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Protein Overview: Def-PA

General Information:
Name(s) found: Def-PA / FBpp0087518 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • The gene Defensin is referred to in FlyBase by the symbol Dmel\Def (CG1385, FBgn0010385). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5941683..5942081. It has the cytological map location 46D9. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: defense response to Gram-positive bacterium; antibacterial humoral response. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 92 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    Biological Process: positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [NAS]
    antibacterial humoral response [IEP][ISS]
    defense response to bacterium [NAS][TAS]
    defense response to Gram-positive bacterium [IDA][TAS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFFVLVAIA FALLACVAQA QPVSDVDPIP EDHVLVHEDA HQEVLQHSRQ KRATCDLLSK  60
   61 WNWNHTACAG HCIAKGFKGG YCNDKAVCVC RN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..92] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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