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Protein Overview: CG8860-PA

General Information:
Name(s) found: CG8860-PA / FBpp0087119 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8860 (CG8860, FBgn0033691). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8066988..8067392. It has the cytological map location 48E6. Based on sequence similarity, it is predicted to have molecular function</span>: protein transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: SRP-dependent cotranslational protein targeting to membrane, translocation; protein transport. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 68 amino acids

    Gene Ontology:
    Cellular Component: integral to endoplasmic reticulum membrane [ISS]
    Sec61 translocon complex [ISS]
    Biological Process: SRP-dependent cotranslational protein targeting to membrane, translocation [ISS]
    protein transport [ISS]
    Molecular Function: P-P-bond-hydrolysis-driven protein transmembrane transporter activity [IEA]
    protein transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKVVKFAEP GRAFAKDSIR LVKRCTKPDR KEFQKIAIAT AVGFAIMGFI GFFVKLIHIP  60
   61 INNIIVGS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] PSI-BLAST 3.522879 The structure of a protein conducting channel


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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