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Protein Overview: FBpp0308762, Dgk...

General Information:
Name(s) found: FBpp0308762 [FlyBase]
Dgkepsilon-PA / FBpp0086966 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=2R:join(8645250..8645408,8645467..8646474,8646531..8646848,8646904..8647023); ID=FBpp0308762; name=Dgkepsilon-PB; parent=FBgn0020930,FBtr0339705; dbxref=FlyBase:FBpp0308762,FlyBase_Annotation_IDs:CG8657-PB; MD5=c50c8edf5cb652806c89f184ebcd44d5; length=534; release=r5.56; species=Dmel; [FlyBase]
  • The gene Diacyl glycerol kinase Ã?&#142;Ã?µ is referred to in FlyBase by the symbol Dmel\DgkÃ?&#142;Ã?µ (CG8657, FBgn0020930). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8645051..8647226. It has the cytological map location 49C2. There is experimental evidence that it has the molecular function</span>: diacylglycerol kinase activity. There is experimental evidence that it is involved in the biological process</span>: phosphorylation. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 534 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: intracellular signaling pathway [IEA]
    phosphorylation [IDA][NAS]
    activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [IEA]
    Molecular Function: diacylglycerol binding [ISS]
    diacylglycerol kinase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIGTIELSV EALIGSLLAL SILFAFCRSL LSEDFVSTFK TRHSWKSIKV LEQACFCNVC  60
   61 EILLTPSAGL FCDCCGLCTH ATPPCQRRAD REYRCKDKWL RNESSVRHLW VHGNLPMGVH 120
  121 CADCNEEVDH HVSTDPGLYG WRCAWCQRCY HNDCYTRADS MEACDLGEFK DMIFPPYSFV 180
  181 AARTRDSMRL HLASITPPDI ENWEPLIVIA NTKSGSSTGA NVLSLLRGYL HPLQVMELGS 240
  241 RGPQDALQWA AKASPRPCRI LVAGGDGTIG WVLNTIYTLN IKPQPSVAIM PLGTGNDLSR 300
  301 VLGWGAEPPS VLDPVKILRS IRRARSVNLD RFDLQIEKLH YRLPIQRHPT KTIHVYNYFS 360
  361 VGVDAYITYN FHKTRESRFY LLSSRIFNKL LYFTFGTQQV MQPGCEHIEE KLTLYLDNKP 420
  421 VQLPELQALV FLNIDSWGAG CKLCELSNAN GEVRIVNSIS DGMMEVFGIV SSFHIAQLQC 480
  481 NISKPVRIGQ AKQIRLQVKE TVPMQADGEP WMQSPADIRL SSRSQARVLK LAAT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] PSI-BLAST 28.69897 No description for 2i13A was found.
    2 View Details [89..263] PSI-BLAST 3.522879 No description for 2dtgE was found.
    3 View Details [264..534] PSI-BLAST 30.0 No description for 2jgrA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • growth factor binding
    		•  1.70644792275756 bayes_pls_golite062009
  • binding
    		•  1.5999230777495 bayes_pls_golite062009
  • protein binding
    		•  1.3386243032188 bayes_pls_golite062009
  • insulin-like growth factor binding
    		•  1.19980610654863 bayes_pls_golite062009
  • catalytic activity
    		•  0.642251326160819 bayes_pls_golite062009
  • kinase activity
    		•  0.274732976887007 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.245530535394088 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.240453939259414 bayes_pls_golite062009
  • protein kinase activity
    		•  0.211411765325798 bayes_pls_golite062009
  • transferase activity
    		•  0.198357936114826 bayes_pls_golite062009
  • insulin-like growth factor I binding
    		•  0.0590759454300001 bayes_pls_golite062009
    3
    Term Confidence Notes
  • kinase activity
    		•  1.93010589087203 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.6993468998669 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.62136531467279 bayes_pls_golite062009
  • transferase activity
    		•  1.1287574677626 bayes_pls_golite062009
  • catalytic activity
    		•  0.704900964793432 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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