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Protein Overview: Adgf-E-PA

General Information:
Name(s) found: Adgf-E-PA / FBpp0086611 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Adenosine deaminase-related growth factor E is referred to in FlyBase by the symbol Dmel\Adgf-E (CG10143, FBgn0033952). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10544303..10546260. It has the cytological map location 51B7-51B8. Based on sequence similarity, it is predicted to have molecular function</span>: growth factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: purine ribonucleoside monophosphate biosynthetic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 539 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IEA]
    extracellular region [ISS]
    Biological Process: purine ribonucleoside monophosphate biosynthetic process [IEA]
    Molecular Function: growth factor activity [ISS][NAS]
    adenosine deaminase activity [NAS]
    deaminase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVLLSHRML LAGWARRATP TAAQWIHHNP EKMTLLEMLG TTNLRKSTPK DYRILREIFN  60
   61 SFERYSGVGN DIQLTLPERA ANELIMCEKK REYEKGIMDP SKFAPGHHIF QVLTKVKKSP 120
  121 LFQILRRMPK GAALKAHDTS MCSSRVVIEI TYRDNLWVCT TQNGCRVEEF RFAKDKPKDV 180
  181 SFENGEWQPM EKLRELRGEE NLRKYLQMRF SMYPLASFTT NAHAWRHMMG IFGLLDGLLQ 240
  241 YAPVWGDYYY NALKEFYADG VQYLEVRSVL PQLYSLDGSR MPKRETVQIY KDTLERFKKE 300
  301 HPGFIDSKLI YAPIRHVQPE LVGEYIKECT ELNKEFPSFV VGFDLVGQED VGHPLSNFAA 360
  361 ELLKLPDHIH FYFHAGQTNW YGSHVDQNLL DAIVLGTKRI GHGYTITKHP VLMRLAKYLN 420
  421 IALEVCPVSN QVLQLGSDYR SHPAATLIAE NVPMVIASGS PGFWRAAPLS HDFYMAFLGI 480
  481 APMNADLKFL KRTAKNSIKY SSLKDEAKAE AMEKWKKQWD KWVENIVRQR KKDSETEKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..539] PSI-BLAST 65.69897 X-Ray Structure of Adenosine 5'-Monophosphate Deaminase from Arabidopsis Thaliana in Complex with Coformycin 5'-Phosphate

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  0.613054295683625 bayes_pls_golite062009
  • binding
    		•  0.341831157654067 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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