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Protein Overview: grh-PL

General Information:
Name(s) found: grh-PL / FBpp0289766 [FlyBase]
Description(s) found:
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  • gi|28573537|ref|NP_476844.2| grainy head, isoform L [Drosophila melanogaster] [NCBI NR]
  • gi|28380742|gb|AAF57784.3| grainy head, isoform L [Drosophila melanogaster] [NCBI NR]
  • The gene grainy head is referred to in FlyBase by the symbol Dmel\grh (CG42311, FBgn0259211). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13690294..13729118. It has the cytological map location 54E10-54F1. There is experimental evidence that it has the molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; nervous system development; tracheal outgrowth, open tracheal system; regulation of cell proliferation; open tracheal system development; regulation of tube length, open tracheal system; plasma membrane organization; chitin-based embryonic cuticle biosynthetic process. 70 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; embryonic/larval tracheal system; cephalopharyngeal skeleton; portion of tissue; cuticle; adult segment; adult mesothoracic segment; adult neuroblast; embryonic dorsal branch; embryonic/larval visceral branch; embryonic dorsal trunk; wing hair; embryonic tracheal system; embryonic ganglionic branch; plasma membrane part. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
  • >CG5058-PC translation from_gene[CG5058 grh FBgn0004586] seq_release:3 mol_weight=140873 cds_boundaries:(2R:12,872,136..12,904,596[+]) aa_length:1302 transcript_info:[CG5058-RC seq_release:3] gene_info:[gene symbol:grh FLAGGED_PROBLEMATIC FBgn0004586 g [hmr_yeast5_DM3-1_pombe.fasta]
  • CG5058-PC, isoform C [Drosophila melanogaster]gi|28573537|ref|NP_476844.2| CG5058-PC [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(13695916..13697159,13708505..13708916,13714639..13714833,13714900..13715514,13715836..13716059,13716248..13716410,13718502..13718613,13719176..13719270,13722120..13722176,13723256..13723354,13726547..13726726,13726820..13726944,1 [fly-100309-contam.fasta]
  • CG5058-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • grainy head CG5058-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(13695916..13697159,13708505..13708916,13714639..13714833,13714900..13715514,13715836..13716059,13716248..13716410,13718502..13718613,13719176..13719270,13722120..13722176,13723256..13723354,13726547..13726726,13726820..13726944,13727099..13727294,13727940..13728004,13728253..13728379); ID=FBpp0289766; name=grh-PL; parent=FBgn0259211,FBtr0300539; dbxref=FlyBase:FBpp0289766,FlyBase_Annotation_IDs:CG42311-PL,REFSEQ:NP_476844,GB_protein:AAF57784; MD5=1a50dcaf280be87268f2b696237951d4; length=1302; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(13695916..13697159,13708505..13708916,13714639..13714833,13714900..13715514,13715836..13716059,13716248..13716410,13718502..13718613,13719176..13719270,13722120..13722176,13723256..13723354,13726547..13726726,13726820..13726944,13727099..13727294,13727940..13728004,13728253..13728379); ID=FBpp0289766; name=grh-PL; parent=FBgn0259211,FBtr0300539; dbxref=FlyBase:FBpp0289766,FlyBase_Annotation_IDs:CG42311-PL,REFSEQ:NP_476844,GB_protein:AAF57784; MD5=1a50dcaf280be87268f2b696237951d4; length=1302; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Isoform C of Protein grainyhead OS=Drosophila melanogaster GN=grh [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(13695916..13697159,13708505..13708916,13714639..13714833,13714900..13715514,13715836..13716059,13716248..13716410,13718502..13718613,13719176..13719270,13722120..13722176,13723256..13723354,13726547..13726726,13726820..13726944,13727099..13727294,13727940..13728004,13728253..13728379); ID=FBpp0289766; name=grh-PL; parent=FBgn0259211,FBtr0300539; dbxref=FlyBase:FBpp0289766,FlyBase_Annotation_IDs:CG42311-PL,REFSEQ:NP_476844,GB_protein:AAF57784,FlyMine:FBpp0289766,modMine:FBpp0289766; MD5=1a50dcaf280be87268f2b696237951d4; length=1302; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(17808411..17809654,17821000..17821411,17827134..17827328,17827395..17828009,17828331..17828554,17828743..17828905,17830997..17831108,17831671..17831765,17834615..17834671,17835751..17835849,17839042..17839221,17839315..17839439,17839594..17839789,17840435..17840499,17840748..17840874); ID=FBpp0289766; name=grh-PL; parent=FBgn0259211,FBtr0300539; dbxref=FlyBase:FBpp0289766,FlyBase_Annotation_IDs:CG42311-PL,REFSEQ:NP_476844,GB_protein:AAF57784,FlyMine:FBpp0289766,modMine:FBpp0289766; MD5=1a50dcaf280be87268f2b696237951d4; length=1302; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(17808411..17809654,17821000..17821411,17827134..17827328,17827395..17828009,17828331..17828554,17828743..17828905,17830997..17831108,17831671..17831765,17834615..17834671,17835751..17835849,17839042..17839221,17839315..17839439,17839594..17839789,17840435..17840499,17840748..17840874); ID=FBpp0289766; name=grh-PL; parent=FBgn0259211,FBtr0300539; dbxref=FlyBase:FBpp0289766,FlyBase_Annotation_IDs:CG42311-PL,REFSEQ:NP_476844,GB_protein:AAF57784,FlyMine:FBpp0289766,modMine:FBpp0289766; MD5=1a50dcaf280be87268f2b696237951d4; length=1302; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of P13002, Isoform C of Protein grainyhead OS=Drosophila melanogaster GN=grh [DROME.fasta.20160308]
  • FBpp0289766 type=protein; loc=2R:join(17808411..17809654,17821000..17821411,17827134..17827328,17827395..17828009,17828331..17828554,17828743..17828905,17830997..17831108,17831671..17831765,17834615..17834671,17835751..17835849,17839042..17839221,17839315..17839439,17839594..17839789,17840435..17840499,17840748..17840874); ID=FBpp0289766; name=grh-PL; parent=FBgn0259211,FBtr0300539; dbxref=FlyBase:FBpp0289766,FlyBase_Annotation_IDs:CG42311-PL,REFSEQ:NP_476844,GB_protein:AAF57784,FlyMine:FBpp0289766,modMine:FBpp0289766; MD5=1a50dcaf280be87268f2b696237951d4; length=1302; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(17808411..17809654,17821000..17821411,17827134..17827328,17827395..17828009,17828331..17828554,17828743..17828905,17830997..17831108,17831671..17831765,17834615..17834671,17835751..17835849,17839042..17839221,17839315..17839439,17839594..17839789,17840435..17840499,17840748..17840874); ID=FBpp0289766; name=grh-PL; parent=FBgn0259211,FBtr0300539; dbxref=FlyBase:FBpp0289766,FlyBase_Annotation_IDs:CG42311-PL,REFSEQ:NP_476844,GB_protein:AAF57784,FlyMine:FBpp0289766,modMine:FBpp0289766; MD5=1a50dcaf280be87268f2b696237951d4; length=1302; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1302 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSTATTSV ITSNELSLSG HAHGHGHAHQ LHQHTHSRLG VGVGVGILSD ASLSPIQQGS  60
   61 GGHSGGGNTN SSPLAPNGVP LLTTMHRSPD SPQPELATMT NVNVLDLHTD NSKLYDKEAV 120
  121 FIYETPKVVM PADGGGGNNS DEGHAIDARI AAQMGNQAQQ QQQQQQQTEH QPLAKIEFDE 180
  181 NQIIRVVGPN GEQQQIISRE IINGEHHILS RNEAGEHILT RIVSDPSKLM PNDNAVATAM 240
  241 YNQAQKMNND HGQAVYQTSP LPLDASVLHY SGGNDSNVIK TEADIYEDHK KHAAAAAAAA 300
  301 GGGSIIYTTS DPNGVNVKQL PHLTVPQKLD PDLYQADKHI DLIYNDGSKT VIYSTTDQKS 360
  361 LEIYSGGDIG SLVSDGQVVV QAGLPYATTT GAGGQPVYIV ADGALPAGVE EHLQSGKLNG 420
  421 QTTPIDVSGL SQNEIQGFLL GSHPSSSATV STTGVVSTTT ISHHQQQQQQ QQQQQQQQQQ 480
  481 QHQQQQQHPG DIVSAAGVGS TGSIVSSAAQ QQQQQQLISI KREPEDLRKD PKNGNIAGAA 540
  541 TANGPGSVIT QKILHVDAPT ASEADRPSTP SSSINSTENT ESDSQSVSGS ESGSPGARTT 600
  601 ATLEMYATTG GTQIYLQTSH PSTASGAGGG AGPAGAAGGG GVSMQAQSPS PGPYITANDY 660
  661 GMYTASRLPP GPPPTSTTTF IAEPSYYREY FAPDGQGGYV PASTRSLYGD VDVSVSQPGG 720
  721 VVTYEGRFAG SVPPPATTTV LTSVHHHQQQ QQQQQQHQQQ QQQQQHHQQQ QHHSQDGKSN 780
  781 GGATPLYAKA ITAAGLTVDL PSPDSGIGTD AITPRDQTNI QQSFDYTELC QPGTLIDANG 840
  841 SIPVSVNSIQ QRTAVHGSQN SPTTSLVDTS TNGSTRSRPW HDFGRQNDAD KIQIPKIFTN 900
  901 VGFRYHLESP ISSSQRREDD RITYINKGQF YGITLEYVHD AEKPIKNTTV KSVIMLMFRE 960
  961 EKSPEDEIKA WQFWHSRQHS VKQRILDADT KNSVGLVGCI EEVSHNAIAV YWNPLESSAK1020
 1021 INIAVQCLST DFSSQKGVKG LPLHVQIDTF EDPRDTAVFH RGYCQIKVFC DKGAERKTRD1080
 1081 EERRAAKRKM TATGRKKLDE LYHPVTDRSE FYGMQDFAKP PVLFSPAEDM EKSFYGHETD1140
 1141 SPDLKGASPF LLHGQKVATP TLKFHNHFPP DMQTDKKDHI LDQNMLTSTP LTDFGPPMKR1200
 1201 GRMTPPTSER VMLYVRQENE EVYTPLHVVP PTTIGLLNAI ENKYKISTTS INNIYRTNKK1260
 1261 GITAKIDDDM ISFYCNEDIF LLEVQQIEDD LYDVTLTELP NQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..215] deduced N/A No confident structure predictions are available.
    2 View Details [216..382] MSA 1.187994 View MSA. No confident structure predictions are available.
    3 View Details [383..534] deduced N/A No confident structure predictions are available.
    4 View Details [535..739] MSA 4.234986 View MSA. No confident structure predictions are available.
    5 View Details [740..872] deduced N/A No confident structure predictions are available.
    6 View Details [873..947] deduced N/A No confident structure predictions are available.
    7 View Details [948..1160] deduced N/A No confident structure predictions are available.
    8 View Details [1161..1302] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.53

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle