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Protein Overview: phyl-PA

General Information:
Name(s) found: phyl-PA / FBpp0086645 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene phyllopod is referred to in FlyBase by the symbol Dmel\phyl (CG10108, FBgn0013725). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10314841..10319840. It has the cytological map location 51A2. There is experimental evidence that it has the molecular function</span>: protein binding; protein self-association; protein binding, bridging; molecular adaptor activity. There is experimental evidence that it is involved in the biological process</span>: Ras protein signal transduction; sensory organ boundary specification; sensory organ precursor cell fate determination; regulation of Wnt receptor signaling pathway; compound eye photoreceptor cell differentiation; regulation of Notch signaling pathway; proteasomal protein catabolic process; R1/R6 cell fate commitment; peripheral nervous system development; R7 cell fate commitment. 35 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; organ system; abdominal transverse muscle; embryonic/larval hypodermal muscle; compound cell cluster organ; abdominal oblique muscle; eo support cell; multidendritic neuron. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 400 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS]
    ubiquitin ligase complex [IDA]
    Biological Process: sensory organ boundary specification [IMP]
    compound eye photoreceptor cell differentiation [IMP]
    R1/R6 cell fate commitment [IEP][IMP]
    sensory organ precursor cell fate determination [IMP]
    regulation of Notch signaling pathway [IDA]
    R7 cell fate commitment [IEP][IMP]
    R7 cell development [TAS]
    peripheral nervous system development [IMP]
    Ras protein signal transduction [IGI]
    regulation of Wnt receptor signaling pathway [IDA]
    proteasomal protein catabolic process [IDA]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPI]
    protein binding, bridging [IPI]
    protein self-association [IPI]
    molecular adaptor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTNQQQQAN PSAAVAAPAA SSEYLKRTCL ICGCHTNQTI NIYEPRSGPN IVQLIQAKFK  60
   61 FQPLNEDKFL CFSCNNWLIN WHSLQAVNSN EAESQSQSPS HMGNSVLQQE RTKLRPVAMV 120
  121 RPTVRVQPQS QPQLQPQVPI NPTPAPIVYS KRRASRRSAS VSRMSRVLRQ CCVESLRRSP 180
  181 KKRNQQSVFV CLRPQGQKRS NAICKVECVA PRRKPVERLV KDVAATATPT PVLNTQSTPT 240
  241 YQRFPQPSVD GKVVAMFRRL GTTLSREEPA AYSAESNPAC SKLPQIMSPL KEAPRWTRDL 300
  301 DDDEILLEFD TAISEVLPTA RYQVTHEENK ENQQAQEMEL ELEEEEEVDG RAELEVVQEA 360
  361 EAPLEPQSHH KQGNSHQNSH QASIQLAGLR LPMGLSISLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145] Pfam 6.920819 No description for PF07776.6 was found. No confident structure predictions are available.
    2 View Details [146..400] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.63

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle