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Protein Overview: Atg7-PA

General Information:
Name(s) found: Atg7-PA / FBpp0085891 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Autophagy-specific gene 7 is referred to in FlyBase by the symbol Dmel\Atg7 (CG5489, FBgn0034366). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14507961..14512553. It has the cytological map location 55E2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding; catalytic activity. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; macroautophagy; autophagy; larval midgut cell programmed cell death. 9 alleles are reported. The phenotype of these alleles is annotated with: adult brain. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 684 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: larval midgut cell programmed cell death [IMP]
    autophagy [IMP]
    determination of adult lifespan [IMP]
    macroautophagy [IMP]
    Molecular Function: catalytic activity [IEA]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTEKEIILQ FAPWESFVSP TFWHKLAELK LDHDRLSDSK RSITGHYTNR NASGCLLEVD  60
   61 YTAYNRMAKP PKFSHSAIGT IYNKNTIEEF KALDKLQLLA DEGKELLADM CSGGALRDPS 120
  121 LLTRFFVLSF ADLKCHSYYY WFAFPCPLTP TLKLQGAVQK LRDLPNSSSY IMALKALPTE 180
  181 SQNFFILYAN VEKNIFEARS LSSLDDKNVE FCYFGFADPS EYEHPAWIMR NYAAFLLQQC 240
  241 PSFVGKPLKF LGLRHNQQMN IDDSLVWKVI QTEACDLSQS ENIKFVGWEL NKNGKMGPRM 300
  301 VCMRDSMDPA KLAENSVNLN LKLMKWRLVP DLNLEIISQT KCLLFGAGTL GCAVARNLLS 360
  361 WGFKHITLLD SGKVGFSNPV RQNLYTHADA VAGNRMKATT AAQRLKEINP SAETAGYVLE 420
  421 IPMPGHTIGE SLLAQTKEHL KVIEKLVQDH DVIFLLTDSR ESRWLPTLLG AAKEKIVINA 480
  481 ALGFDSYLVM RHGTTRKEAG DDGQEIEGLK CINGDQLGCY FCNDVTAPGN SLKDRTLDQQ 540
  541 CTVTRPGVSN IAASYAVELL VALLQHPRKE LAPAYYAQSG RGRSEETEEK VPEGLLGILP 600
  601 HSIRGMLCNY ENILPATQKF AQCIACSAAV LNEYKKEGHA FLFKTFETAK FLEDLTGISE 660
  661 FKRLNSEIID FDDEEFDMSD SDED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] MSA 1.041969 View MSA. No confident structure predictions are available.
    2 View Details [149..312] MSA 3.401993 View MSA. No confident structure predictions are available.
    3 View Details [313..684] PSI-BLAST 50.154902 No description for 2nvuB was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle