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Protein Overview: FBpp0308560, CG1...

General Information:
Name(s) found: FBpp0308560 [FlyBase]
CG12344-PA / FBpp0087341 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=2R:complement(6716161..6716361,6716460..6716564,6716643..6716771,6716887..6717251,6717310..6717465,6718883..6719037,6719119..6719218,6720630..6720706,6721313..6721374); ID=FBpp0308560; name=CG12344-PC; parent=FBgn0033558,FBtr0339477; dbxref=FlyBase:FBpp0308560,FlyBase_Annotation_IDs:CG12344-PC; MD5=ae48af31f1eb0c38e09ee0a86e211d34; length=449; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG12344 (CG12344, FBgn0033558). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6714934..6721741. It has the cytological map location 47C1-47C2. Based on sequence similarity, it is predicted to have molecular function</span>: extracellular-glycine-gated chloride channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ion transport. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 449 amino acids

    Gene Ontology:
    Cellular Component: glycine-gated chloride channel complex [ISS]
    postsynaptic membrane [IEA]
    Biological Process: ion transport [IEA]
    Molecular Function: extracellular-glycine-gated chloride channel activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDKFNTNAF ISFGLGFILM WLSEATEAHM NYTAKPRVVL PPNYVKEIRP PSKKGSPVIV  60
   61 DFSIFVVDIN SINVEDMDFR VDMFIHQRWL ESRLEIPDDI FEEGDDYVTL LPEVFENFWQ 120
  121 PDPYFLNSKI AEIATLTHKF TSVTLYKNKT VRYAARMHAI IACQMEFQLY PMDIQVCPIY 180
  181 IESFSSNNQK VKLRWSDSGV TLNPELKLLQ YNLGQPLELE ESDGYMPEKV GNFSRLTVYF 240
  241 RFERQIGHHL IQTFAPSSLV VMLSWFSFWL GLDAIPGRVT LLVTCMLTLV TMFTGADIPP 300
  301 VAYVKALDLW MAGCMLSVFA ALAEFVVVKV LDVQYQYQVN RIPKVLPMRI SNMEKGQCAT 360
  361 VASWEGGAVR SRKATQTPTT PGQTSLQGNG GPPKPARRQS LLSVAWTDTD TGVEKIMWRE 420
  421 IDKVSRAVFP ILFFVFVLLY WPILLMKSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..449] PSI-BLAST 56.39794 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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