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Protein Overview: CG11048-PA

General Information:
Name(s) found: CG11048-PA / FBpp0085625 [FlyBase]
Description(s) found:
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  • gi|21626920|gb|AAF57502.2| CG11048 [Drosophila melanogaster] [NCBI NR]
  • gi|19922624|ref|NP_611459.1| CG11048 [Drosophila melanogaster] [NCBI NR]
  • gi|16768214|gb|AAL28326.1| GH24459p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG11048 (CG11048, FBgn0034487). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16127492..16130387. It has the cytological map location 56F11. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cilium assembly. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG11048-PA translation from_gene[CG11048 CG11048 FBgn0034487] seq_release:3 mol_weight=88103 cds_boundaries:(2R:15,303,819..15,306,479[+]) aa_length:765 transcript_info:[CG11048-RA seq_release:3] gene_info:[gene symbol:CG11048 FBgn0034487 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V902) CG11048 protein (GH24459p) [DrosMelano7227.FASTAC.txt]
  • CG11048-PA [Drosophila melanogaster]gi|16768214|gb|AAL28326.1| GH24459p [Drosophila melanogaster]gi|19922624|ref|NP_611459.1| CG11048-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(16127612..16127662,16127717..16128270,16128392..16128911,16128979..16129500,16129625..16130275); ID=FBpp0085625; name=CG11048-PA; parent=FBgn0034487,FBtr0086316; dbxref=FlyBase:FBpp0085625,FlyBase_Annotation_IDs:CG11048-PA,GB_pro [fly-100309-contam.fasta]
  • CG11048-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH24459p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(16127612..16127662,16127717..16128270,16128392..16128911,16128979..16129500,16129625..16130275); ID=FBpp0085625; name=CG11048-PA; parent=FBgn0034487,FBtr0086316; dbxref=FlyBase:FBpp0085625,FlyBase_Annotation_IDs:CG11048-PA,GB_protein:AAF57502.2,REFSEQ:NP_611459,GB_protein:AAF57502; MD5=fa5464838bcba5ed770a9c9563ae84f5; length=765; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(16127612..16127662,16127717..16128270,16128392..16128911,16128979..16129500,16129625..16130275); ID=FBpp0085625; name=CG11048-PA; parent=FBgn0034487,FBtr0086316; dbxref=FlyBase:FBpp0085625,FlyBase_Annotation_IDs:CG11048-PA,GB_protein:AAF57502.2,REFSEQ:NP_611459,GB_protein:AAF57502; MD5=fa5464838bcba5ed770a9c9563ae84f5; length=765; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG11048 OS=Drosophila melanogaster GN=CG11048 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(16127612..16127662,16127717..16128270,16128392..16128911,16128979..16129500,16129625..16130275); ID=FBpp0085625; name=Efhc1.2-PA; parent=FBgn0034487,FBtr0086316; dbxref=FlyBase:FBpp0085625,FlyBase_Annotation_IDs:CG11048-PA,GB_protein:AAF57502.2,REFSEQ:NP_611459,GB_protein:AAF57502,FlyMine:FBpp0085625,modMine:FBpp0085625; MD5=fa5464838bcba5ed770a9c9563ae84f5; length=765; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • CG11048 OS=Drosophila melanogaster GN=Efhc1.2 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2R:join(20240107..20240157,20240212..20240765,20240887..20241406,20241474..20241995,20242120..20242770); ID=FBpp0085625; name=Efhc1.2-PA; parent=FBgn0034487,FBtr0086316; dbxref=FlyBase:FBpp0085625,FlyBase_Annotation_IDs:CG11048-PA,GB_protein:AAF57502.2,REFSEQ:NP_611459,GB_protein:AAF57502,FlyMine:FBpp0085625,modMine:FBpp0085625; MD5=fa5464838bcba5ed770a9c9563ae84f5; length=765; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(20240107..20240157,20240212..20240765,20240887..20241406,20241474..20241995,20242120..20242770); ID=FBpp0085625; name=Efhc1.2-PA; parent=FBgn0034487,FBtr0086316; dbxref=FlyBase:FBpp0085625,FlyBase_Annotation_IDs:CG11048-PA,GB_protein:AAF57502.2,REFSEQ:NP_611459,GB_protein:AAF57502,FlyMine:FBpp0085625,modMine:FBpp0085625; MD5=fa5464838bcba5ed770a9c9563ae84f5; length=765; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • EFHC1 homologue 2 OS=Drosophila melanogaster GN=Efhc1.2 PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0085625 type=protein; loc=2R:join(20240107..20240157,20240212..20240765,20240887..20241406,20241474..20241995,20242120..20242770); ID=FBpp0085625; name=Efhc1.2-PA; parent=FBgn0034487,FBtr0086316; dbxref=FlyBase:FBpp0085625,FlyBase_Annotation_IDs:CG11048-PA,GB_protein:AAF57502.2,REFSEQ:NP_611459,GB_protein:AAF57502,FlyMine:FBpp0085625,modMine:FBpp0085625; MD5=fa5464838bcba5ed770a9c9563ae84f5; length=765; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(20240107..20240157,20240212..20240765,20240887..20241406,20241474..20241995,20242120..20242770); ID=FBpp0085625; name=Efhc1.2-PA; parent=FBgn0034487,FBtr0086316; dbxref=FlyBase:FBpp0085625,FlyBase_Annotation_IDs:CG11048-PA,GB_protein:AAF57502.2,REFSEQ:NP_611459,GB_protein:AAF57502,UniProt/TrEMBL:Q7K2N1,FlyMine:FBpp0085625,modMine:FBpp0085625; MD5=fa5464838bcba5ed770a9c9563ae84f5; length=765; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 765 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cilium assembly [UNKNOWN]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRLPGMPML PGAQFYDRGK RRHPRQQTLM HYQGIQMLSD RREPELVEPN GIVADPKCPP  60
   61 VPAQLNSLWA PKATTKLPPW LAYDKQVLCF NAYFKENLTE IYHAPYQVRK VKIFFYLEDG 120
  121 TMQVTEPKVE NSGIPQGCLV HRQRIPKAPP TDREFISIFD LNVDTDVQIF DRVYHISGCD 180
  181 VFTRQFLNRA GIFVPEAQQE PCDPTTEIRK RSGLKQTGNT ATSALPKKHA FAQFLEFDRR 240
  241 VLKFQGYWND RSEFGDVRKL EVCYYLADDT IDIKEKFPRN SGREGPTTFL KRGKLPKEFS 300
  301 GLPLPGQQTA MTLLNVLGNS MRDVRYVADP LNTGQKEVQH YTDQDLQIGA VLNVFGRSVV 360
  361 LTSCDQFTQS YYREKYGIQE FSPQPIPERS DIRPYTQGGM GSRRLPPYNG WGSHEDSEGN 420
  421 CITVEPKPPQ ADFKKLFKYD GCILRFGAKL ISAIRDNGER DFVISYFLAD DTLQIYETSR 480
  481 RNSGFLGGEF LKRARVPLPG QDMYSSSRPE YYRANDFYIG RTMTLKDHIF HIVSADEFTL 540
  541 MYMEQHPSEF PVADIQKIMQ KIREAVRPDY KQFVLRCKPD GDLGDYTAVS FETLRSTLLS 600
  601 YLSKDCLLNH EIVTVCRFFS AEQAMPPSCD RNRVRAAAQL ELKRALWNGM DQLNDHLSHI 660
  661 NPACKPYISE GQVRSTLRGC RLPFSLELVE DILMVLQRNG QNEIEVRDFL AFFNMRNDQV 720
  721 PDIAPLNIAF ELCPKLPFLH KGRLVDFTWF LDYLGIEEEL KRANN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] MSA 1.044988 View MSA. No confident structure predictions are available.
    2 View Details [97..250] MSA 4.050986 View MSA. No confident structure predictions are available.
    3 View Details [251..411] MSA 1.08496 View MSA. No confident structure predictions are available.
    4 View Details [412..765] PSI-BLAST 28.522879 Calpain large subunit, C-terminal domain (domain IV); Calpain large subunit, middle domain (domain III); Calpain large subunit, catalytic domain (domain II)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  2.59835122922082 bayes_pls_golite062009
  • protein binding
    		•  1.36984860219682 bayes_pls_golite062009
  • cation binding
    		•  1.15687545864836 bayes_pls_golite062009
  • metal ion binding
    		•  1.15687545864836 bayes_pls_golite062009
  • ion binding
    		•  1.14952446266244 bayes_pls_golite062009
  • calcium ion binding
    		•  0.94710748110495 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.27738240687034 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle