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Protein Overview: Pepck-PA

General Information:
Name(s) found: Pepck-PA / FBpp0085880 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Phosphoenolpyruvate carboxykinase is referred to in FlyBase by the symbol Dmel\Pepck (CG17725, FBgn0003067). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14424272..14426924. It has the cytological map location 55D3. Based on sequence similarity, it is predicted to have molecular function</span>: phosphoenolpyruvate carboxykinase (GTP) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: gluconeogenesis. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 647 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISS]
    Biological Process: gluconeogenesis [ISS][NAS]
    Molecular Function: GTP binding [IEA]
    phosphoenolpyruvate carboxykinase (GTP) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPELIEQSKI ISGNVCGLPQ LHKLRQDNCG LYSHIRGIPI SYGNVDLLTT GVRAFVEEGI  60
   61 ALCQPDQVHI CDGSEQENKV LIKSLLEAGT IVPLPKYDNC WLARTNPADV ARVESRTFIC 120
  121 TERREETIPT PVEGVKGTLG NWISPSDMDA AVQQRFPGCM KGRTMYVVPF SMGPVGSPLS 180
  181 KIGIELTDSA YVVASMRIMT RMGAAVLRQL AKKEEFVRAL HSVGAPANGQ VEQPSWPCDP 240
  241 ERTIILHKPA ENLIVSYGSG YGGNSLLGKK CFALRIGSTI AKQEGWLAEH MLILGITDPK 300
  301 GEKKYITAAF PSACGKTNLA MLNPSLANYK VECVGDDIAW MKFDSQGVLR AINPENGFFG 360
  361 VAPGTSMETN PIAMNTVFKN TIFTNVASTS DGGVFWEGME SSLAPNVQIT DWLGKPWTKD 420
  421 SGKPAAHPNS RFCTPAAQCP IIDEAWEDPA GVPISAMLFG GRRPAGVPLI YEARDWTHGV 480
  481 FIGAAMRSEA TAAAEHKGKV IMHDPFAMRP FFGYNFGDYV AHWLSMEKRG QVPKIFHVNW 540
  541 FRKSAEGKFM WPGYGENSRV LEWILRRVNG ESCYVDSAIG HIPAEGALNL DGMKDKVDVK 600
  601 EIFSLPKEFW SQEVKDIRTY FESQVGADLP ASIYQQLDEL SSRVDNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..647] PSI-BLAST 1000.0 No description for 2qewA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle