT FAVGFEFVII VEDDLNVAPD FFEYFLGTHK 240
  241 LLKQDPSLWC VSAWNDNGKA AVVDAAQPEL LYRTDFFPGL GWMLTKDLWA ELSVKWPKSF 300
  301 WDDWIRHPAQ RKDRVCIRPE ISRTRTFGKI GVSNGLFFDK YLKHIKLSED FVQFTKINMS 360
  361 YLLKDNYDNT FLRRVYTYPI VTYDELRRNL IRIEGPVRIQ YTTREQYKRT TKMLGLMDDF 420
  421 KSGVPRTAYH GIVSFYYNKR RVHLAPNANW KGYELSWS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] MSA 3.066982 View MSA. No confident structure predictions are available.
    2 View Details [117..458] PSI-BLAST 109.0 N-acetylglucosaminyltransferase I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transferase activity
    		•  2.82233986182523 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  2.58861838579068 bayes_pls_golite062009
  • catalytic activity
    		•  2.25720704697246 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  2.04393180556087 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.77645651562292 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  1.51711005399931 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  1.21894113759929 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.67147527259372 bayes_pls_golite062009
  • uridylyltransferase activity
    		•  0.54930147038803 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  0.48277064848483 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  0.464576210651411 bayes_pls_golite062009
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  0.10541627748542 bayes_pls_golite062009
  • UDP-N-acetylglucosamine diphosphorylase activity
    		•  0.0524448119433805 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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