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Protein Overview: CAP-PF

General Information:
Name(s) found: CAP-PF / FBpp0087431 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6156528..6194529. It has the cytological map location 46F9-47A1. Based on sequence similarity, it is predicted to have molecular function</span>: vinculin binding. The biological processes in which it is involved are not known. 23 alleles are reported. No phenotypic data is available. It has 17 annotated transcripts and 17 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 811 amino acids

    Gene Ontology:
    Cellular Component: focal adhesion [ISS]
    Biological Process: NONE FOUND
    Molecular Function: vinculin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFAPKFKARA PPGSGVWTPY GSSGDLNQSG ATSATPPPPP PPSLPVWTPQ PSPVLSGRKE  60
   61 FRPVRFESPT LPRRYTAQQQ QKTTTTIPPW SSAENGEGGP PPTAPASLNS VNSNSDYAET 120
  121 DCSGHFGPVA PSASVSDKIR TFERSSSNSE LQRPFVRRQL SDASRPAYRP NEVIYKVKHE 180
  181 YMSEPETGSD RPRKMAQLGR RQYDGIGPVT NDGMPIILRS EVKEPHQHEW YKRLYQTIHK 240
  241 QKNGDDFVIR YKCPRARPSY KSNGYVSEPE PNYDSDYSTV RYRTQNPHRV QSVSSAVNVR 300
  301 NLNQDEKLYG TMPNPIKSAQ NSYKNQPGRI ENYTTGHSSV SEKEKKEWWD EVMDIFNGNL 360
  361 EQSKLSPLYT EGNLSRALAK ESGYTSDSNL VFRKKEVPVS SPLSPVEQKQ AYKSLQAGGE 420
  421 PPLLGFRKPA PEKPRDLDPN APPIPPQPPV KGLSSYDFPY STDTVDGSDV NIHFKTPIRH 480
  481 EQRQNLSEEE LAIRQAEHMQ KLYHEERRRK YLQELQDMNS RRHTDNFTPS QKSPIALNRY 540
  541 DDFPTDVTLK SLVGPKTVAR ALFNFQGQTS KELSFRKGDT IYIRRQIDAN WYEGEHNAMI 600
  601 GLLPASYVEI VSRDGARTPS KRPSEGQARA KYNFQAQSGI ELSLNKGELV TLTRRVDGNW 660
  661 FEGKIANRKG IFPCSYVEVL TDIGAEDIAA RTTTVITSQS TTNLRPNLDV LRTNINNEFN 720
  721 TLTQNGAQPP NGILKETRTL HKTDALHVDT SSEPLAYRAL YKYRPQNSDE LELLEGDVVH 780
  781 VLEKCDDGWF VGTSQRTGCF GTFPGNYVER A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..217] MSA 2.227993 View MSA. No confident structure predictions are available.
    2 View Details [218..341] MSA 4.241989 View MSA. No confident structure predictions are available.
    3 View Details [342..555] deduced N/A No confident structure predictions are available.
    4 View Details [556..811] PSI-BLAST 36.522879 Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.13376047180398 bayes_pls_golite062009
  • protein binding
    		•  1.03382488697656 bayes_pls_golite062009
  • signal transducer activity
    		•  0.69727426993974 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.69727426993974 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle