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Protein Overview: sec6-PA

General Information:
Name(s) found: sec6-PA / FBpp0085888 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene sec6 is referred to in FlyBase by the symbol Dmel\sec6 (CG5341, FBgn0034367). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14512772..14515249. It has the cytological map location 55E2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: instar larval development; photoreceptor cell maintenance; protein transport; rhabdomere membrane biogenesis; photoreceptor cell morphogenesis; rhabdomere development; plasma membrane organization; positive regulation of exocytosis. 15 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 738 amino acids

    Gene Ontology:
    Cellular Component: zonula adherens [IDA]
    exocyst [ISS][NAS]
    rhabdomere [IDA]
    Biological Process: synaptic vesicle targeting [ISS][NAS]
    synaptic vesicle docking during exocytosis [ISS][NAS]
    plasma membrane organization [IMP]
    vesicle-mediated transport [ISS]
    photoreceptor cell morphogenesis [IMP]
    rhabdomere development [IMP]
    photoreceptor cell maintenance [IMP]
    protein transport [IMP]
    rhabdomere membrane biogenesis [IMP]
    neurotransmitter secretion [NAS]
    instar larval development [IMP]
    positive regulation of exocytosis [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLQQLEEQA RQAALKDIQN MLQRPGQLEK VEQYRHRIAR KKASVEALLK TGMQGQLDGV  60
   61 RVGLKQLETC MQDVREVRRR MDEVERLLRG VPEVYDALEV VREENTKHSQ YATAMENLKH 120
  121 IFNVDASVQK TMALIEDDKL LNAHQCLADL ENSRDDLLYE LHKQPKQHAS DKITLKRHFE 180
  181 KVDTVSQELE KKLRLILSRT LNTLRKKPTI IVTALRIIER EEKNDQFALQ QQKVTGFLPP 240
  241 GRPKAWRRMI MDVLQQSVIT RIEGSKLEER ADNKMWLVRD LEILRQIILE DLRVVKSLCV 300
  301 PCFPPHYDIF GEYVKFYHEG LSSYLDNIVR SGLEGNEYVS MMAWVTHTYP GVELMSHPDL 360
  361 NVDVHRQIGT LLRPEHLKAL EDEYLQNMQR NFQEWMTKAA ETEKQEWFTE TVPDQDEEYY 420
  421 HTSAPVIIFQ MIDQHLQVTN TIHQELTFKA LVMSIQQVEI FGQTYLKNVI ELKEHHFRNR 480
  481 DQIKYFTHYI ITIVNNSQQM VELAQQMKQL YWPKSRTEHY EDFERLLATF QRIRAHAASY 540
  541 LLEEAFLDME CHFNDLFTAK WLASNIAVDT ICVTLDDYFQ DYNHLRPNNF EMVINEAQKL 600
  601 LAKRYIRALL SKRLSKPRAE CDAITRKIKT EAKRFKLFFE KIAPKISLSD SPLDLISTLS 660
  661 ALLSSDIELL VLDLHTLLGS YPSLNEDHLV RLFYIRNDVK AAEVREKVQD AMKSKKAMVS 720
  721 IAKQDCIFKE IVFSDKLW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..363] PSI-BLAST 13.154902 Heavy meromyosin subfragment
    2 View Details [364..738] PSI-BLAST 42.0 No description for 2fji1 was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle