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Protein Overview: PR2-PB

General Information:
Name(s) found: PR2-PB / FBpp0086890 [FlyBase]
Description(s) found:
Found 12 descriptions.
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  • The gene Fak-like tyrosine kinase is referred to in FlyBase by the symbol Dmel\PR2 (CG3969, FBgn0013955). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9030337..9040161. It has the cytological map location 49F3-49F4. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1255 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKREEAPGG GSQVALDGSS ASACSSLAAK NGASSPSKVP NNKHIIPADS ISVNKQLGTG  60
   61 EFGIVQQGVW SNGNERIQVA IKCLCRERMQ SNPMEFLKEA AIMHSIEHEN IVRLYGVVLA 120
  121 TDSLMLVTEL AHLRSLLECL KDSGLRVSFL TIPTLCEFAL QICNGMRYLE QKRLIHRDLA 180
  181 ARNILVFSKD KVKISDFGLS RALGVGKDYY KTNFNVNLKL PIAWCAPECI NYLRFTNASD 240
  241 VWAFGVCLWE MFSYGFQPWA ALTGLQILEA IDAPNYQRLE QPDCCPSEYY TLMMKCWQDD 300
  301 AAKRPRFGEI YDQLPDMKPE QLKAVVNCTE PKKDHLLYRQ GDIISVLDRN TGTPFWKGVL 360
  361 STGKTGYFNP SNTVAFLEGL PSSTRDSFSR VSDHRISKRK LRTEMISKPQ NDFKHTGHVG 420
  421 IDGATFGDIA FLGSSQNYNH VPKQIVTPYK PSEDIEQTPL LLPPTPTSPD SLQTASGYFP 480
  481 EGANSGGAMG TSMNPTFIPS AEHTPKLIAT NGQSSFDFAS GSTNPFFPNR GDDELEFGLH 540
  541 NYGADGKSVH SETGWRPTSR SIVDDPHEYH EISDDEIAAD KLDFGPSLLD EINSMFGSIS 600
  601 AATGSHPKSP GFDHVNNKNE ITEMSAKLGQ KSGDTNGNKH GHGLLPTLSK KKSSGTVKPI 660
  661 SVKDEKILNH AIEIANEISA RSMIDLVSDQ TPVIHSPKRK FSFRFPHLSN NGSGDKSGGL 720
  721 GTSGSAHTPT HGNASPFPKK KNFTEELQSI PDIQSLIGKE GLEAYNSLIE RKALLDIGPS 780
  781 PAATLLRHLD TDEFDLQSLH QSQRPMTLPT RGATQRVRKA ELAAGLSRHN DENSNSLEAC 840
  841 ESPSYMTHGS YKFPEAQPTE QLPEPESPNP IPLPPREGKK QVKTSTKRHV RKYPLIIPAN 900
  901 GLQRTLSKLA DFGDEAAKSP EISTSSQPQP GRAIEVVAAV RPSGMRRPSR PSEREYENMP 960
  961 TVGKESAHTY QNLDKLTPAD AAGLTDTASL QFESIMEADT SKEGILQSPD VTDGFYNFSI1020
 1021 QKEHYNKGKD AEFEATQISG LYVNDDELRN LDIESSRRTA TPCSSCSALE SEHSQPDALP1080
 1081 STESVSEVSR FSSVDNELAG NALFKKVRAS VNMAMNRKSV AETSLTSNQP GGASAKPQTE1140
 1141 AEYFAATAAR LADSNSVSCE DLLEFSDKKP KGCERGVDSD EVRIMVKVLG KDSTPNRCLG1200
 1201 ALEFINWDVH KSIKLIKLQN LVSEANLSLE ASFEALQQHE WDLHTTAHKL NGLKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..381] PSI-BLAST 84.30103 No description for 2qoqA was found.
    2 View Details [382..478] deduced N/A No confident structure predictions are available.
    3 View Details [479..632] deduced N/A No confident structure predictions are available.
    4 View Details [633..740] deduced N/A No confident structure predictions are available.
    5 View Details [741..919] deduced N/A No confident structure predictions are available.
    6 View Details [920..1176] MSA 2.235992 View MSA. No confident structure predictions are available.
    7 View Details [1177..1255] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle